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Erschienen in: Archives of Osteoporosis 1/2017

01.12.2017 | Original Article

Comparing self-perceived and estimated fracture risk by FRAX® of women with osteoporosis

verfasst von: Petra Baji, László Gulácsi, Csaba Horváth, Valentin Brodszky, Fanni Rencz, Márta Péntek

Erschienen in: Archives of Osteoporosis | Ausgabe 1/2017

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Abstract

Summary

In this study, we compared subjective fracture risks of Hungarian women with osteoporosis to FRAX®-based estimates. Patients with a previous fracture, parental hip fracture, low femoral T-score, higher age, and higher BMI were more likely to underestimate their risks. Patients also failed to associate risk factors with an increased risk of fractures.

Purpose

The main objectives were to explore associations between self-perceived 10-year fracture risks of women with osteoporosis (OP) and their risks calculated by the FRAX® algorithm and to identify determinants of the underestimation of risk.

Methods

We carried out a cross-sectional study in 11 OP centers in Hungary and collected data on the risk factors considered by the FRAX® calculator. Patients estimated their subjective 10-year probability of any major osteoporotic and hip fracture numerically, in percentages and also on a visual analog scale (VAS). We compared subjective and FRAX® estimates and applied logistic regression to analyze the determinants of the underestimation of risk. Associations between risk factors and subjective risk were explored using linear probability models.

Results

Nine hundred seventy-two OP patients were included in the analysis. Major OP and hip fracture risk by FRAX® were on average 20.1 and 10.5%, while subjective estimates were significantly higher, 30.0 and 24.7%, respectively. Correlations between FRAX® and subjective measures were very weak (r = 0.12–0.16). Underestimation of major OP fracture risk was associated with having had a single previous fracture (OR = 2.0), parental hip fracture (OR = 3.4), femoral T-score ≤−2.5 (OR = 4.2), higher age, body mass index, and better general health state. We did not find significant associations between subjective risk estimates and most of the risk factors except for previous fractures.

