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Erschienen in: Indian Journal of Surgery 6/2010

01.12.2010 | Original Article

Comparative Evaluation of Adhesions to Intraperitoneally Placed Fixation Materials: A Laparoscopic Study in Rats

Adhesions to Fixation Materials

verfasst von: Bulent Gungor, Zafer Malazgirt, Koray Topgül, Ali Gök, Mehmet Bilgin, Savaş Yürüker

Erschienen in: Indian Journal of Surgery | Ausgabe 6/2010

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Abstract

After laparoscopic ventral hernia repair, the nature of the adhesions to fixation materials or to mesh had not been clarified. We examined adhesion formation specific to the fixation material in rats. We designed an experimental laparoscopy setup, and placed four intraperitoneal fixation materials on the peritoneum of rats without a mesh graft. Another group of researchers documented the incidence and intensity of postoperative adhesion formation. The adhesion scores for the nickel-titanium anchor were significantly greater than those for polylactic acid (p = 0.004), a titanium tacker (p < 0.0001), and fibrin glue (p < 0.0001). No adhesions occurred in the fibrin glue group. Fibrin glue is the preferred fixation material because it produced no postoperative adhesions. The nickel-titanium anchor produced heavy adhesions but may be applicable for recurrent hernia cases and in patients with thin abdominal walls.
Literatur
1.
Zurück zum Zitat Lanzafame RJ, Stadler I, Brondon P, Soltz BA, Devore DP (2005) Preliminary assessment of postoperative adhesion formation after laser assisted mesh fixation to the peritoneal surface. J Laparoendoscopic Adv Surg Tech A 15(2):105–111CrossRef Lanzafame RJ, Stadler I, Brondon P, Soltz BA, Devore DP (2005) Preliminary assessment of postoperative adhesion formation after laser assisted mesh fixation to the peritoneal surface. J Laparoendoscopic Adv Surg Tech A 15(2):105–111CrossRef
2.
Zurück zum Zitat Joels CS, Matthews BD, Kercher KW, Austin C, Norton HJ, Williams TC, Heniford BT (2005) Evaluation of adhesion formation, mesh fixation strength and hydroxyproline content after intraabdominal placement of polytetrafluoroethylene mesh secured using titanium spiral tacks, nitinol anchors, and polypropylene suture or polyglactin 910 suture. Surg Endosc 19(6):780–785PubMedCrossRef Joels CS, Matthews BD, Kercher KW, Austin C, Norton HJ, Williams TC, Heniford BT (2005) Evaluation of adhesion formation, mesh fixation strength and hydroxyproline content after intraabdominal placement of polytetrafluoroethylene mesh secured using titanium spiral tacks, nitinol anchors, and polypropylene suture or polyglactin 910 suture. Surg Endosc 19(6):780–785PubMedCrossRef
3.
Zurück zum Zitat Novitsky YW, Harrell AG, Cristiano JA, Paton BL, Norton HJ, Peindl RD, Kercher KW, Heniford BT (2007) Comparative evaluation of adhesion formation, strength of ingrowth, and textile properties of prosthetic meshes after long term intraabdominal implantation in a rabbit. J Surg Res 140:6–11PubMedCrossRef Novitsky YW, Harrell AG, Cristiano JA, Paton BL, Norton HJ, Peindl RD, Kercher KW, Heniford BT (2007) Comparative evaluation of adhesion formation, strength of ingrowth, and textile properties of prosthetic meshes after long term intraabdominal implantation in a rabbit. J Surg Res 140:6–11PubMedCrossRef
4.
Zurück zum Zitat Kayaoğlu HA, Özkan N, Hazinedaroğlu SM, Ersoy ÖF, Erkek AB, Köseoğlu RD (2005) Comparison of adhesive properties of five different prosthetic materials used in hernioplasty. J Invest Surg 18(2):89–95PubMedCrossRef Kayaoğlu HA, Özkan N, Hazinedaroğlu SM, Ersoy ÖF, Erkek AB, Köseoğlu RD (2005) Comparison of adhesive properties of five different prosthetic materials used in hernioplasty. J Invest Surg 18(2):89–95PubMedCrossRef
5.
