Erschienen in:
01.11.2010 | Case Report
Coexistence of chronic myeloid leukemia and pulmonary plasmacytoma mimicking primary lung cancer
verfasst von:
Hee Jin Kim, Moon Jin Kim, Min Jeong Lee, Jong-Hwa Ahn, Ho-Su Kim, In-Suk Kim, Jong Sil Lee, Gyeong-Won Lee
Erschienen in:
International Journal of Hematology
|
Ausgabe 4/2010
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Abstract
A 61-year-old man was diagnosed with the simultaneous occurrence of chronic myeloid leukemia (CML) and infiltrative intrathoracic plasmacytoma, radiologically mimicking bronchogenic carcinoma. Following the administration of imatinib mesylate (IM; 400 mg/day), both hematologic and partial cytogenetic remission of CML were achieved. However, the pulmonary plasmacytoma was persistently aggravated. High-dose dexamethasone was added to the IM therapy because the patient refused radiotherapy to control the aggravated pulmonary plasmacytoma. Finally, he died due to pneumonia and multi-organ failure during concurrent administration of IM and high-dose dexamethasone.