Skip to main content
Erschienen in:

05.08.2021 | Original Article

Combination of two desensitizing protocols to control dentin hypersensitivity in non-carious lesions: a randomized, double-blind clinical trial

verfasst von: Antonia Patricia Oliveira Barros, Cristiane de Melo Alencar, Alexandra de Melo Pingarilho Carneiro, Danielle da Silva Pompeu, Gabriela Monteiro Barbosa, Jesuína Lamartine Nogueira Araújo, Cecy Martins Silva

Erschienen in: Clinical Oral Investigations | Ausgabe 2/2022

Einloggen, um Zugang zu erhalten

Abstract

Objectives

This study evaluated the effect of photobiomodulation (PBM) combined with 8% strontium acetate (SA8%) in the treatment of dentin hypersensitivity (DH) in non-carious lesions and analyzed the risk factors with the patient’s quality of life.

Methods

Eighty teeth with DH were randomly allocated into four treatment groups (n = 20): G1, PBM imitation + toothpaste with no active ingredient; G2, PBM imitation + toothpaste with SA8%; G3, PBM + toothpaste without the active ingredient; and G4, PBM + toothpaste with SA8%. Participants were provided with a questionnaire on the experience of dentin hypersensitivity (QEDH) to assess the impact of desensitizing treatment on health-related quality of life (HRQL). Friedman and Kruskal–Wallis tests were used for intra- and intergroup comparisons, and Wilcoxon and Mann–Whitney tests were used to analyze HRQL. All analyses used significance levels of 5%.

Results

Intergroup comparisons revealed a significant difference (p < 0.05); G4 had the best response in terms of HD reduction in G4 compared to the other groups on the 7th day of assessment (T3). Only G4 showed a statistically significant difference (p < 0.05) in the reduction of EDH for intragroup analysis.

Conclusion

The combination of therapies was more effective in reducing DH than the isolated use of these strategies.