Conclusions

Hungarian OP patients fail to recognize most of the risk factors of fractures. Thus, education of patients about these risk factors would be beneficial especially for the elderly with a low femoral T-score and parental hip fracture history.
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Literatur
1.
Zurück zum Zitat Klibanski A, Adams-Campbell L, Bassford TL, Blair SN, Boden SD, Dickersin K, Gifford DR, Glasse L, Goldring SR, Hruska K (2001) Osteoporosis prevention, diagnosis, and therapy. J Am Med Assoc 285(6):785–795CrossRef Klibanski A, Adams-Campbell L, Bassford TL, Blair SN, Boden SD, Dickersin K, Gifford DR, Glasse L, Goldring SR, Hruska K (2001) Osteoporosis prevention, diagnosis, and therapy. J Am Med Assoc 285(6):785–795CrossRef
2.
Zurück zum Zitat Lorentzon M, Cummings S (2015) Osteoporosis: the evolution of a diagnosis. J Intern Med 277(6):650–661CrossRefPubMed Lorentzon M, Cummings S (2015) Osteoporosis: the evolution of a diagnosis. J Intern Med 277(6):650–661CrossRefPubMed
3.
Zurück zum Zitat Lips P, van Schoor NM (2005) Quality of life in patients with osteoporosis. Osteoporos Int 16(5):447–455CrossRefPubMed Lips P, van Schoor NM (2005) Quality of life in patients with osteoporosis. Osteoporos Int 16(5):447–455CrossRefPubMed
4.
Zurück zum Zitat Moja L, Piatti A, Pecoraro V, Ricci C, Virgili G, Salanti G, Germagnoli L, Liberati A, Banfi G (2012) Timing matters in hip fracture surgery: patients operated within 48 hours have better outcomes. A meta-analysis and meta-regression of over 190,000 patients. PLoS One 7(10):e46175CrossRefPubMedPubMedCentral Moja L, Piatti A, Pecoraro V, Ricci C, Virgili G, Salanti G, Germagnoli L, Liberati A, Banfi G (2012) Timing matters in hip fracture surgery: patients operated within 48 hours have better outcomes. A meta-analysis and meta-regression of over 190,000 patients. PLoS One 7(10):e46175CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat Nazrun AS, Tzar MN, Mokhtar SA, Mohamed IN (2014) A systematic review of the outcomes of osteoporotic fracture patients after hospital discharge: morbidity, subsequent fractures, and mortality. Ther Clin Risk Manag 10:937PubMedPubMedCentral Nazrun AS, Tzar MN, Mokhtar SA, Mohamed IN (2014) A systematic review of the outcomes of osteoporotic fracture patients after hospital discharge: morbidity, subsequent fractures, and mortality. Ther Clin Risk Manag 10:937PubMedPubMedCentral
6.
Zurück zum Zitat Grover ML, Edwards FD, Chang Y-HH, Cook CB, Behrens MC, Dueck AC (2014) Fracture risk perception study: patient self-perceptions of bone health often disagree with calculated fracture risk. Womens Health Issues 24(1):e69–e75CrossRefPubMed Grover ML, Edwards FD, Chang Y-HH, Cook CB, Behrens MC, Dueck AC (2014) Fracture risk perception study: patient self-perceptions of bone health often disagree with calculated fracture risk. Womens Health Issues 24(1):e69–e75CrossRefPubMed
7.
Zurück zum Zitat Rothmann M, Ammentorp J, Bech M, Gram J, Rasmussen O, Barkmann R, Glüer C, Hermann A (2015) Self-perceived facture risk: factors underlying women’s perception of risk for osteoporotic fractures: the Risk-Stratified Osteoporosis Strategy Evaluation study (ROSE). Osteoporos Int 26(2):689–697CrossRefPubMed Rothmann M, Ammentorp J, Bech M, Gram J, Rasmussen O, Barkmann R, Glüer C, Hermann A (2015) Self-perceived facture risk: factors underlying women’s perception of risk for osteoporotic fractures: the Risk-Stratified Osteoporosis Strategy Evaluation study (ROSE). Osteoporos Int 26(2):689–697CrossRefPubMed
8.
Zurück zum Zitat Siris ES, Gehlbach S, Adachi J, Boonen S, Chapurlat R, Compston J, Cooper C, Delmas P, Diez-Perez A, Hooven FH (2011) Failure to perceive increased risk of fracture in women 55 years and older: the Global Longitudinal Study of Osteoporosis in Women (GLOW). Osteoporos Int 22(1):27–35CrossRefPubMed Siris ES, Gehlbach S, Adachi J, Boonen S, Chapurlat R, Compston J, Cooper C, Delmas P, Diez-Perez A, Hooven FH (2011) Failure to perceive increased risk of fracture in women 55 years and older: the Global Longitudinal Study of Osteoporosis in Women (GLOW). Osteoporos Int 22(1):27–35CrossRefPubMed
