Skip to main content
Erschienen in: International Ophthalmology 11/2020

12.06.2020 | Original Paper

Clinical presentation and prognostic factors affecting surgical outcomes of secondary macular holes after retinal vein occlusions

verfasst von: Chitaranjan Mishra, Naresh Babu Kannan, Sagnik Sen, Kritika Singh, Sourav Damodaran, Piyush Kohli, Karthik Kumar, Renu P. Rajan, Girish Baliga, Kim Ramasamy

Erschienen in: International Ophthalmology | Ausgabe 11/2020

Einloggen, um Zugang zu erhalten

Abstract

Purpose

To describe clinical presentation, morphological features and surgical outcomes of macular hole (MH) secondary to retinal vein occlusion (RVO).

Method

This prospective interventional study evaluated eight eyes with atypical MH (secondary to RVO) and data regarding medical management, pars plana vitrectomy, postoperative anatomical hole closure, visual acuity improvement, morphological features of hole were noted till the last follow-up.

Results

Eight eyes with full-thickness MH in an RVO eye were followed-up for a minimum period of 3 months postoperatively. Five subjects had a RVO episode which occurred more than 6 months before the onset of the recent symptoms (Group 1; 4 branch RVO and 1 central RVO), and 3 subjects had a recent onset branch RVO within 6 months (Group 2). All FTMH cases except one showed closure at the last follow-up. Visual acuity of all eyes improved from 0.91 ± 0.57 logMAR to 0.5 ± 0.3 logMAR (p = 0.093). At baseline, visual acuities of the two groups had no significant difference. Postoperatively, group 1 holes had better visual prognosis, than Group 2 holes, further substantiated by persistence of subretinal fluid in Group 2 eyes till last follow-up. Minimum hole diameter was higher in the recent RVO group, although anatomical closure was obtained in all of these eyes. Most holes had favorable morphological hole features like raised configuration with rounded edges.