Zurück zum Zitat Conze J, Junge K, Klinge U, Weiss C, Polivoda M, Oettinger AP, Schumpelick V (2005) Intraabdominal adhesion formation of polypropylene mesh, influence of coverage of omentum and polyglactin. Surg Endosc 19(6):798–803PubMedCrossRef Conze J, Junge K, Klinge U, Weiss C, Polivoda M, Oettinger AP, Schumpelick V (2005) Intraabdominal adhesion formation of polypropylene mesh, influence of coverage of omentum and polyglactin. Surg Endosc 19(6):798–803PubMedCrossRef
6.
Zurück zum Zitat Eller R, Twaddell C, Poulos E, Jenevein E, McIntire D, Russell S (1994) Abdominal adhesions in laparoscopic hernia repair- an experimental study. Surg Endosc 8:181–184PubMedCrossRef Eller R, Twaddell C, Poulos E, Jenevein E, McIntire D, Russell S (1994) Abdominal adhesions in laparoscopic hernia repair- an experimental study. Surg Endosc 8:181–184PubMedCrossRef
7.
Zurück zum Zitat Mc Ginty JJ, Hogle NJ, Mc Carthy H, Fowler DL (2005) A comparative study of adhesion formation and abdominal wall ingrowth after laparoscopic ventral hernia repair in a porcine model using multiple types of mesh. Surg Endosc 19:786–790CrossRef Mc Ginty JJ, Hogle NJ, Mc Carthy H, Fowler DL (2005) A comparative study of adhesion formation and abdominal wall ingrowth after laparoscopic ventral hernia repair in a porcine model using multiple types of mesh. Surg Endosc 19:786–790CrossRef
8.
Zurück zum Zitat Malazgirt Z, Ulusoy AN, Gok Y, Karagoz F, Tac K (2000) Bioabsorbable membrane prevents adhesions to polypropylene mesh in rats. Hernia 4:129–133CrossRef Malazgirt Z, Ulusoy AN, Gok Y, Karagoz F, Tac K (2000) Bioabsorbable membrane prevents adhesions to polypropylene mesh in rats. Hernia 4:129–133CrossRef
9.
Zurück zum Zitat Le Blanc KA, Stout RW, Kearney MT, Paulson DB (2003) Comparison of adhesion formation associated with Pro-Tack (US Surgical) vs a new mesh fixation device, Salute (ONUX Medical). Surg Endosc 17:1409–1417CrossRef Le Blanc KA, Stout RW, Kearney MT, Paulson DB (2003) Comparison of adhesion formation associated with Pro-Tack (US Surgical) vs a new mesh fixation device, Salute (ONUX Medical). Surg Endosc 17:1409–1417CrossRef
10.
Zurück zum Zitat Borrazzo EC, Belmont MF, Boffa D, Fowler DI (2004) Effect of prosthetic material on adhesion formation after laparoscopic ventral hernia repair in a porcine model. Hernia 8:108–112PubMedCrossRef Borrazzo EC, Belmont MF, Boffa D, Fowler DI (2004) Effect of prosthetic material on adhesion formation after laparoscopic ventral hernia repair in a porcine model. Hernia 8:108–112PubMedCrossRef
11.
Zurück zum Zitat Karahasanoğlu T, Onur E, Baca B, Hamzaoğlu I, Pekmezci S, Boler DE, Kılıç N, Altuğ N (2004) Spiral tacks may contribute to intraabdominal adhesion formation. Surg Today 34:860–864PubMed Karahasanoğlu T, Onur E, Baca B, Hamzaoğlu I, Pekmezci S, Boler DE, Kılıç N, Altuğ N (2004) Spiral tacks may contribute to intraabdominal adhesion formation. Surg Today 34:860–864PubMed
12.
Zurück zum Zitat Winslow ER, Diaz S, Desai K, Meininger T, Soper NJ, Klingensmith ME (2004) Laparoscopic incisional hernia repair in a porcine model: what do transfixion sutures add? Surg Endosc 18(3):529–535PubMedCrossRef Winslow ER, Diaz S, Desai K, Meininger T, Soper NJ, Klingensmith ME (2004) Laparoscopic incisional hernia repair in a porcine model: what do transfixion sutures add? Surg Endosc 18(3):529–535PubMedCrossRef
13.
Zurück zum Zitat Mazuji MK, Fadhli HA (1965) Peritoneal adhesions; prevention with povidone and dextran 75. Arch Surg 91(6):872–874PubMedCrossRef Mazuji MK, Fadhli HA (1965) Peritoneal adhesions; prevention with povidone and dextran 75. Arch Surg 91(6):872–874PubMedCrossRef
14.
Zurück zum Zitat Avital S, Bollinger TJ, Wilkinson JD, Marchetti F, Hellinger MD, Sands LR (2005) Preventing intraabdominal adhesions with polylactic acid film: an animal study. Dis Colon Rectum 48(1):153–157PubMedCrossRef Avital S, Bollinger TJ, Wilkinson JD, Marchetti F, Hellinger MD, Sands LR (2005) Preventing intraabdominal adhesions with polylactic acid film: an animal study. Dis Colon Rectum 48(1):153–157PubMedCrossRef
15.
