Clinical Pharmacokinetics 2/2021

Jean-Baptiste Woillard, Charlotte Salmon Gandonnière, Alexandre Destere, Stephan Ehrmann, Hamid Merdji, Armelle Mathonnet, Pierre Marquet, Chantal Barin-Le Guellec

20.08.2020 | Original Research Article | Ausgabe 2/2021 Open Access

Population Pharmacokinetics of Brigatinib in Healthy Volunteers and Patients With Cancer

Neeraj Gupta, Xiaohui Wang, Elliot Offman, Marita Prohn, Narayana Narasimhan, David Kerstein, Michael J. Hanley, Karthik Venkatakrishnan

PDF-Version jetzt herunterladen Zum Volltext

17.09.2020 | Original Research Article | Ausgabe 2/2021

Physiologic Indirect Response Modeling to Describe Buprenorphine Pharmacodynamics in Newborns Treated for Neonatal Opioid Withdrawal Syndrome

Tomoyuki Mizuno, Brooks T. McPhail, Suyog Kamatkar, Scott Wexelblatt, Laura Ward, Uwe Christians, Henry T. Akinbi, Alexander A. Vinks

17.09.2020 | Original Research Article | Ausgabe 2/2021

Evaluation of Voriconazole CYP2C19 Phenotype-Guided Dose Adjustments by Physiologically Based Pharmacokinetic Modeling

Pablo Zubiaur, Lisa A. Kneller, Dolores Ochoa, Gina Mejía, Miriam Saiz-Rodríguez, Alberto M. Borobia, Dora Koller, Irene García García, Marcos Navares-Gómez, Georg Hempel, Francisco Abad-Santos

Springer Medizin

Clinical Pharmacokinetics

Ausgabe 2/2021

Inhaltsverzeichnis ( 10 Artikel )

Modernization and Strengthening of Bioequivalence Guidelines in Japan

Pharmacokinetics and Clinical Implications of Oral Semaglutide for Type 2 Diabetes Mellitus

Pharmacokinetics of Rosuvastatin: A Systematic Review of Randomised Controlled Trials in Healthy Adults

Exploration of Reduced Doses and Short-Cycle Therapy for Darunavir/Cobicistat in Patients with HIV Using Population Pharmacokinetic Modeling and Simulations

Model-Informed Precision Dosing of Everolimus: External Validation in Adult Renal Transplant Recipients

Volume of Distribution is Unaffected by Metabolic Drug–Drug Interactions

A Machine Learning Approach to Estimate the Glomerular Filtration Rate in Intensive Care Unit Patients Based on Plasma Iohexol Concentrations and Covariates

Population Pharmacokinetics of Brigatinib in Healthy Volunteers and Patients With Cancer

Physiologic Indirect Response Modeling to Describe Buprenorphine Pharmacodynamics in Newborns Treated for Neonatal Opioid Withdrawal Syndrome

Evaluation of Voriconazole CYP2C19 Phenotype-Guided Dose Adjustments by Physiologically Based Pharmacokinetic Modeling

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