Clinical relevance

The combination of therapies is effective in the treatment of DH.
Literatur
1.
Zurück zum Zitat Suchetha A, Keshava Prasad BS, Apoorva SM, Lakshmi P (2013) Dentinal hypersensitivity- a review. Indian J Dent Sci 5(2):112–116 Suchetha A, Keshava Prasad BS, Apoorva SM, Lakshmi P (2013) Dentinal hypersensitivity- a review. Indian J Dent Sci 5(2):112–116
2.
Zurück zum Zitat Patil SA, Naik BD, Suma R (2015) Evaluation of three different agents for in-office treatment of dentinal hypersensitivity: a controlled clinical study. Indian J Dent Res 26(1):38–42CrossRef Patil SA, Naik BD, Suma R (2015) Evaluation of three different agents for in-office treatment of dentinal hypersensitivity: a controlled clinical study. Indian J Dent Res 26(1):38–42CrossRef
3.
Zurück zum Zitat Addy M (1992) Aspectos clínicos da hipersensibilidade à dentina. Proc Finn Dent Soc 88(1):407–412 Addy M (1992) Aspectos clínicos da hipersensibilidade à dentina. Proc Finn Dent Soc 88(1):407–412
4.
Zurück zum Zitat Brännström M (1966) Sensitivity of dentine. Oral Surg Oral Med Oral Pathol 21(4):517–526CrossRef Brännström M (1966) Sensitivity of dentine. Oral Surg Oral Med Oral Pathol 21(4):517–526CrossRef
5.
Zurück zum Zitat Shibukawa Y, Sato M, Kimura M, Sobhan U, Shimada M, Nishiyama A, Katakura A, Ichinohe T, Tazaki M, Shibukawa Y (2015) Odontoblasts as sensory receptors: transient receptor potential channels, pannexin-1, and ionotropic ATP receptors mediate intercellular odontoblast-neuron signal transduction. Pflugers Arch Eur J Physio 467:843–863. https://doi.org/10.1007/s00424-014-1551-xCrossRef Shibukawa Y, Sato M, Kimura M, Sobhan U, Shimada M, Nishiyama A, Katakura A, Ichinohe T, Tazaki M, Shibukawa Y (2015) Odontoblasts as sensory receptors: transient receptor potential channels, pannexin-1, and ionotropic ATP receptors mediate intercellular odontoblast-neuron signal transduction. Pflugers Arch Eur J Physio 467:843–863. https://​doi.​org/​10.​1007/​s00424-014-1551-xCrossRef
7.
Zurück zum Zitat Kopycka-Kedzierawski DT, Meyerowitz C, Litaker MS, Heft MW, Tasgaonkar N, Day MR, Porter-Williams A, Gordan VV, Yardic RL, Lawhorn TM, Gilbert GH, National Dental PBRN Collaborative Group (2017) Management of dentin hypersensitivity by practitioners in the National Dental Practice-Based Research Network. J Am Dent Assoc 148:728–736CrossRef Kopycka-Kedzierawski DT, Meyerowitz C, Litaker MS, Heft MW, Tasgaonkar N, Day MR, Porter-Williams A, Gordan VV, Yardic RL, Lawhorn TM, Gilbert GH, National Dental PBRN Collaborative Group (2017) Management of dentin hypersensitivity by practitioners in the National Dental Practice-Based Research Network. J Am Dent Assoc 148:728–736CrossRef
9.
Zurück zum Zitat Lopes AO, Paula Eduardo C, Aranha ACC (2017) Evaluation of different treatment protocols for dentin hypersensitivity: an 18-month randomized clinical trial. Lasers Med Sci 32(5):1023–1030CrossRef Lopes AO, Paula Eduardo C, Aranha ACC (2017) Evaluation of different treatment protocols for dentin hypersensitivity: an 18-month randomized clinical trial. Lasers Med Sci 32(5):1023–1030CrossRef
11.
Zurück zum Zitat Parkinson CR, Willson RJ (2010) A comparative in vitro study investigating the occlusion and mineralization properties of commercial toothpastes in a four-day dentin disc model. J Clin Dent 22(3):74–81 Parkinson CR, Willson RJ (2010) A comparative in vitro study investigating the occlusion and mineralization properties of commercial toothpastes in a four-day dentin disc model. J Clin Dent 22(3):74–81
12.
Zurück zum Zitat Grünberg C, Bauer F, Crispin A, Jakob M, Hickel R, Draenert ME (2017) Effectiveness of dentifrices with new formulations for the treatment of dentin hypersensitivity - a meta-analysis. Am J Dent 30(4):221–226PubMed Grünberg C, Bauer F, Crispin A, Jakob M, Hickel R, Draenert ME (2017) Effectiveness of dentifrices with new formulations for the treatment of dentin hypersensitivity - a meta-analysis. Am J Dent 30(4):221–226PubMed
16.
Zurück zum Zitat Ortiz MIG, Melo Alencar C, Paula BLF, Alves EB, Araújo JLN, Silva CM (2019) Effect of the casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF) and photobiomodulation (PBM) on dental hypersensitivity: a randomized controlled clinical trial. PloS one 14(12):e0225501CrossRef Ortiz MIG, Melo Alencar C, Paula BLF, Alves EB, Araújo JLN, Silva CM (2019) Effect of the casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF) and photobiomodulation (PBM) on dental hypersensitivity: a randomized controlled clinical trial. PloS one 14(12):e0225501CrossRef
18.
Zurück zum Zitat Pandis N, Chung B, Scherer RW, Elbourne D, Altman DG (2019) CONSORT 2010 statement: extension checklist for reporting within person randomised trials. Bri J Dermatol 180(3):534–552CrossRef Pandis N, Chung B, Scherer RW, Elbourne D, Altman DG (2019) CONSORT 2010 statement: extension checklist for reporting within person randomised trials. Bri J Dermatol 180(3):534–552CrossRef
19.
Zurück zum Zitat World Medical Association (2013) World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. J Am Med Assoc 310(20):2191CrossRef World Medical Association (2013) World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. J Am Med Assoc 310(20):2191CrossRef
21.
Zurück zum Zitat Freitas SDS, Sousa LLA, Moita Neto JM, Mendes RF, Prado Junior RR (2015) Dentin hypersensitivity treatment of non-carious cervical lesions–a single-blind, split-mouth study. Braz oral res 29(1):1–6CrossRef Freitas SDS, Sousa LLA, Moita Neto JM, Mendes RF, Prado Junior RR (2015) Dentin hypersensitivity treatment of non-carious cervical lesions–a single-blind, split-mouth study. Braz oral res 29(1):1–6CrossRef
22.
Zurück zum Zitat Rees JS, Jin LJ, Lam S, Kudanowska I, Vowles R (2003) The prevalence of dentine hypersensitivity in a hospital clinic population in Hong Kong. J Dent 31(7):453–461CrossRef Rees JS, Jin LJ, Lam S, Kudanowska I, Vowles R (2003) The prevalence of dentine hypersensitivity in a hospital clinic population in Hong Kong. J Dent 31(7):453–461CrossRef
23.
Zurück zum Zitat Chiarotto A, Maxwell LJ, Ostelo RW, Boers M, Tugwell P, Terwee CB (2019) Measurement properties of visual analogue scale, numeric rating scale, and pain severity subscale of the brief pain inventory in patients with low back pain: a systematic review. J of Pain 20(3):245–263CrossRef Chiarotto A, Maxwell LJ, Ostelo RW, Boers M, Tugwell P, Terwee CB (2019) Measurement properties of visual analogue scale, numeric rating scale, and pain severity subscale of the brief pain inventory in patients with low back pain: a systematic review. J of Pain 20(3):245–263CrossRef
26.