Conclusion

In the presence of favorable morphological features, secondary macular holes associated with retinal vein occlusion may show optimal outcomes after surgery. It is not clear whether acutely created holes in recent onset RVO should be operated early. Older holes may have better prognosis.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Glacet-Bernard A, Voigt M, Coscas G, Soubrane G (2007) Full-thickness macular hole following intravitreal injection of triamcinolone acetonide in central retinal vein occlusion. Retin Cases Brief Rep 1:62–64CrossRef Glacet-Bernard A, Voigt M, Coscas G, Soubrane G (2007) Full-thickness macular hole following intravitreal injection of triamcinolone acetonide in central retinal vein occlusion. Retin Cases Brief Rep 1:62–64CrossRef
2.
Zurück zum Zitat Muramatsu D, Mitsuhashi R, Iwasaki T, Goto H, Miura M (2015) Macular hole formation following intravitreal injection of ranibizumab for branch retinal vein occlusion: a case report. BMC Res Notes 8:358CrossRef Muramatsu D, Mitsuhashi R, Iwasaki T, Goto H, Miura M (2015) Macular hole formation following intravitreal injection of ranibizumab for branch retinal vein occlusion: a case report. BMC Res Notes 8:358CrossRef
3.
Zurück zum Zitat Nagpal M, Mehta V, Nagpal K (2011) Progression after intravitreal bevacizumab for hemicentral retinal vein occlusion. Case Rep Ophthal Med. Article ID 679751 Nagpal M, Mehta V, Nagpal K (2011) Progression after intravitreal bevacizumab for hemicentral retinal vein occlusion. Case Rep Ophthal Med. Article ID 679751
5.
Zurück zum Zitat Ghoraba H (2002) Types of macular holes encountered during diabetic vitrectomy. Retina 22:176–182CrossRef Ghoraba H (2002) Types of macular holes encountered during diabetic vitrectomy. Retina 22:176–182CrossRef
6.
Zurück zum Zitat Flynn HW Jr (1994) Macular hole surgery inpatients with proliferative diabetic retinopathy. Arch Ophthalmol 112:877–878CrossRef Flynn HW Jr (1994) Macular hole surgery inpatients with proliferative diabetic retinopathy. Arch Ophthalmol 112:877–878CrossRef
7.
Zurück zum Zitat Shukla D (2013) Secondary macular holes: when to jump in and when to stay out. Expert Rev Ophthalmol 8:437–446CrossRef Shukla D (2013) Secondary macular holes: when to jump in and when to stay out. Expert Rev Ophthalmol 8:437–446CrossRef
8.
Zurück zum Zitat Forooghian F, Kertes PJ, Eng KT, Agrón E, Chew EY (2010) Alterations in the intraocular cytokine milieu after intravitreal bevacizumab. Invest Ophthalmol Vis Sci 51:2388–2392CrossRef Forooghian F, Kertes PJ, Eng KT, Agrón E, Chew EY (2010) Alterations in the intraocular cytokine milieu after intravitreal bevacizumab. Invest Ophthalmol Vis Sci 51:2388–2392CrossRef
9.
Zurück zum Zitat Nakao S, Ishikawa K, Yoshida S, Kohno R, Miyazaki M, Enaida H et al (2013) Altered vascular microenvironment by bevacizumab in diabetic fibrovascular membrane. Retina 33:957–963CrossRef Nakao S, Ishikawa K, Yoshida S, Kohno R, Miyazaki M, Enaida H et al (2013) Altered vascular microenvironment by bevacizumab in diabetic fibrovascular membrane. Retina 33:957–963CrossRef
10.
Zurück zum Zitat Shukla D, Rajendran A, Kim R (2006) Macular hole formation and spontaneous closure after vitrectomy for central retinal vein occlusion. Graefe’s Arch Clin Exp Ophthalmol 244:1350–1352CrossRef Shukla D, Rajendran A, Kim R (2006) Macular hole formation and spontaneous closure after vitrectomy for central retinal vein occlusion. Graefe’s Arch Clin Exp Ophthalmol 244:1350–1352CrossRef
11.
Zurück zum Zitat Liang X, Liu W (2019) Characteristics and risk factors for spontaneous closure of idiopathic full-thickness macular hole. J Ophthalmol. Article ID 4793764 Liang X, Liu W (2019) Characteristics and risk factors for spontaneous closure of idiopathic full-thickness macular hole. J Ophthalmol. Article ID 4793764
12.
Zurück zum Zitat Huang J, Liu X, Wu Z et al (2009) Classification of full-thickness traumatic macular holes by optical coherence tomography. Retina 29:340–348CrossRef Huang J, Liu X, Wu Z et al (2009) Classification of full-thickness traumatic macular holes by optical coherence tomography. Retina 29:340–348CrossRef
13.
Zurück zum Zitat Brockmann T, Steger C, Weger M, Wedrich A, Haas A (2013) Risk assessment of idiopathic macular holes undergoing vitrectomy with dye-assisted internal limiting membrane peeling. Retina 33:1132–1136CrossRef Brockmann T, Steger C, Weger M, Wedrich A, Haas A (2013) Risk assessment of idiopathic macular holes undergoing vitrectomy with dye-assisted internal limiting membrane peeling. Retina 33:1132–1136CrossRef
14.
Zurück zum Zitat Sou R, Kusaka S, Ohji M, Gomi F, Ikuno Y, Tano Y (2003) Optical coherence tomographic evaluation of a surgically treated traumatic macular hole secondary to Nd:YAG laser injury. Am J Ophthalmol 135:537–539CrossRef Sou R, Kusaka S, Ohji M, Gomi F, Ikuno Y, Tano Y (2003) Optical coherence tomographic evaluation of a surgically treated traumatic macular hole secondary to Nd:YAG laser injury. Am J Ophthalmol 135:537–539CrossRef
15.
Zurück zum Zitat Shukla D (2011) Evolution and management of macular hole secondary to type 2 idiopathic macular telangiectasia. Eye 25:532–533CrossRef Shukla D (2011) Evolution and management of macular hole secondary to type 2 idiopathic macular telangiectasia. Eye 25:532–533CrossRef
16.
Zurück zum Zitat Shukla D, Kalliath J, Tandon M, Vijayakumar B (2012) Vitrectomy for optic disk pit with macular schisis and outer retinal dehiscence. Retina 32:1337–1342CrossRef Shukla D, Kalliath J, Tandon M, Vijayakumar B (2012) Vitrectomy for optic disk pit with macular schisis and outer retinal dehiscence. Retina 32:1337–1342CrossRef
17.
