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Clinical Oral Investigations

Ausgabe 1/2026

Inhalt (64 Artikel)

Transdentinal effects of flavonoid-based primers applied to caries-affected dentin on pulp cells

  • Open Access
  • Research

Beatriz Ometto Sahadi, Igor Paulino Mendes Soares, Chloe Gifford, Caroline Anselmi, Josimeri Hebling, Marcelo Giannini, Marco C. Bottino

Effect of ozone therapy on post-operative pain following mandibular third molar surgical extraction: a split-mouth randomized clinical trial

  • Open Access
  • Research

Luca Guaschino, Alessandro Vanzanelli, Piermarco Babando, Andrea Ricotti, Guglielmo Amedeo Ramieri, Andrea Roccuzzo, Paolo Appendino

Periosteal-secured suture and fixation device in horizontal guided bone regeneration: a retrospective study

  • Research

Kaio Henrique Soares, Daniel Palkovics, Jairo Evangelista Nascimento, Júlia Gomes Lucio de Araujo, Christopher Dunlevy, Poliana Mendes Duarte

Integrating genotype–phenotype correlations into the diagnostic workflow of odontogenic tumors and cysts: insights from a 69 lesion cohort

  • Open Access
  • Research

Sibel Elif Gültekin, Burcu Toközlü, Carina Heydt, Reinhard Büttner

Digital quantitative analysis of noncarious cervical Lesions, occlusal tooth Wear, and gingival recession: results from a 25-Year clinical Follow-Up study

  • Research

Caroline Vieira Maluf, Ronaldo Hirata, Eduardo Jose Veras Lourenço¹, Luis Fernando Pegoraro, Ricardo Guimarães Fischer, Daniel de Moraes Telles

Three-dimensional assessment of tooth movements in clear aligner treatment of moderate and severe crowding

  • Research

Margaret Eason, Sandra Khong Tai, Charlene Tai Loh, Aron Aliaga del Castillo, Rodrigo Teixeira, Nathan Hutin, Gaëlle Leroux, Marcela Lima Gurgel, Claudia Trindade Mattos, Antonio Carlos de Oliveira Ruellas, Mary Barkley, Eric Hannapel, Lucia Cevidanes

Oral cancer in women: clinical profile, risk factors, treatment outcomes and survival predictors in 32 years of experience

  • Research

Diovana de Melo Cardoso, Regiane Mazzarioli Pereira Nogueira, Gabrielle Dias Duarte, Anne Cristina de Faria Cocato, Daniene Tesoni Cassavara Ribeiro, Patricia Gonçalves Barbosa, Sebastião Conrado-Neto, Francisco Urbano Collado, Everton Pontes Martins, Aline Satie Takamiya, Vitor Bonetti Valente, Glauco Issamu Miyahara, Eder Ricardo Biasoli, Daniel Galera Bernabé

Bilateral in vivo assessment of mandibular chewing dynamics using multi-slice real-time MRI: the rotation-translation-ratio in normal and displaced TMJ discs

  • Research

E. Paddenberg-Schubert, D. Kubein-Meesenburg, S. Sedaghat, R. Bürgers, D. Voit, P. Proff, J. Frahm, S. Krohn

Salivary metabolite-based prediction of radiotherapy-induced oral mucositis and candidiasis

  • Research

Saga Ramsay, Eelis Hyvärinen, Jopi Mikkonen, Wilfredo Alejandro González-Arriagada, Tuula Salo, Márcio Ajudarte Lopes, Bina Kashyap, Arja M. Kullaa

Leveraging three-dimensional craniofacial morphology for customized abutment design using facial scanning technology

  • Research

Kaijin Lin, Yongqing Guo, Shuang Wu, Wencan Ning, Jin Yang, Dong Wu, Jianbin Guo

Prospective functional assessment after mandible reconstruction and bone healing assessment

  • Open Access
  • Research

Philipp Ruf, Katharina Duda, Jakob Fenske, Vincenzo Orassi, Philipp Lampert, Henri Kreiker, Sara Checa, Max Heiland, Carsten Rendenbach, Claudius Steffen

Quality, usefulness, reliability, and accuracy of YouTube™ information on dental visits for children with autism: a cross-sectional study

