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Clinical Reviews in Allergy & Immunology

Clinical Reviews in Allergy & Immunology OnlineFirst articles

07.10.2020 | Review Article

Use of Ultraviolet Blood Irradiation Against Viral Infections

Ultraviolet blood irradiation (UBI) was used with success in the 1930s and 1940s for a variety of diseases. Despite the success, the lack of understanding of the detailed mechanisms of actions, and the achievements of antibiotics, phased off the …


Equine Hypersensitivity: the Dark Horse of Allergy

A significant amount of medical literature has been published on the prevalence and treatment modalities of allergies to common household pets like dogs and cats. Although sensitization rates to horses are high in many urban areas, allergies to …


Are Physicochemical Properties Shaping the Allergenic Potency of Plant Allergens?

This review searched for published evidence that could explain how different physicochemical properties impact on the allergenicity of food proteins and if their effects would follow specific patterns among distinct protein families. Owing to the …


Clinical Manifestations and Management of Pediatric Behçet’s Disease

Behçet’s disease (BD) is a chronic, vasculitic disorder affecting all sizes of vessels. The disease rarely onsets at childhood and an early diagnosis is often challenging. Oral ulceration and fever of unknown cause are common initial …


A Review of Neutrophil Extracellular Traps (NETs) in Disease: Potential Anti-NETs Therapeutics

Activated neutrophils release neutrophil extracellular traps (NETs) in response to a variety of stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of intracellular granule components that function by capturing and …

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The development of clinical allergy as a discipline of scientific medicine has, until recently, lagged behind that of other subspecialties in internal medicine and pediatrics. The discovery of immunoglobulin E, the development of standardized protocols for allergy skin testing and challenge procedures, and concurrent advances in cell biology have all led to a major thrust by new data in changing the approach to the clinical management of allergic disease. The object of this journal is to publish scholarly review papers, with each issue devoted to a single theme, in an attempt to provide comprehensive treatment of a subject of critical importance to allergists. The journal publishes both experimental papers and comprehensive treatises placing new data in perspective. The ultimate objective is to help improve the care and management of patients with allergic disease.

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