Zurück zum Zitat Bartold PM (2006) Dentinal hypersensitivity: a review. Aust Dent J 51(3):212–218CrossRef Bartold PM (2006) Dentinal hypersensitivity: a review. Aust Dent J 51(3):212–218CrossRef
27.
Zurück zum Zitat Porto IC, Andrade AK, Montes MA (2009) Diagnosis and treatment of dentinal hypersensitivity. J Oral Sci 51(3):323–332CrossRef Porto IC, Andrade AK, Montes MA (2009) Diagnosis and treatment of dentinal hypersensitivity. J Oral Sci 51(3):323–332CrossRef
28.
Zurück zum Zitat Markowitz K (2009) The original desensitizers: strontium and potassium salts. J Clin Dent 20(5):145–51PubMed Markowitz K (2009) The original desensitizers: strontium and potassium salts. J Clin Dent 20(5):145–51PubMed
29.
Zurück zum Zitat Mason S, Hughes N, Layer T (2009) Considerations for the development of over-the-counter dentifrices for the treatment and relief of dentin sensitivity. J clin dente 20(5):167–173 Mason S, Hughes N, Layer T (2009) Considerations for the development of over-the-counter dentifrices for the treatment and relief of dentin sensitivity. J clin dente 20(5):167–173
30.
Zurück zum Zitat West NX, Addy M, Jackson RJ, Ridge D (1997) Dentine hypersensitivity and the placebo response. A comparison of the effect of strontium acetate, potassium nitrate and fluoride toothpastes. J Clin Periodontol 24(4):209–15CrossRef West NX, Addy M, Jackson RJ, Ridge D (1997) Dentine hypersensitivity and the placebo response. A comparison of the effect of strontium acetate, potassium nitrate and fluoride toothpastes. J Clin Periodontol 24(4):209–15CrossRef
31.
Zurück zum Zitat Yu X, Liang B, Jin M, Fu X, Hannig B (2010) Comparative in vivo study on the desensitizing efficacy of dentin desensitizers and one-bottle self-etching adhesives. Operat Dent 35(3):279–286CrossRef Yu X, Liang B, Jin M, Fu X, Hannig B (2010) Comparative in vivo study on the desensitizing efficacy of dentin desensitizers and one-bottle self-etching adhesives. Operat Dent 35(3):279–286CrossRef
33.
Zurück zum Zitat Karu T (1998) The science of low-power laser therapy, 1st edn. Gordon and Breach Science Publishers, New Delhi Karu T (1998) The science of low-power laser therapy, 1st edn. Gordon and Breach Science Publishers, New Delhi
34.
Zurück zum Zitat Zang P, Shaw D (2016) A randomized clinical study to evaluate the efficacy of an 8% (w/w) strontium acetate dentifrice in providing relief from dentinal hypersensitivity. J Clin Dent 27(4):91–96PubMed Zang P, Shaw D (2016) A randomized clinical study to evaluate the efficacy of an 8% (w/w) strontium acetate dentifrice in providing relief from dentinal hypersensitivity. J Clin Dent 27(4):91–96PubMed
35.
Zurück zum Zitat Schiff T, Mateo LR, Delgado E, Cummins D, Zhang YP, DeVizio W (2011) Clinical efficacy in reducing dentin hypersensitivity of a dentifrice containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride compared to a dentifrice containing 8% strontium acetate and 1040 ppm fluoride under consumer usage conditions before and after switch-over. J Clin Dent 22(4):128–138PubMed Schiff T, Mateo LR, Delgado E, Cummins D, Zhang YP, DeVizio W (2011) Clinical efficacy in reducing dentin hypersensitivity of a dentifrice containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride compared to a dentifrice containing 8% strontium acetate and 1040 ppm fluoride under consumer usage conditions before and after switch-over. J Clin Dent 22(4):128–138PubMed
36.
Zurück zum Zitat Seong J, Davies M, Macdonald EL, Claydon NC, West NX (2018) Randomized clinical trial to determine if changes in dentin tubule occlusion visualized by SEM of replica impressions correlate with pain scores. Am J Dent 31(4):189–194PubMed Seong J, Davies M, Macdonald EL, Claydon NC, West NX (2018) Randomized clinical trial to determine if changes in dentin tubule occlusion visualized by SEM of replica impressions correlate with pain scores. Am J Dent 31(4):189–194PubMed
38.
Zurück zum Zitat Docimo R, Perugia C, Bartolino M, Maturo P, Montesani L, Zhang YP, Devizio W, Mateo LR, Dibart S (2011) Comparative evaluation of the efficacy of three commercially available toothpastes on dentin hypersensitivity reduction: an eight-week clinical study. J Clin Dent 22(4):121–127PubMed Docimo R, Perugia C, Bartolino M, Maturo P, Montesani L, Zhang YP, Devizio W, Mateo LR, Dibart S (2011) Comparative evaluation of the efficacy of three commercially available toothpastes on dentin hypersensitivity reduction: an eight-week clinical study. J Clin Dent 22(4):121–127PubMed
39.
Zurück zum Zitat Parkison CR, Wilson RJ (2011) A comparative in vitro study investigating the occlusion and mineralization properties of commercial dentifrices in a four-day dentin disc model, in vitro. J Clin Dent 22:68–73 Parkison CR, Wilson RJ (2011) A comparative in vitro study investigating the occlusion and mineralization properties of commercial dentifrices in a four-day dentin disc model, in vitro. J Clin Dent 22:68–73
40.
Zurück zum Zitat Saeki K, Marshall GW, Gansky SA, Parkison CR, Marshall SJ (2016) Strontium effects on root dentin tubule occlusion and nanomechanical properties. Acad Dent Mater 32(2):240–251CrossRef Saeki K, Marshall GW, Gansky SA, Parkison CR, Marshall SJ (2016) Strontium effects on root dentin tubule occlusion and nanomechanical properties. Acad Dent Mater 32(2):240–251CrossRef
42.
Zurück zum Zitat Orhan K, Aksoy U, Can-Karabulut DC, Kalender A (2011) Low level laser therapy of dentin hypersensitivity: a short-term clinical trial. Laser Med Sci 26:591–598CrossRef Orhan K, Aksoy U, Can-Karabulut DC, Kalender A (2011) Low level laser therapy of dentin hypersensitivity: a short-term clinical trial. Laser Med Sci 26:591–598CrossRef
45.
Zurück zum Zitat Rocha MOC, Cruz AACF, Santos DO, Oliveira DWD, Flexa OD, Gonçalves PF (2020) Sensitivity and specificity of assessment scales of dentin hypersensitivity – an accuracy study. Braz oral res 34(1807):3107 Rocha MOC, Cruz AACF, Santos DO, Oliveira DWD, Flexa OD, Gonçalves PF (2020) Sensitivity and specificity of assessment scales of dentin hypersensitivity – an accuracy study. Braz oral res 34(1807):3107
Metadaten
Titel
Combination of two desensitizing protocols to control dentin hypersensitivity in non-carious lesions: a randomized, double-blind clinical trial
verfasst von
Antonia Patricia Oliveira Barros
Cristiane de Melo Alencar
Alexandra de Melo Pingarilho Carneiro
Danielle da Silva Pompeu
Gabriela Monteiro Barbosa
Jesuína Lamartine Nogueira Araújo
Cecy Martins Silva
Publikationsdatum
05.08.2021
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Oral Investigations / Ausgabe 2/2022
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-021-04104-2