  • Research

Nuria Pérez-Guzmán, María Pilar Pecci-Lloret, Francisco Javier Rodríguez-Lozano

Speech outcome following primary furlow palatoplasty with buccal myomucosal flap versus two flap palatoplasty in patients with cleft palate

  • Open Access
  • Research

Shaimaa Mohsen Refahee, Mamdouh Ahmed Aboulhassan, Iman Mohamed Elrouby, Mohamed Abd-El-Ghafour

The systemic impact of periodontitis in about 100,000 patients: associations with heart diseases, cancer, and mortality

  • Open Access
  • Research

Friederike Weinbecker, Susanne Nahles, Robert Preissner, Max Heiland, Florian Kernen, Saskia Preissner

Effects of cleaning protocols on surface roughness and optical properties of thermoplastic orthodontic retainers

  • Open Access
  • Research

Xiaoxian Huang, Ao Jia, Mengxia Peng, Jian Liang, Ziyi Wei, Hongshan Ge, Zhihua Li

A new method for continuous in vivo pH measurement in saliva and oral biofilm - a comparative pilot study

  • Open Access
  • Research

Antje Geiken, Ariel Salomon Gutman, Niklas Röder, Louise Holtmann, Christian Graetz, Karin Schwarz, Christof E. Dörfer

Synthesis, characterization and evaluation of novel bleaching gels containing bioactive glass and nano-hydroxyapatite on hydrogen peroxide diffusion, bleaching efficacy and enamel protection

  • Research

Adrieli Burey, Byron Carpio-Salvatierra, Michael Favoretto, María Luján Méndez Bauer, Viviane Hass, Alessandra Reis, Alessandro D. Loguercio, Paulo Vitor Farago

Intraseptal injection as an alternative for palatal infiltration in vital maxillary first permanent molars of 6- to 18-year-old patients: a non-inferiority randomised controlled trial

  • Research

Pimpisuth Nithikhun, Papimon Chompu‑inwai, Chanika Manmontri, Nattakan Chaipattanawan, Peecharat Areenoo, Areerat Nirunsittirat, Phichayut Phinyo

Bioactive inorganic materials in dental resin infiltrants: a systematic and critical review of their effects on infiltrant properties and tooth surfaces

  • Review

Abdullah Essa Aldarisi, Nourah Barrak Alsudairi, Leen Saleh Almutairi, Raand Abdulmohsen Altayyar, Shakil Ahmad, Danish Muzaffar, Abdul Samad Khan

Effect of print orientation of 3D-printed aligner templates on the volumetric accuracy of transferred composite attachments: an in vitro study

  • Research

Samuele Avolese, Simone Parrini, Danila Lava, Andrea Tancredi Lugas, Cristina Bignardi, Mara Terzini, Danila Muraca, Nicola Scotti, Fabrizio Sanna

Preventing enzymatic degradation of demineralized dentin collagen using a natural crosslinker

  • Open Access
  • Research

Anton Schestakow, Iris Xiaoxue Yin, Chun Hung Chu

Assessment of facial asymmetry in patients with orofacial cleft based on the biometric proposal of the average male face

  • Research

Gabriela Verbova, Kvetuse Lovasova, David Kachlik, Boris Verba, Peter Kizek, Miriama Slebodova, Ingrid Hodorova

Performance of low-viscosity resin composites containing S-PRG fillers under erosive challenge

  • Research

Daniella Cristo Santin, Juliana Carvalho Jacomine, Leonardo Masiero Fogaça, Marina Ciccone Giacomini, Heitor Marques Honório, Linda Wang

Letter to the editor

  • Debate

Raquel Osorio

Detection of Methicillin-resistant Staphylococcus aureus (MRSA) and biofilm formation among dental patients and dental health care workers: cross sectional study

  • Open Access
  • Research

Manal M. Darwish, Nashwa Naguib Omar, Rania Farouk, Kawther Ibrahim, Rasha Attia, Lamiaa M. EL-Moussely

Viral infections are associated with apical periodontitis: A meta-analysis of prevalence, clinical symptoms, and lesion sizes across 31 clinical studies

  • Review

Xinyue Liu, Yin Zou, Chuyi Jin, Yan Wang, Jiatong Zhang, Mengqing Yan, Yifan Xie, Mengyao Ding, Kun Wang, Lipei Liu, Cheng Ding, Xing Chen

