Background
Methods
Patients
Statistical analysis
Results
Demographic characteristics
UCD | MCD | P | |
---|---|---|---|
Age (mean, years)
| 30.44 ± 8.00 | 41.56 ± 13.50 | 0.004 |
Gender
| |||
Male | 8/50% | 11/34.4% | 0.2967 |
Female | 8/50% | 21/65.6% | |
Pathological type
| |||
Hyaline vascular | 3/18.75% | 16/50% | |
Plasma cell | 12/75% | 12/37.5% | 0.049 |
Mixed | 1/6.25% | 4/12.5% | |
Non-symptomatic
| 8/50% | 1/3.1% | <0.001 |
Fever
| 0 | 16/50% | <0.001 |
Pleural effusion
| 2/12.5% | 13/40.6% | 0.0475 |
Hepatomegaly and/or splenomegaly
| 0 | 16/50% | <0.001 |
Anemia
| 3/18.8% | 15/46.9% | 0.0578 |
Hemoglobin (g/l)
| 133.13 ± 29.70 | 108.66 ± 26.60 | 0.0059 |
Platelet (×10
9
/l)
| |||
>300 × 10
9
/l | 4/25% | 12/37.5% | 0.6785 |
<100 × 10
9
/l | 1/8.3% | 2/10% | |
Hypoalbuminia
| 4/25% | 22/68.8% | 0.0041 |
Elevation of serum LDH
‡
| 5/30% | 5/16.1% | 0.6731 |
HIV-Ab
| |||
Not done | 0 | 6/18.75% | |
Negative | 16/100% | 26/100% (n = 26) | 1 |
Chemotherapy cases
| 0 | 28/87.5% | <0.001 |
Outcomes
| |||
Cured | 16/100% | 0 | |
Improved | 0 | 18/56.3% | |
Stable | 0 | 7/21.9% | <0.001 |
Died | 0 | 3/9.4% | |
Lost follow-up | 0 | 4/12.5% |
Clinical and radiological manifestations
Chest CT characters | n/% |
---|---|
UCDs (n = 16)
| |
Solitary mass (n = 16,100%)
| |
Location
| |
Mediastinum
| 11/68.75% |
Lung hilum
| 3/18.75% |
Intrapulmonary fissure
| 1/6.25% |
Lung
| 1/6.25% |
Size
| (113.56 ± 81.31) cm3 [(20–336) cm3] |
Punctate calcification in the mass
| 5/31.25% |
Enhancement in the contrast-enhanced CT (n = 14)
Ф
| |
Pattern
| |
Homogeneous
| 12/85.71% |
Heterogeneous
| 2/14.29% |
Degree
| |
High
| 13/92.86% |
Moderate
| 1/7.14% |
Pleural effusion
| 2/14.29% |
MCDs (n = 32)
| |
Lymphadenopathy
| |
Location
| |
Diffuse lymphadenopathy in the hilum and/or mediastinum
| 32/100% |
Superficial lymphadenopathy
| 20/62.5% |
Cervical LNs
| 20/62.5% |
Superclavicular LNs
| 4/12.5% |
Axillary LNs
| 12/37.5% |
Diffuse parenchymal lung disease
| 14/43.75% |
Multiple nodules in different size
| 6/18.75% |
Multiple patchy infiltrates
| 6/18.75% |
GGO
| 5/15.63% |
LIP-like pattern
| 3/9.38% |
Consolidation
| 3/9.38% |
Bronchiolitis obliterans
| 1/3.12% |
Mass
| 3/9.38% |
Mediastinal mass
| 2/6.25% |
Hilar mass
| 1/3.12% |
Pleural effusion
| 13/40.6% |
Laboratory tests
Pathological features
UCD (n = 16) | MCD (n = 32) | |
---|---|---|
Thoracic surgery
| ||
Open thoracic surgery
| 16/100% | 0 |
VATS
ξ
| 1/16.67% | 8/25% |
Abdominal surgery
| 0 | 1/3.12% |
Superficial LN biopsy
| 0 | 21/65.6% |
Cervical LN
| 0 | 9/28.13% |
Axillary LN
| 0 | 6/18.75% |
Supratrochlear LN
| 0 | 1/3.12% |
Percutaneous lung biopsy
| 0 | 2/6.25% |