Neu im Fachgebiet Zahnmedizin

Wirksame Patientenverfügung kann Zwangsbehandlung von Menschen mit psychischen Erkrankungen verbieten

Betreuer müssen auch die Patientenverfügung psychisch erkrankter Menschen berücksichtigen, wenn sie sich darin gegen eine Zwangsbehandlung aussprechen, betont der Bundesgerichtshof.

Tätigkeitsrahmen für Physician Assistants neu abgesteckt von Bundesärztekammer

Ihr Positionspapier zum Berufsbild des Physician Assistant hat die Bundesärztekammer überarbeitet. Darin hat sie sich Gedanken gemacht, welche Aufgaben in Praxen typischerweise von PA übernommen werden können.

Statine: Was der G-BA-Beschluss für Praxen bedeutet

Nach dem G-BA-Beschluss zur erweiterten Verordnungsfähigkeit von Lipidsenkern rechnet die DEGAM mit 200 bis 300 neuen Dauerpatienten pro Praxis. Im Interview erläutert Präsidiumsmitglied Erika Baum, wie Hausärztinnen und Hausärzte am besten vorgehen.

Erhöhte Suizidrate unter US-Ärztinnen

Während der Arztberuf Männer eher vor Suizid schützt, erhöht er das Risiko bei Frauen – zumindest in den USA: Die Suizidinzidenz unter Ärztinnen ist um die Hälfte höher als unter Frauen mit anderen Berufen. Männliche Ärzte töten sich dennoch wesentlich häufiger selbst als weibliche.

Update Zahnmedizin

Bestellen Sie unseren kostenlosen Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.