Zurück zum Zitat Attwood SEA, Caldwell MTP, Marks P, McDermott M, Stephens RB (1994) Adhesions after laparoscopic inguinal hernia repair. A comparison of extra versus intra peritoneal placement of a polypropylene mesh in an animal model. Surg Endosc 8:777–780PubMedCrossRef Attwood SEA, Caldwell MTP, Marks P, McDermott M, Stephens RB (1994) Adhesions after laparoscopic inguinal hernia repair. A comparison of extra versus intra peritoneal placement of a polypropylene mesh in an animal model. Surg Endosc 8:777–780PubMedCrossRef
16.
Zurück zum Zitat Zong X, Li S, Chen E, Garlick B, Kim KS, Fang D, Chiu J, Zimmerman T, Brathwaite C, Hsiao BS, Chu B (2004) Prevention of postsurgery-induced abdominal adhesions by electrospun bioabsorbable nanofibrous poly(lactide-co-glycolide)-based membranes. Ann Surg 240(5):910–915PubMedCrossRef Zong X, Li S, Chen E, Garlick B, Kim KS, Fang D, Chiu J, Zimmerman T, Brathwaite C, Hsiao BS, Chu B (2004) Prevention of postsurgery-induced abdominal adhesions by electrospun bioabsorbable nanofibrous poly(lactide-co-glycolide)-based membranes. Ann Surg 240(5):910–915PubMedCrossRef
17.
Zurück zum Zitat Baykal A, Onat D, Raşa K, Renda N, Sayek I (1997) Effects of polyglycolic acid and polypropylene meshes on postoperative adhesion formation in mice. World J Surg 21:579–583PubMedCrossRef Baykal A, Onat D, Raşa K, Renda N, Sayek I (1997) Effects of polyglycolic acid and polypropylene meshes on postoperative adhesion formation in mice. World J Surg 21:579–583PubMedCrossRef
18.
Zurück zum Zitat Duffy AJ, Hogle NJ, LaPerle KM, Fowler DI (2004) Comparison of two composite meshes using two fixation devices in a porcine laparoscopic ventral hernia repair model. Hernia 8:358–364PubMedCrossRef Duffy AJ, Hogle NJ, LaPerle KM, Fowler DI (2004) Comparison of two composite meshes using two fixation devices in a porcine laparoscopic ventral hernia repair model. Hernia 8:358–364PubMedCrossRef
19.
Zurück zum Zitat Saed GM, Kruger M, Diamond MP (2004) Expression of transforming growt factor –beta and extracellular matrix by human peritoneal mesothelial cells and by fibroblasts from normal peritoneum and adhesions: effect of Tisseel. Wound Repair Regen 12(5):557–564PubMedCrossRef Saed GM, Kruger M, Diamond MP (2004) Expression of transforming growt factor –beta and extracellular matrix by human peritoneal mesothelial cells and by fibroblasts from normal peritoneum and adhesions: effect of Tisseel. Wound Repair Regen 12(5):557–564PubMedCrossRef
20.
Zurück zum Zitat Katkhouda N (2004) A new technique for laparoscopic hernia repair using fibrin sealant. Surg Technol Int 12:120–126PubMed Katkhouda N (2004) A new technique for laparoscopic hernia repair using fibrin sealant. Surg Technol Int 12:120–126PubMed
21.
Zurück zum Zitat Schulze S, Kristiansen VB, Hansen BF, Rosenberg J (2005) Biological tissue adhesive for mesh application in pigs. Surg Endosc 19:342–344PubMedCrossRef Schulze S, Kristiansen VB, Hansen BF, Rosenberg J (2005) Biological tissue adhesive for mesh application in pigs. Surg Endosc 19:342–344PubMedCrossRef
22.
Zurück zum Zitat Gonzales R, Rodeheaver GT, Moody DL, Foresman PA, Ramshaw BJ (2004) Resistance to adhesion formation: a comparative study of treated and untreated mesh products placed in the abdominal cavity. Hernia 8:213–219 Gonzales R, Rodeheaver GT, Moody DL, Foresman PA, Ramshaw BJ (2004) Resistance to adhesion formation: a comparative study of treated and untreated mesh products placed in the abdominal cavity. Hernia 8:213–219
Metadaten
Titel
Comparative Evaluation of Adhesions to Intraperitoneally Placed Fixation Materials: A Laparoscopic Study in Rats
Adhesions to Fixation Materials
verfasst von
Bulent Gungor
Zafer Malazgirt
Koray Topgül
Ali Gök
Mehmet Bilgin
Savaş Yürüker
Publikationsdatum
01.12.2010
Verlag
Springer-Verlag
Erschienen in
Indian Journal of Surgery / Ausgabe 6/2010
Print ISSN: 0972-2068
Elektronische ISSN: 0973-9793
DOI
https://doi.org/10.1007/s12262-010-0168-3

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