Skip to main content

14.12.2017 | Retinal Disorders | Ausgabe 2/2018 Open Access

Graefe's Archive for Clinical and Experimental Ophthalmology 2/2018

Combined in-depth, 3D, en face imaging of the optic disc, optic disc pits and optic disc pit maculopathy using swept-source megahertz OCT at 1050 nm

Graefe's Archive for Clinical and Experimental Ophthalmology > Ausgabe 2/2018
Josef Maertz, Jan Philip Kolb, Thomas Klein, Kathrin J. Mohler, Matthias Eibl, Wolfgang Wieser, Robert Huber, Siegfried Priglinger, Armin Wolf
Wichtige Hinweise

Electronic supplementary material

The online version of this article (https://​doi.​org/​10.​1007/​s00417-017-3857-9) contains supplementary material, which is available to authorized users.



To demonstrate papillary imaging of eyes with optic disc pits (ODP) or optic disc pit associated maculopathy (ODP-M) with ultrahigh-speed swept-source optical coherence tomography (SS-OCT) at 1.68 million A-scans/s. To generate 3D-renderings of the papillary area with 3D volume-reconstructions of the ODP and highly resolved en face images from a single densely-sampled megahertz-OCT (MHz-OCT) dataset for investigation of ODP-characteristics.


A 1.68 MHz-prototype SS-MHz-OCT system at 1050 nm based on a Fourier-domain mode-locked laser was employed to acquire high-definition, 3D datasets with a dense sampling of 1600 × 1600 A-scans over a 45° field of view. Six eyes with ODPs, and two further eyes with glaucomatous alteration or without ocular pathology are presented. 3D-rendering of the deep papillary structures, virtual 3D-reconstructions of the ODPs and depth resolved isotropic en face images were generated using semiautomatic segmentation.


3D-rendering and en face imaging of the optic disc, ODPs and ODP associated pathologies showed a broad spectrum regarding ODP characteristics. Between individuals the shape of the ODP and the appending pathologies varied considerably. MHz-OCT en face imaging generates distinct top-view images of ODPs and ODP-M. MHz-OCT generates high resolution images of retinal pathologies associated with ODP-M and allows visualizing ODPs with depths of up to 2.7 mm.


Different patterns of ODPs can be visualized in patients for the first time using 3D-reconstructions and co-registered high-definition en face images extracted from a single densely sampled 1050 nm megahertz-OCT (MHz-OCT) dataset. As the immediate vicinity to the SAS and the site of intrapapillary proliferation is located at the bottom of the ODP it is crucial to image the complete structure and the whole depth of ODPs. Especially in very deep pits, where non-swept-source OCT fails to reach the bottom, conventional swept-source devices and the MHz-OCT alike are feasible and beneficial methods to examine deep details of optic disc pathologies, while the MHz-OCT bears the advantage of an essentially swifter imaging process.

Unsere Produktempfehlungen

e.Med Interdisziplinär


Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf

Gräfes Archiv


ESM 3. ONH_Movie_Pat2_fin. Reconstructed 3D–animation using the MHz-OCT-dataset of the optic disc in a right eye of a 26-year-old woman (Pat. 2 in Table 1). EDI-OCT (Spectralis Heidelberg) failed to measure the depth of the ODP in this case, whereas it was still possible measuring the ODP using in-depth MHz-OCT. Also this classic congenital ODP shows an ODP-Volume cast exhibiting two depth-peaks [Volume: 0.9185 mm3 / depth: 1805 μm]. (AVI 2294 kb)
ESM 4. ONH_Movie_Pat5_fin. Reconstructed 3D–animation using the MHz-OCT-dataset of the right eye of a 35-year-old man (Pat. 5 in Table 1). The animation shows a deep optic disc with central ODP adjacent to the main vessel trunk, with an increased volume in the respective optic disc-cast [Volume: 0.7824 mm3 / depth: 657 μm] (AVI 4234 kb)
ESM 5. ONH_Movie_Pat6_fin. Reconstructed 3D–animation using the MHz-OCT-dataset of the optic disc in a left eye of a 62-year-old woman with dense synchisis and ODP (Pat. 6 in Table 1). The animated 3D–volume-cast shows an ODP exhibiting its maximum depth-peak alongside the temporal margin of the optic disc [Volume: 0.2451 mm3 / depth: 618 μm]. (AVI 4446 kb)
Über diesen Artikel

Weitere Artikel der Ausgabe 2/2018

Graefe's Archive for Clinical and Experimental Ophthalmology 2/2018 Zur Ausgabe

Neu im Fachgebiet Augenheilkunde

25.03.2020 | Leitthema | Ausgabe 4/2020

Rechtliche Aspekte der Qualitätssicherung

Beispiel der intravitrealen operativen Injektionstherapie