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Erschienen in:

15.01.2020

Clinical research tools in pediatric oncology: challenges and opportunities

verfasst von: Teresa de Rojas, Anouk Neven, Alexander J. Towbin, Fernando Carceller, Francisco Bautista, David Riedl, Samantha Sodergren, Anne-Sophie Darlington, Ana Fernandez-Teijeiro, Lucas Moreno

Erschienen in: Cancer and Metastasis Reviews | Ausgabe 1/2020

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Abstract

Survival for childhood cancers has improved significantly over the last decades. However, patient outcomes have plateaued over the last decade for difficult-to-treat diseases. With high cure rates, decreasing long-term toxicities and sequelae remains crucial. Since many advances in childhood cancer research come from the adult oncology world, one of the key areas is improving the adaptation of tools that are essential for clinical trial conduct that were developed for adults into pediatrics. These include tools to evaluate toxicity, quality of life, radiological response, statistical methodology, or indicators of cancer care quality. In this review, we present ongoing international efforts to validate and adapt these tools for children and adolescents and discuss remaining challenges. These efforts will hopefully accelerate and improve the quality of pediatric oncology research in the upcoming years.

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Titel: Clinical research tools in pediatric oncology: challenges and opportunities
verfasst von: Teresa de Rojas
Anouk Neven
Alexander J. Towbin
Fernando Carceller
Francisco Bautista
David Riedl
Samantha Sodergren
Anne-Sophie Darlington
Ana Fernandez-Teijeiro
Lucas Moreno
Publikationsdatum: 15.01.2020
Verlag: Springer US
Erschienen in: Cancer and Metastasis Reviews / Ausgabe 1/2020
Print ISSN: 0167-7659
Elektronische ISSN: 1573-7233
DOI: https://doi.org/10.1007/s10555-020-09856-z

Neu im Fachgebiet Onkologie

25.04.2024 | Nierenkarzinom | Nachrichten

Springer Medizin

Clinical research tools in pediatric oncology: challenges and opportunities

Abstract

Neu im Fachgebiet Onkologie

Adjuvante Immuntherapie verlängert Leben bei RCC

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

Bei Senioren mit Prostatakarzinom auf Anämie achten!

ICI-Therapie in der Schwangerschaft wird gut toleriert

Update Onkologie

Springer Medizin

Abstract

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