Erschienen in:
23.05.2020 | Sleep Breathing Physiology and Disorders • Review
Cognitive impairment in obstructive sleep apnea syndrome: a descriptive review
verfasst von:
Mina Caporale, Rosanna Palmeri, Francesco Corallo, Nunzio Muscarà, Laura Romeo, Alessia Bramanti, Silvia Marino, Viviana Lo Buono
Erschienen in:
Sleep and Breathing
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Ausgabe 1/2021
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Abstract
Purpose
Obstructive sleep apnea syndrome is a clinical sleep disorder defined by total or partial airflow restraint during sleep that results in fragmented sleep and hypoxemia, impacting negatively with cognitive functioning. This review was conducted on studies investigating structural brain alteration and cognitive impairment in obstructive sleep apnea syndrome.
Method
We searched on PubMed databases and screening references of included studies and review articles for additional citations. From initial 190 publications, only 17 met search criteria and described the cognitive impairment in obstructive sleep apnea syndrome.
Results
Findings showed that patients with this syndrome had worse performance than healthy controls in attention, memory, and executive functions, showing specific neuroanathomical features. Cognitive impairment is also related to the severity of pathology. Treatment could improve certain cognitive aspects.
Conclusions
Cognitive deficits seem to be mainly attributable to decreased daytime vigilance and nocturnal hypoxemia.