Skip to main content
main-content

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Chinese Medicine 1/2018

Comparative study of the polyphenol content-related anti-inflammatory and antioxidant activities of two Urera aurantiaca specimens from different geographical areas

Zeitschrift:
Chinese Medicine > Ausgabe 1/2018
Autoren:
Carla Marrassini, Ignacio Peralta, Claudia Anesini
Wichtige Hinweise

Electronic supplementary material

The online version of this article (https://​doi.​org/​10.​1186/​s13020-018-0181-1) contains supplementary material, which is available to authorized users.

Abstract

Background

Urera aurantiaca is an Argentinean species that has been traditionally used to treat symptoms of inflammation. The aim of this study was to determine and compare the anti-inflammatory and antioxidant effects of two specimens of Urera aurantiaca obtained in the provinces of Salta and Misiones, which are two different geographical areas of Argentina.

Methods

The anti-inflammatory activity of the extracts was tested in LPS-stimulated macrophages through the DPPH radical scavenging activity, the SOD-like activity, the reducing power and the inhibition of lipid peroxidation. The anti-inflammatory activity was also evaluated by the inhibition of albumin denaturation and proteinase inhibitory action tests. The total polyphenols, flavonoids and tannins content were quantified.

Results

Both extracts were able to reduce the augmented NO release in LPS-activated macrophages and showed antioxidant and in vitro anti-inflammatory activities. The polyphenols content was higher in the extract obtained from the specimen from Salta than in that obtained in Misiones. This finding accounts for the higher anti-inflammatory and antioxidant properties obtained with the former.

Conclusion

The differences in chemical composition and the biological activities observed between the extracts are probably related to the different environmental conditions found in both provinces.
Zusatzmaterial
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 1/2018

Chinese Medicine 1/2018 Zur Ausgabe