Mapping dental biofilms: from plaque index through planimetry to volumetric analysis

  • Open Access
  • Research

Katja Povšič, Luka Fijavž, Haris Munjaković, Adrian Kašaj, Rok Gašperšič

Mapping the physiological, psychological and social landscape of the oral frailty network: a cross-sectional network analysis

  • Research

Sichen Xia, Ying Tao, Guangrui Cao, Yuanrong Wang, Qiantong Hang, Yichen Jiang, Wenbo Sun, Hua Wang, Xian Chen

Correlation of malocclusion and mouth breathing rates from a novel monitor

  • Open Access
  • Research

D. N. Li, Y. Z. Tu, Z. Lu, L. Mei, F. Hua, M. H. Li, R. B. Zhu, H. He, Y. Luo, K. Qi

Association of anterior crossbite and open bite with the number of remaining teeth: A cross-sectional study from the Tohoku medical megabank cohort

  • Open Access
  • Research

Kento Numazaki, Toru Tamahara, Takamasa Komiyama, Takako Numazaki, Maki Goto, Ritsuko Shimizu, Itaru Mizoguchi, Kaoru Igarashi, Hiroyasu Kanetaka

Postoperative pain and quality of life after the use of different endodontic sealers in asymptomatic molars: a randomized clinical trial

  • Open Access
  • Research

Patrícia Santos Oliveira, Meire Coelho Ferreira, Natália Gomes de Paula, Wallace Vieira Mendes, Thieny Gouveia dos Santos, Giulio Gavini, Leonardo Hunaldo dos Santos, Suellen Linares Lima, Renata Grazziotin-Soares, Ceci Nunes Carvalho

Orthonasal bioactive volatiles and their effects on salivation: a pilot study

  • Open Access
  • Brief Report

Wiktoria Potocka, Zainab Assy, Marja L. Laine, Floris J. Bikker

A novel classification of periodontal phenotype integrating hard and soft tissue parameters using data-driven clustering

  • Research

Abeer A. Al-Sosowa, Ehab A. Abdulghani, Anna Dai, Jia-ping Huang, Wang Meng, Jiajun Zhu, Pei-Hui Ding

Impact of postoperative radiotherapy and chemoradiotherapy on survival outcomes in oral squamous cell carcinoma patients with pN1 neck disease

  • Open Access
  • Research

Ann-Kristin Struckmeier, Ralf Smeets, Cordula Petersen, Christian Betz, Waldemar Wilczak, Martin Gosau

Skeletodental and soft tissue changes following treatment with herbst and pendex appliances: a retrospective CBCT study

  • Open Access
  • Research

Brianna Tucker, Jessica Kang, Christopher Hudson-Boyd, Sam Kadan, Bruno Saconi, Brendan T. Keenan, Richard J. Schwab, Chun-Hsi Chung, Hyeran Helen Jeon

The relationship between clinical severity of obstructive sleep apnea based on polysomnography and drug-induced sleep endoscopy with 3D, 2D, linear, and angular anatomical parameters of upper airway and craniofacial area in CBCTs of individuals with moderate or severe apnea: a cross-sectional study

  • Research

Farhad Sobouti, Gholamreza Bayazian, Sunjay Suri, Benjamin Pliska, Sepideh Dadgar, Mitra Ghazizadeh Ahsaie, Atabak Nikbakht, Reza Alizadeh-Navaei, Arash Khojasteh, Mehdi Aryana, Vahid Rakhshan

Load-bearing capacity of knife-edged monolithic zirconia crowns: effect of thickness and fabrication method

  • Research

Zhouchuan Cao, Qianqian Ye, Zhi Chen, Zhe Sun, Keying Shi, Jing Zhao, Yuanna Zheng

Immediate versus conventional loading in users of mandibular overdentures retained by narrow-diameter implants: results from a 5-year randomized clinical trial

  • Research

Salma Rose Buchnveitz Salybi, Fernanda Isabel Román Ramos, Anna Paula da Rosa Possebon, Otacílio Luiz Chagas-Júnior, Luciana de Rezende Pinto, Fernanda Faot

Lymph node metastasis pattern in recurrent and ipsilateral second primary oral squamous cell carcinoma

