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Clinical Pharmacokinetics

Clinical Pharmacokinetics 6/2020

Ausgabe 6/2020

Inhaltsverzeichnis ( 9 Artikel )

18.04.2020 | Current Opinion | Ausgabe 6/2020 Open Access

Chloroquine for SARS-CoV-2: Implications of Its Unique Pharmacokinetic and Safety Properties

Cornelis Smit, Mariska Y. M. Peeters, John N. van den Anker, Catherijne A. J. Knibbe

04.02.2020 | Review Article | Ausgabe 6/2020

An Update on Population Pharmacokinetic Analyses of Vancomycin, Part I: In Adults

Abdullah Aljutayli, Amélie Marsot, Fahima Nekka

13.02.2020 | Review Article | Ausgabe 6/2020 Open Access

Effect of P-glycoprotein (P-gp) Inducers on Exposure of P-gp Substrates: Review of Clinical Drug–Drug Interaction Studies

Mohamed Elmeliegy, Manoli Vourvahis, Cen Guo, Diane D. Wang

08.02.2020 | Review Article | Ausgabe 6/2020

Clinical Pharmacokinetics and Pharmacodynamics of Levobupivacaine

Chantal A. A. Heppolette, Derek Brunnen, Sohail Bampoe, Peter M. Odor

05.12.2019 | Original Research Article | Ausgabe 6/2020 Open Access

A Phase I, Open-Label, Parallel-Group, Single-Dose Trial of the Pharmacokinetics, Safety, and Tolerability of Cannabidiol in Subjects with Mild to Severe Renal Impairment

Bola Tayo, Lesley Taylor, Farhad Sahebkar, Gilmour Morrison

16.12.2019 | Original Research Article | Ausgabe 6/2020

Quantitative Prediction of Interactions Mediated by Transporters and Cytochromes: Application to Organic Anion Transporting Polypeptides, Breast Cancer Resistance Protein and Cytochrome 2C8

Michel Tod, Laurent Bourguignon, Nathalie Bleyzac, Sylvain Goutelle

01.06.2020 | Original Research Article | Ausgabe 6/2020 Open Access

Unbound Plasma, Total Plasma, and Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation

Maaike A. Sikma, Erik M. Van Maarseveen, Claudine C. Hunault, Javier M. Moreno, Ed A. Van de Graaf, Johannes H. Kirkels, Marianne C. Verhaar, Jan C. Grutters, Jozef Kesecioglu, Dylan W. De Lange, Alwin D. R. Huitema

01.06.2020 | Original Research Article | Ausgabe 6/2020

A Physiologically Based Pharmacokinetic Model of Voriconazole Integrating Time-Dependent Inhibition of CYP3A4, Genetic Polymorphisms of CYP2C19 and Predictions of Drug–Drug Interactions

Xia Li, Sebastian Frechen, Daniel Moj, Thorsten Lehr, Max Taubert, Chih-hsuan Hsin, Gerd Mikus, Pertti J. Neuvonen, Klaus T. Olkkola, Teijo I. Saari, Uwe Fuhr

04.02.2020 | Original Research Article | Ausgabe 6/2020 Open Access

Effective Removal of Dabigatran by Idarucizumab or Hemodialysis: A Physiologically Based Pharmacokinetic Modeling Analysis

Laura Maria Fuhr, Nina Hanke, Bernd Meibohm, Thorsten Lehr

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