nach oben

Erschienen in:

13.12.2016 | Case Report - Functional

Combined thalamic and subthalamic deep brain stimulation for tremor-dominant Parkinson’s disease

verfasst von: Markus F. Oertel, W. Michael M. Schüpbach, Joseph-André Ghika, Lennart H. Stieglitz, Michael Fiechter, Alain Kaelin-Lang, Andreas Raabe, Claudio Pollo

Erschienen in: Acta Neurochirurgica | Ausgabe 2/2017

Einloggen, um Zugang zu erhalten

Abstract

Deep brain stimulation (DBS) in the thalamic ventral intermediate (Vim) or the subthalamic nucleus (STN) reportedly improves medication-refractory Parkinson’s disease (PD) tremor. However, little is known about the potential synergic effects of combined Vim and STN DBS. We describe a 79-year-old man with medication-refractory tremor-dominant PD. Bilateral Vim DBS electrode implantation produced insufficient improvement. Therefore, the patient underwent additional unilateral left-sided STN DBS. Whereas Vim or STN stimulation alone led to partial improvement, persisting tremor resolution occurred after simultaneous stimulation. The combination of both targets may have a synergic effect and is an alternative option in suitable cases.

Anheim M, Batir A, Fraix V, Silem M, Chabardès S, Seigneuret E, Krack P, Benabid AL, Pollak P (2008) Improvement in Parkinson disease by subthalamic nucleus stimulation based on electrode placement: effects of reimplantation. Arch Neurol 65:612–616PubMed

Blomstedt P, Fytagoridis A, Åström M, Linder J, Forsgren L, Hariz MI (2012) Unilateral caudal zona incerta deep brain stimulation for Parkinsonian tremor. Parkinsonism Relat Disord 18:1062–1066CrossRefPubMed

Blomstedt P, Lindvall P, Linder J, Olivecrona M, Forsgren L, Hariz MI (2012) Reoperation after failed deep brain stimulation for essential tremor. World Neurosurg 78:7554.e1–7554.e5CrossRef

Coenen VA, Allert N, Paus S, Kronenbürger M, Urbach H, Mädler B (2014) Modulation of the cerebello-thalamo-cortical network in thalamic deep brain stimulation for tremor: a diffusion tensor imaging study. Neurosurgery 75:657–670CrossRefPubMed

Ellis TM, Foote KD, Fernandez HH, Sudhyadhom A, Rodriguez RL, Zeilman P, Jacobson CE 4th, Okun MS (2008) Reoperation for suboptimal outcomes after deep brain stimulation surgery. Neurosurgery 63:754–761CrossRefPubMed

Fraix V, Pollak P, Moro E, Chabardes S, Xie J, Ardouin C, Benabid AL (2005) Subthalamic nucleus stimulation in tremor dominant parkinsonian patients with previous thalamic surgery. J Neurol Neurosurg Psychiatry 76:246–248CrossRefPubMedPubMedCentral

Gallay MN, Jeanmonod D, Liu J, Morel A (2008) Human pallidothalamic and cerebellothalamic tracts: anatomical basis for functional stereotactic neurosurgery. Brain Struct Funct 212:443–463CrossRefPubMedPubMedCentral

Granziera C, Pollo C, Russmann H, Staedler C, Ghika J, Villemure JG, Burkhard PR, Vingerhoets FJ (2008) Sub-acute delayed failure of subthalamic DBS in Parkinson’s disease: the role of micro-lesion effect. Parkinsonism Relat Disord 14:109–113CrossRefPubMed

Hamel W, Herzog J, Kopper F, Pinsker M, Weinert D, Müller D, Krack P, Deuschl G, Mehdorn HM (2007) Deep brain stimulation in the subthalamic area is more effective than nucleus ventralis intermedius stimulation for bilateral intention tremor. Acta Neurochir (Wien) 149:749–758CrossRef

10.

Hariz MI, Krack P, Alesch F, Augustinsson LE, Bosch A, Ekberg R, Johansson F, Johnels B, Meyerson BA, N’Guyen JP, Pinter M, Pollak P, von Raison F, Rehncrona S, Speelman JD, Sydow O, Benabid AL (2008) Multicentre European study of thalamic stimulation for parkinsonian tremor: a 6 years follow-up. J Neurol Neurosurg Psychiatry 79:694–699CrossRefPubMed

11.

Khan S, Gill SS, Mooney L, White P, Whone A, Brooks DJ, Pavese N (2012) Combined pedunculopontine-subthalamic stimulation in Parkinson disease. Neurology 78:1090–1095CrossRefPubMedPubMedCentral

12.

Khan S, Javed S, Mooney L, White P, Plaha P, Whone A, Gill SS (2012) Clinical outcomes from bilateral versus unilateral stimulation of the pedunculopontine nucleus with and without concomitant caudal zona incerta region stimulation in Parkinson’s disease. Br J Neurosurg 26:722–725CrossRefPubMed

13.

