Ausgabe 4/2017
Inhalt (9 Artikel)
Open Access
Review Article
Genotypes Affecting the Pharmacokinetics of Anticancer Drugs
Daphne Bertholee, Jan Gerard Maring, André B. P. van Kuilenburg
Open Access
Review Article
A Review of Insulin Degludec/Insulin Aspart: Pharmacokinetic and Pharmacodynamic Properties and Their Implications in Clinical Use
Hanne Haahr, Edmond G. Fita, Tim Heise
Review Article
Genetic Polymorphisms Affecting the Pharmacokinetics of Antiretroviral Drugs
Andrea Calcagno, Jessica Cusato, Antonio D’Avolio, Stefano Bonora
Original Research Article
Regional Differences in Serotonin Transporter Occupancy by Escitalopram: An [11C]DASB PK-PD Study
Euitae Kim, Oliver D. Howes, Bo-Hyung Kim, Myong-Wuk Chon, Seongho Seo, Federico E. Turkheimer, Jae Sung Lee, Yun-Sang Lee, Jun Soo Kwon
Original Research Article
Physiologically Based Pharmacokinetic Prediction of Linezolid and Emtricitabine in Neonates and Infants
Peng Duan, Jeffrey W. Fisher, Kenta Yoshida, Lei Zhang, Gilbert J. Burckart, Jian Wang
Original Research Article
Impact of Demographics, Organ Impairment, Disease, Formulation, and Food on the Pharmacokinetics of the Selective S1P1 Receptor Modulator Ponesimod Based on 13 Clinical Studies
Dominik Lott, Thorsten Lehr, Jasper Dingemanse, Andreas Krause
Original Research Article
Physiologically Based Pharmacokinetic Modeling to Predict Drug–Drug Interactions with Efavirenz Involving Simultaneous Inducing and Inhibitory Effects on Cytochromes
Catia Marzolini, Rajith Rajoli, Manuel Battegay, Luigia Elzi, David Back, Marco Siccardi
Original Research Article
Population Pharmacokinetics of a Novel Once-Every 3 Months Intramuscular Formulation of Paliperidone Palmitate in Patients with Schizophrenia
Mats O. Magnusson, Mahesh N. Samtani, Elodie L. Plan, E. Niclas Jonsson, Stefaan Rossenu, An Vermeulen, Alberto Russu
Original Research Article
A Nonparametric Method to Optimize Initial Drug Dosing and Attainment of a Target Exposure Interval: Concepts and Application to Busulfan in Pediatrics
Michaël Philippe, Michael Neely, Yves Bertrand, Nathalie Bleyzac, Sylvain Goutelle