9.
Zurück zum Zitat Becker MH, Drachman RH, Kirscht JP (1974) A new approach to explaining sick-role behavior in low-income populations. Am J Public Health 64(3):205–216CrossRefPubMedPubMedCentral Becker MH, Drachman RH, Kirscht JP (1974) A new approach to explaining sick-role behavior in low-income populations. Am J Public Health 64(3):205–216CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Janz NK, Becker MH (1984) The health belief model: a decade later. Health Educ Behav 11(1):1–47 Janz NK, Becker MH (1984) The health belief model: a decade later. Health Educ Behav 11(1):1–47
11.
Zurück zum Zitat Rosenstock IM (2005) Why people use health services. Milbank Quarterly 83 (4): Online-only-Online-only Rosenstock IM (2005) Why people use health services. Milbank Quarterly 83 (4): Online-only-Online-only
12.
Zurück zum Zitat Weinstein ND (1993) Testing four competing theories of health-protective behavior. Health Psychol 12(4):324CrossRefPubMed Weinstein ND (1993) Testing four competing theories of health-protective behavior. Health Psychol 12(4):324CrossRefPubMed
13.
Zurück zum Zitat Brewer NT, Chapman GB, Gibbons FX, Gerrard M, McCaul KD, Weinstein ND (2007) Meta-analysis of the relationship between risk perception and health behavior: the example of vaccination. Health Psychol 26(2):136CrossRefPubMed Brewer NT, Chapman GB, Gibbons FX, Gerrard M, McCaul KD, Weinstein ND (2007) Meta-analysis of the relationship between risk perception and health behavior: the example of vaccination. Health Psychol 26(2):136CrossRefPubMed
14.
Zurück zum Zitat Floyd DL, Prentice-Dunn S, Rogers RW (2000) A meta-analysis of research on protection motivation theory. J Appl Soc Psychol 30(2):407–429CrossRef Floyd DL, Prentice-Dunn S, Rogers RW (2000) A meta-analysis of research on protection motivation theory. J Appl Soc Psychol 30(2):407–429CrossRef
15.
Zurück zum Zitat Poulos C, Yang J-C, Levin C, Van Minh H, Giang KB, Nguyen D (2011) Mothers’ preferences and willingness to pay for HPV vaccines in Vinh Long Province, Vietnam. Soc Sci Med 73(2):226–234CrossRefPubMed Poulos C, Yang J-C, Levin C, Van Minh H, Giang KB, Nguyen D (2011) Mothers’ preferences and willingness to pay for HPV vaccines in Vinh Long Province, Vietnam. Soc Sci Med 73(2):226–234CrossRefPubMed
16.
Zurück zum Zitat Schousboe JT (2013) Adherence with medications used to treat osteoporosis: behavioral insights. Current Osteoporos Rep 11(1):21–29CrossRef Schousboe JT (2013) Adherence with medications used to treat osteoporosis: behavioral insights. Current Osteoporos Rep 11(1):21–29CrossRef
17.
Zurück zum Zitat Lakatos P, Takács I, Marton I, Tóth E, Zoltan C, Lang Z, Psachoulia E, Intorcia M (2016) A retrospective longitudinal database study of persistence and compliance with treatment of osteoporosis in Hungary. Calcif Tissue Int 98(3):215–225CrossRefPubMed Lakatos P, Takács I, Marton I, Tóth E, Zoltan C, Lang Z, Psachoulia E, Intorcia M (2016) A retrospective longitudinal database study of persistence and compliance with treatment of osteoporosis in Hungary. Calcif Tissue Int 98(3):215–225CrossRefPubMed
19.
Zurück zum Zitat Boncz I, Sebestyén A (2006) Financial deficits in the health services of the UK and Hungary. Lancet 368(9539):917–918CrossRefPubMed Boncz I, Sebestyén A (2006) Financial deficits in the health services of the UK and Hungary. Lancet 368(9539):917–918CrossRefPubMed
21.
Zurück zum Zitat Jones SM, Gell NM, Roth JA, Scholes D, LaCroix AZ (2015) The relationship of perceived risk and biases in perceived risk to fracture prevention behavior in older women. Ann Behav Med 49(5):696–703CrossRefPubMedPubMedCentral Jones SM, Gell NM, Roth JA, Scholes D, LaCroix AZ (2015) The relationship of perceived risk and biases in perceived risk to fracture prevention behavior in older women. Ann Behav Med 49(5):696–703CrossRefPubMedPubMedCentral
22.
Zurück zum Zitat Marques A, Ferreira RJ, Santos E, Loza E, Carmona L, da Silva JAP (2015) The accuracy of osteoporotic fracture risk prediction tools: a systematic review and meta-analysis. Ann Rheum Dis 74(11):1958–1967CrossRefPubMed Marques A, Ferreira RJ, Santos E, Loza E, Carmona L, da Silva JAP (2015) The accuracy of osteoporotic fracture risk prediction tools: a systematic review and meta-analysis. Ann Rheum Dis 74(11):1958–1967CrossRefPubMed