Zurück zum Zitat O’Driscoll AM, Goble RR, Kirkby GR (2001) Vitrectomy for retinal detachments with both peripheral retinal breaks and macular holes: an assessment of outcome and the status of the macular hole. Retina 21:221–225CrossRef O’Driscoll AM, Goble RR, Kirkby GR (2001) Vitrectomy for retinal detachments with both peripheral retinal breaks and macular holes: an assessment of outcome and the status of the macular hole. Retina 21:221–225CrossRef
18.
Zurück zum Zitat Ryan EH Jr, Bramante CA, Mittra RA et al (2011) Management of rhegmatogenous retinal detachment with coexistent macular hole in the era of internal limiting membrane peeling. Am J Ophthalmol 152:815–819CrossRef Ryan EH Jr, Bramante CA, Mittra RA et al (2011) Management of rhegmatogenous retinal detachment with coexistent macular hole in the era of internal limiting membrane peeling. Am J Ophthalmol 152:815–819CrossRef
19.
Zurück zum Zitat Shukla D, Kalliath J, Srinivasan K et al (2013) Management of rhegmatogenous retinal detachment with coexisting macular hole: a comparison of vitrectomy with and without internal limiting membrane peeling. Retina 33:571–578CrossRef Shukla D, Kalliath J, Srinivasan K et al (2013) Management of rhegmatogenous retinal detachment with coexisting macular hole: a comparison of vitrectomy with and without internal limiting membrane peeling. Retina 33:571–578CrossRef
20.
Zurück zum Zitat Bhatnagar P, Kaiser PK, Smith SD, Meisler DM, Lewis H, Sears JE (2007) Reopening of previously closed macular holes after cataract extraction. Am J Ophthalmol 144:252–259CrossRef Bhatnagar P, Kaiser PK, Smith SD, Meisler DM, Lewis H, Sears JE (2007) Reopening of previously closed macular holes after cataract extraction. Am J Ophthalmol 144:252–259CrossRef
21.
Zurück zum Zitat Halkiadakis I, Pantelia E, Giannakopoulos N, Koutsandrea C, Markomichelakis NN (2003) Macular hole closure after peribulbar steroid injection. Am J Ophthalmol 136:1165–1167CrossRef Halkiadakis I, Pantelia E, Giannakopoulos N, Koutsandrea C, Markomichelakis NN (2003) Macular hole closure after peribulbar steroid injection. Am J Ophthalmol 136:1165–1167CrossRef
22.
Zurück zum Zitat Shukla D, Dhawan A (2011) Pharmacotherapeutic closure of a uveitic macular hole persisting after vitrectomy. Indian J Ophthalmol 59:335–336CrossRef Shukla D, Dhawan A (2011) Pharmacotherapeutic closure of a uveitic macular hole persisting after vitrectomy. Indian J Ophthalmol 59:335–336CrossRef
23.
Zurück zum Zitat Zinkernagel MS, Groppe M, Maclaren RE (2013) Macular hole surgery in patients with end-stage choroideremia. Ophthalmology 120:1592–1596CrossRef Zinkernagel MS, Groppe M, Maclaren RE (2013) Macular hole surgery in patients with end-stage choroideremia. Ophthalmology 120:1592–1596CrossRef
24.
Zurück zum Zitat Shukla D, Naresh KB, Rajendran A, Kim R (2006) Macular hole secondary to X-linked retinoschisis. Eye 20:1459–1461CrossRef Shukla D, Naresh KB, Rajendran A, Kim R (2006) Macular hole secondary to X-linked retinoschisis. Eye 20:1459–1461CrossRef
25.
Zurück zum Zitat Park DH, Kim IT (2010) Long-term effects of vitrectomy and internal limiting membrane peeling for macular edema secondary to central retinal vein occlusion and hemiretinal vein occlusion. Retina 30:117–124CrossRef Park DH, Kim IT (2010) Long-term effects of vitrectomy and internal limiting membrane peeling for macular edema secondary to central retinal vein occlusion and hemiretinal vein occlusion. Retina 30:117–124CrossRef
26.
Zurück zum Zitat Yamamoto T, Hitani K, Tsukahara I et al (2003) Early postoperative retinal thickness changes and complications after vitrectomy for diabetic macular edema. Am J Ophthalmol 135:14–19CrossRef Yamamoto T, Hitani K, Tsukahara I et al (2003) Early postoperative retinal thickness changes and complications after vitrectomy for diabetic macular edema. Am J Ophthalmol 135:14–19CrossRef
27.
Zurück zum Zitat Mandelcorn MS, Mandelcorn E, Guan K, Adatia FA (2007) Surgical macular decompression for macular edema in retinal vein occlusion. Can J Ophthalmol 42:116–122CrossRef Mandelcorn MS, Mandelcorn E, Guan K, Adatia FA (2007) Surgical macular decompression for macular edema in retinal vein occlusion. Can J Ophthalmol 42:116–122CrossRef
28.
Zurück zum Zitat Gandorfer A, Messmer EM, Ulbig MW, Kampik A (2000) Resolution of diabetic macular edema after surgical removal of the posterior hyaloid and the inner limiting membrane. Retina 20:126–133CrossRef Gandorfer A, Messmer EM, Ulbig MW, Kampik A (2000) Resolution of diabetic macular edema after surgical removal of the posterior hyaloid and the inner limiting membrane. Retina 20:126–133CrossRef
29.
Zurück zum Zitat Hayreh SS, Zimmerman MB, Podhajsky P (1994) Incidence of various types of retinal vein occlusion and their recurrence and demographic characteristics. Am J Ophthalmol 117:429–441CrossRef Hayreh SS, Zimmerman MB, Podhajsky P (1994) Incidence of various types of retinal vein occlusion and their recurrence and demographic characteristics. Am J Ophthalmol 117:429–441CrossRef
Metadaten
Titel
Clinical presentation and prognostic factors affecting surgical outcomes of secondary macular holes after retinal vein occlusions
verfasst von
Chitaranjan Mishra
Naresh Babu Kannan
Sagnik Sen
Kritika Singh
Sourav Damodaran
Piyush Kohli
Karthik Kumar
Renu P. Rajan
Girish Baliga
Kim Ramasamy
Publikationsdatum
12.06.2020
Verlag
Springer Netherlands
Erschienen in
International Ophthalmology / Ausgabe 11/2020
Print ISSN: 0165-5701
Elektronische ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-020-01465-7

Weitere Artikel der Ausgabe 11/2020

International Ophthalmology 11/2020 Zur Ausgabe

Neu im Fachgebiet Augenheilkunde

Open Access 22.02.2024 | Peeling | Originalien

Selektive Vitalfarbstoffe in der Makulachirurgie

Erhöhen sie die Wahrscheinlichkeit der intraoperativen ILM-Identifizierung auch bei einem erfahrenen Operateur?

Update Augenheilkunde

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.