  • Research

Yijing Cai, Maged Ali Al-Aroomi, Jie Chen, Saiwen Song, Jie Wang, Canhua Jiang

Effect of cigarette smoke on surface roughness and bacterial adhesion of orthodontic aligners: an in vitro investigation

  • Open Access
  • Research

Kelly Galisteu-Luiz, Flávio de Mendonça Copello, Karla Lorene de França Leite, Mylena da Rocha Cavalcante, Larine Ferreira Lira, Kenderson Santos Silva, Sarah Pereira Martins, Ingrid Cristina Pinto da Costa, Gabriela Drago Vidal, Carlos Nelson Elias, Luísa Schubach da Costa Barreto, Margareth Maria Gomes de Souza

Osseous free flap vs. Bridging plate mandibular reconstruction: a retrospective cohort study on perioperative complications of 335 patients

  • Open Access
  • Research

Philipp Lampert, Jakob Fenske, Kilian Kreutzer, Henri Kreiker, Norbert Neckel, Steffen Koerdt, Max Heiland, Carsten Rendenbach

3D analysis of smile transformation in patients with class III deformities following orthognathic surgery: a stereophotogrammetric study

  • Open Access
  • Research

Alaz Enez, Nur Altıparmak, Berat Serdar Akdeniz, Sıdıka Sinem Akdeniz

Assessment of mid-term success in various types of zirconia implants: a retrospective clinical analysis

  • Open Access
  • Research

Belir Atalay, Yusuf Emes, Halim Işsever, Alanur Şahabettinoğlu, Buket Aybar, Tan Fırat Eyüboğlu, Mutlu Özcan

Fully automatic AI diagnosis of alveolar bone defect in anterior teeth on CBCT images

  • Research

Runzhi Guo, Ning Ma, Tianlei Shi, Yufeng Wang, Qianyi Qin, Zining Chen, Feifei Zuo, Yajie Wang, Weiran Li

Impact of AI-assisted decision support on radiological diagnosis of jawbone lesions

  • Research

Jonas Ver Berne, Soroush Baseri Saadi, Maria Fernanda Silva da Andrade-Bortoletto, Rocharles Fontenele, Reinhilde Jacobs

Neu im Fachgebiet Zahnmedizin

Ist die Mundmikrobiota mit Pankreaskrebs assoziiert?

In einer Kohortenstudie wurde ein Zusammenhang zwischen oralen Bakterien und Pilzen und dem Auftreten von Pankreaskarzinomen gesehen. Diese Assoziation könnte helfen, Patientinnen und Patienten für gezielte Vorsorgeuntersuchungen ausfindig zu machen.

Elektroschrott: Wie Praxen Altgeräte sicher entsorgen

Ob nun Sonogerät, Praxiscomputer oder gar TI-Konnektor: Einfach zum nächsten Wertstoffhof sollten Praxisteams ausgediente Elektrogeräte nicht bringen. Was bei der Entsorgung zu beachten ist. Und wie die Teams sicher sensible Daten auf PC-Festplatte, externem Datenspeicher und TI-Komponenten löschen.

Tipps: So können Praxen die Risiken für einen GOÄ-Streit minimieren

Für Streitigkeiten, die das GOÄ-Honorar betreffen, sind neuerdings nur noch Landgerichte zuständig. Das macht Prozesse teurer. Eine Praxisberaterin erläutert, wie Praxen vorbauen können, um solche Streitfälle und Gerichtsverfahren zu vermeiden.

Was wächst diesmal im Unterkiefer?

Eine 31-jährige, ansonsten gesunde Frau stellte sich in der Kopf- und Halschirurgie mit einer progredient zunehmenden Raumforderung im linken Unterkieferbereich vor. In der Vorgeschichte war ein pleomorphes Adenom reseziert worden. Worum könnte es sich dieses Mal handeln?

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Eine Speichelprobe wird entnommen/© Animaflora PicsStock / stock.adobe.com (Symbolbild mit Fotomodell), Ultraschalluntersuchung der Niere/© Your_Photo_Today (Symbolbild mit Fotomodellen), Richter mit Gesetzbuch/© Kzenon / stock.adobe.com (Symbolbild mit Fotomodell), Tonsillektomie Operation/© ShvedKristina - stock.adobe.com (Symbolbild mit Fotomodellen)