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Neurocritical Care

Erschienen in:

28.03.2017 | Original Article

Cold Blooded: Evaluating Brain Temperature by MRI During Surface Cooling of Human Subjects

verfasst von: Eric J. Curran, Daniel L. Wolfson, Richard Watts, Kalev Freeman

Erschienen in: Neurocritical Care | Ausgabe 2/2017

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Abstract

Background

Targeted temperature management (TTM) confers neurological and survival benefits for post-cardiac arrest patients with return of spontaneous circulation (ROSC) who remain comatose. Specialized equipment for induction of hypothermia is not available in the prehospital setting, and there are no reliable methods for emergency medical services personnel to initiate TTM. We hypothesized that the application of surface cooling elements to the neck will decrease brain temperature and act as initiators of TTM.

Methods

Magnetic resonance (MR) spectroscopy was used to evaluate the effect of a carotid surface cooling element on brain temperature in healthy adults.

Results

Six individuals completed this study. We measured a temperature drop of 0.69 ± 0.38 °C (95% CI) in the cortex of the brain following the application of the cooling element. Application of a room temperature element also caused a measurable decrease in brain temperature of 0.66 ± 0.41 °C (95% CI) which may be attributable to baroreceptor activation.

Conclusion

The application of surface cooling elements to the neck decreased brain temperature and may serve as a method to initiate TTM in the prehospital setting.

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Titel: Cold Blooded: Evaluating Brain Temperature by MRI During Surface Cooling of Human Subjects
verfasst von: Eric J. Curran
Daniel L. Wolfson
Richard Watts
Kalev Freeman
Publikationsdatum: 28.03.2017
Verlag: Springer US
Erschienen in: Neurocritical Care / Ausgabe 2/2017
Print ISSN: 1541-6933
Elektronische ISSN: 1556-0961
DOI: https://doi.org/10.1007/s12028-017-0389-4

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Cold Blooded: Evaluating Brain Temperature by MRI During Surface Cooling of Human Subjects

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