23.
Zurück zum Zitat Nayak S, Edwards D, Saleh A, Greenspan S (2014) Performance of risk assessment instruments for predicting osteoporotic fracture risk: a systematic review. Osteoporos Int 25(1):23–49CrossRefPubMed Nayak S, Edwards D, Saleh A, Greenspan S (2014) Performance of risk assessment instruments for predicting osteoporotic fracture risk: a systematic review. Osteoporos Int 25(1):23–49CrossRefPubMed
24.
Zurück zum Zitat Kanis J, McCloskey E, Johansson H, Strom O, Borgstrom F, Odén A (2008) Case finding for the management of osteoporosis with FRAX®—assessment and intervention thresholds for the UK. Osteoporos Int 19(10):1395–1408CrossRefPubMed Kanis J, McCloskey E, Johansson H, Strom O, Borgstrom F, Odén A (2008) Case finding for the management of osteoporosis with FRAX®—assessment and intervention thresholds for the UK. Osteoporos Int 19(10):1395–1408CrossRefPubMed
25.
26.
27.
Zurück zum Zitat Langer FW, da Silveira Codevilla AA, Bringhenti R, Dal Osto LC, Campos TR, Martins TT, Barin AE, Rigo PH, Boufleuer ND, Santinon SF, Kipper K, Rodrigues J, Premaor MO (2016) Low self-awareness of osteoporosis and fracture risk among postmenopausal women. Arch Osteoporos 11(1):27. doi:10.1007/s11657-016-0266-3 CrossRefPubMed Langer FW, da Silveira Codevilla AA, Bringhenti R, Dal Osto LC, Campos TR, Martins TT, Barin AE, Rigo PH, Boufleuer ND, Santinon SF, Kipper K, Rodrigues J, Premaor MO (2016) Low self-awareness of osteoporosis and fracture risk among postmenopausal women. Arch Osteoporos 11(1):27. doi:10.​1007/​s11657-016-0266-3 CrossRefPubMed
28.
Zurück zum Zitat Péntek M, Gulácsi L, Tóth E, Baji P, Brodszky V, Horváth C (2016) Ten-year fracture risk by FRAX(®) of women with osteoporosis attending osteoporosis care in Hungary. Orv Hetil 157(4):146–153CrossRefPubMed Péntek M, Gulácsi L, Tóth E, Baji P, Brodszky V, Horváth C (2016) Ten-year fracture risk by FRAX(®) of women with osteoporosis attending osteoporosis care in Hungary. Orv Hetil 157(4):146–153CrossRefPubMed
29.
Zurück zum Zitat Cosman F, De Beur S, LeBoff M, Lewiecki E, Tanner B, Randall S, Lindsay R (2014) Clinician’s guide to prevention and treatment of osteoporosis. Osteoporos Int 25(10):2359–2381CrossRefPubMedPubMedCentral Cosman F, De Beur S, LeBoff M, Lewiecki E, Tanner B, Randall S, Lindsay R (2014) Clinician’s guide to prevention and treatment of osteoporosis. Osteoporos Int 25(10):2359–2381CrossRefPubMedPubMedCentral
31.
Zurück zum Zitat de Bruin WB, Carman KG (2012) Measuring risk perceptions what does the excessive use of 50% mean? Med Decis Mak 32(2):232–236CrossRef de Bruin WB, Carman KG (2012) Measuring risk perceptions what does the excessive use of 50% mean? Med Decis Mak 32(2):232–236CrossRef
32.
Zurück zum Zitat Eibner F, Barth J, Helmes A, Bengel J (2006) Variations in subjective breast cancer risk estimations when using different measurements for assessing breast cancer risk perception. Health Risk Soc 8(2):197–210CrossRef Eibner F, Barth J, Helmes A, Bengel J (2006) Variations in subjective breast cancer risk estimations when using different measurements for assessing breast cancer risk perception. Health Risk Soc 8(2):197–210CrossRef
33.
Zurück zum Zitat Haase N, Renkewitz F, Betsch C (2013) The measurement of subjective probability: evaluating the sensitivity and accuracy of various scales. Risk Anal 33(10):1812–1828PubMed Haase N, Renkewitz F, Betsch C (2013) The measurement of subjective probability: evaluating the sensitivity and accuracy of various scales. Risk Anal 33(10):1812–1828PubMed
Metadaten
Titel
Comparing self-perceived and estimated fracture risk by FRAX® of women with osteoporosis
verfasst von
Petra Baji
László Gulácsi
Csaba Horváth
Valentin Brodszky
Fanni Rencz
Márta Péntek
Publikationsdatum
01.12.2017
Verlag
Springer London
Erschienen in
Archives of Osteoporosis / Ausgabe 1/2017
Print ISSN: 1862-3522
Elektronische ISSN: 1862-3514
DOI
https://doi.org/10.1007/s11657-016-0300-5

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