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Clinical Pharmacokinetics

Ausgabe 3/2014

Inhalt (7 Artikel)

Review Article

Role of Microdialysis in Pharmacokinetics and Pharmacodynamics: Current Status and Future Directions

Francine Johansson Azeredo, Teresa Dalla Costa, Hartmut Derendorf

Original Research Article

Modelling the Sitagliptin Effect on Dipeptidyl Peptidase-4 Activity in Adults with Haematological Malignancies After Umbilical Cord Blood Haematopoietic Cell Transplantation

Nieves Vélez de Mendizábal, Robert M. Strother, Sherif S. Farag, Hal E. Broxmeyer, Steven Messina-Graham, Shripad D. Chitnis, Robert R. Bies

Original Research Article

Predictive Value of CYP3A and ABCB1 Phenotyping Probes for the Pharmacokinetics of Sunitinib: the ClearSun Study

Jacqueline S. L. Kloth, Heinz-Josef Klümpen, Huixin Yu, Karel Eechoute, Caroline F. Samer, Boen L. R. Kam, Alwin D. R. Huitema, Youssef Daali, Aeilko H. Zwinderman, Bavanthi Balakrishnar, Roelof J. Bennink, Mark Wong, Jan H. M. Schellens, Ron H. J. Mathijssen, Howard Gurney

Original Research Article

The Basel Cocktail for Simultaneous Phenotyping of Human Cytochrome P450 Isoforms in Plasma, Saliva and Dried Blood Spots

Massimiliano Donzelli, Adrian Derungs, Maria-Giovanna Serratore, Christoph Noppen, Lana Nezic, Stephan Krähenbühl, Manuel Haschke

Open Access Original Research Article

Towards Quantitation of the Effects of Renal Impairment and Probenecid Inhibition on Kidney Uptake and Efflux Transporters, Using Physiologically Based Pharmacokinetic Modelling and Simulations

Vicky Hsu, Manuela de L. T. Vieira, Ping Zhao, Lei Zhang, Jenny Huimin Zheng, Anna Nordmark, Eva Gil Berglund, Kathleen M. Giacomini, Shiew-Mei Huang