17.06.2022 | GI Image
Colonic Malakoplakia with Retroperitoneal Extension Mimicking Advanced Colon Cancer
verfasst von:
Yu-Chun Ma, Song-Wei Wang, Kung-Chao Chang
Erschienen in:
Journal of Gastrointestinal Surgery
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Ausgabe 11/2022
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Excerpt
Malakoplakia is an uncommon lesion characterized by chronic granulomatous inflammatory with dense histiocytic infiltration, and most commonly affects the gastrointestinal and genitourinary tracts, though any organ of the body can occur. Malakoplakia of the gastrointestinal tract most frequently involve the rectum, sigmoid colon, and right colon, and the infiltrating histiocytes carry the ability to extend into peritoneal and retroperitoneal cavities, which usually simulates an advanced cancer clinically or radiologically and leads to an unnecessary operation.
1 However, with correct pathologic diagnosis and appropriate antibiotic therapy, mass-forming malakoplakia frequently responds to treatment and regresses well. …