Ausgabe 10/2025
Inhalt (10 Artikel)
Double Peaking Phenomena in Pharmacokinetic Disposition Revisited
- Review Article
Malaz Yousef, Dion R. Brocks, Raimar Löbenberg, Neal M. Davies
Clinical Pharmacology Profile of the Claudin 18.2 Antibody Zolbetuximab
- Open Access
- Review Article
Jianning Yang, Akihiro Yamada, Kohei Shitara, Rui-Hua Xu, David Ilson, Sara Lonardi, Samuel J. Klempner, Yoko Ueno, Masato Takeuchi, Janet Pavese, Tomasz Wojtkowski, Maria Matsangou, Srinivasu Poondru
Challenging Traditional ADME Assumptions for Physiologically Based Pharmacokinetic Models for Intravenous Administration of Iron–Carbohydrate Nanomedicines: Potential Utility of Gold Nanoparticle Models as a Roadmap
- Open Access
- Review Article
Amy Barton Alston, Zhoumeng Lin, Heather Herd Gustafson, Beat Flühmann, Reinaldo Digigow, Vanesa Ayala-Nunez, Stephan Schmidt
Pharmacokinetics, Pharmacodynamics, and Urinary Recovery of Oral Mescaline Hydrochloride in Healthy Participants
- Open Access
- Original Research Article
Lorenz Mueller, Aaron Klaiber, Laura Ley, Anna M. Becker, Jan Thomann, Dino Luethi, Yasmin Schmid, Matthias E. Liechti
TDM-Based Tailored Dosing of Durvalumab in Lung Cancer Patients: A Comprehensive Population Pharmacokinetic–Pharmacoeconomic Evaluation
- Open Access
- Original Research Article
Fenna de Vries, Eric J. F. Franssen, Arthur A. J. Smit, Dirk Jan A. R. Moes, Anthonie J. van der Wekken, Thijs Oude Munnink, Jeroen J. M. A. Hendrikx, Daphne W. Dumoulin, Stijn L. W. Koolen, Wietske Kievit, Michel M. van den Heuvel, Rob ter Heine
The Influence of Patient Factors on the Population Pharmacokinetics of Colchicine: Implications for Safe and Effective Dosing
- Open Access
- Original Research Article
Daniel F. B. Wright, Hailemichael Z. Hishe, Nicola Dalbeth, Anne Horne, Jill Drake, Janine Haslett, Lisa K. Stamp
Population Modeling of Factor IX Activity Following Administration of Fidanacogene Elaparvovec Gene Therapy in Participants with Hemophilia B
- Open Access
- Original Research Article
Jessica Wojciechowski, Puneet Gaitonde, Jim H. Hughes, Patanjali Ravva
Role of Antidrug Antibodies in Oncolytic Viral Therapy: A Dynamic Modelling Approach in Cancer Patients Treated with V937 Alone or in Combination
- Open Access
- Original Research Article
Zinnia P. Parra-Guillen, Iñaki F. Trocóniz, Tomoko Freshwater
A Phase IIa, Single-Blind, Placebo-Controlled, Parallel-Group Study to Assess Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of Brensocatib in Adults with Cystic Fibrosis
- Open Access
- Original Research Article
Michael W. Konstan, James J. Tolle, Emily DiMango, Patrick A. Flume, Helen Usansky, Ariel Teper, Christina N. Ramirez, Jimmy Flarakos, Jessica Basso, Sherry Li, Marcela Vergara
Drug–Drug Interactions Between Direct Oral Anticoagulants and Other Medications in Patients with Pulmonary Embolism: Results from the Lungenembolie Augsburg (LEA)
- Original Research Article
Klaus Peter Schmelzer, Dennis Freuer, Simone Fischer, Thomas M. Berghaus, Jakob Linseisen, Christa Meisinger
