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Clinical Reviews in Allergy & Immunology

Clinical Reviews in Allergy & Immunology OnlineFirst articles

07.02.2020

Using Baseline and Peak Serum Tryptase Levels to Diagnose Anaphylaxis: a Review

The diagnosis of anaphylaxis relies on a suggestive clinical history after exposure to a potential triggering factor. Serum tryptase concentrations increase on degranulation of mast cells and therefore serum tryptase levels are measured to …

24.01.2020

The Current State of Biologic Therapies for Treatment of Refractory Asthma

Asthma is a heterogeneous disease, with the immune processes behind the chronic inflammation underlying this disorder differing between the various identified asthma endotypes. In addition to heterogeneity in underlying disease pathophysiology …

09.01.2020

Targeted Anti-IL-5 Therapies and Future Therapeutics for Hypereosinophilic Syndrome and Rare Eosinophilic Conditions

Eosinophilic inflammation is a component of many atopic diseases such as asthma, and biologics targeting eosinophils have been shown to be effective in subsets of these patients. However, there also are conditions in which eosinophils are the key …

13.12.2019

Eczema Herpeticum: Clinical and Pathophysiological Aspects

Atopic dermatitis (AD) is the most common chronic inflammatory skin disease in the world. AD is a complex pathology mainly characterized by an impaired skin barrier, immune response dysfunction, and unbalanced skin microbiota. Moreover, AD …

27.11.2019

Innate-like Lymphocytes and Innate Lymphoid Cells in Asthma

Asthma is a chronic pulmonary disease, highly associated with immune disorders. The typical symptoms of asthma include airway hyperresponsiveness (AHR), airway remodeling, mucus overproduction, and airflow limitation. The etiology of asthma is …

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Über diese Zeitschrift

The development of clinical allergy as a discipline of scientific medicine has, until recently, lagged behind that of other subspecialties in internal medicine and pediatrics. The discovery of immunoglobulin E, the development of standardized protocols for allergy skin testing and challenge procedures, and concurrent advances in cell biology have all led to a major thrust by new data in changing the approach to the clinical management of allergic disease. The object of this journal is to publish scholarly review papers, with each issue devoted to a single theme, in an attempt to provide comprehensive treatment of a subject of critical importance to allergists. The journal publishes both experimental papers and comprehensive treatises placing new data in perspective. The ultimate objective is to help improve the care and management of patients with allergic disease.

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