Khan S, Mooney L, Plaha P, Javed S, White P, Whone AL, Gill SS (2011) Outcomes from stimulation of the caudal zona incerta and pedunculopontine nucleus in patients with Parkinson’s disease. Br J Neurosurg 25:273–280CrossRefPubMed

14.

Kim HJ, Jeon BS, Paek SH, Lee JY, Kim HJ, Kim CK, Kim DG (2010) Bilateral subthalamic deep brain stimulation in Parkinson disease patients with severe tremor. Neurosurgery 67:626–632CrossRefPubMed

15.

Mazzone P, Brown P, Dilazzaro V, Stanzione P, Oliviero A, Peppe A, Santilli V, Insola A, Altibrandi M (2005) Bilateral implantation in globus pallidus internus and in subthalamic nucleus in Parkinson’s disease. Neuromodulation 8:1–6CrossRefPubMed

16.

Mazzone P, Stocchi F, Galati S, Insola A, Altibrandi MG, Modugno N, Tropepi D, Brusa L, Stefani A (2006) Bilateral implantation of centromedian-parafascicularis complex and GPi: a new combination of unconventional targets for deep brain stimulation in severe Parkinson disease. Neuromodulation 9:221–228CrossRefPubMed

17.

Peppe A, Gasbarra A, Stefani A, Chiavalon C, Pierantozzi M, Fermi E, Stanzione P, Caltagirone C, Mazzone P (2008) Deep brain stimulation of CM/PF of thalamus could be the new elective target for tremor in advanced Parkinson’s disease? Parkinsonism Relat Disord 14:501–504CrossRefPubMed

18.

Peppe A, Pierantozzi M, Bassi A, Altibrandi MG, Brusa L, Stefani A, Stanzione P, Mazzone P (2004) Stimulation of the subthalamic nucleus compared with the globus pallidus internus in patients with Parkinson disease. J Neurosurg 101:195–200CrossRefPubMed

19.

Peppe A, Pierantozzi M, Chiavalon C, Marchetti F, Caltagirone C, Musicco M, Stanzione P, Stefani A (2010) Deep brain stimulation of the pedunculopontine tegmentum and subthalamic nucleus: effects on gait in Parkinson’s disease. Gait Posture 32:512–518CrossRefPubMed

20.

Romanelli P, Brontë-Stewart H, Courtney T, Heit G (2003) Possible necessity for deep brain stimulation of both the ventralis intermedius and subthalamic nuclei to resolve Holmes tremor. Case report. J Neurosurg 99:566–571CrossRefPubMed

21.

Stefani A, Lozano AM, Peppe A, Stanzione P, Galati S, Tropepi D, Pierantozzi M, Brusa L, Scarnati E, Mazzone P (2007) Bilateral deep brain stimulation of the pedunculopontine and subthalamic nuclei in severe Parkinson’s disease. Brain 130:1596–1607CrossRefPubMed

22.

Stefani A, Peppe A, Pierantozzi M, Galati S, Moschella V, Stanzione P, Mazzone P (2009) Multi-target strategy for parkinsonian patients: the role of deep brain stimulation in the centromedian-parafascicularis complex. Brain Res Bull 78:113–118CrossRefPubMed

Titel: Combined thalamic and subthalamic deep brain stimulation for tremor-dominant Parkinson’s disease
verfasst von: Markus F. Oertel
W. Michael M. Schüpbach
Joseph-André Ghika
Lennart H. Stieglitz
Michael Fiechter
Alain Kaelin-Lang
Andreas Raabe
Claudio Pollo
Publikationsdatum: 13.12.2016
Verlag: Springer Vienna
Erschienen in: Acta Neurochirurgica / Ausgabe 2/2017
Print ISSN: 0001-6268
Elektronische ISSN: 0942-0940
DOI: https://doi.org/10.1007/s00701-016-3044-5

Leitlinien kompakt für die Neurologie

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Neurologie

25.04.2024 | Hypotonie | Nachrichten

Update Neurologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

Combined thalamic and subthalamic deep brain stimulation for tremor-dominant Parkinson’s disease

Abstract

Leitlinien kompakt für die Neurologie

Neu im Fachgebiet Neurologie

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

Demenzkranke durch Antipsychotika vielfach gefährdet

Parkinson-Therapie im Wandel – aktuelle Leitlinie im Fokus

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein

Update Neurologie

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 2/2017

eLearning resources to supplement postgraduate neurosurgery training

A unique case of concomitant intra and extracranial Hansen’s disease

Predictors of early in-hospital death after decompressive craniectomy in swollen middle cerebral artery infarction

Frontal skull osteoblastoma with aneurysmal bone cyst-like changes associated with trauma during pregnancy: a case report

Outcome and prognostic factors after delayed second subarachnoid haemorrhage

Venous air embolism in the sitting position in cranial neurosurgery: incidence and severity according to the used monitoring

Leitlinien kompakt für die Neurologie

Neu im Fachgebiet Neurologie

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

Demenzkranke durch Antipsychotika vielfach gefährdet

Parkinson-Therapie im Wandel – aktuelle Leitlinie im Fokus

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein

Update Neurologie