Skip to main content
Erschienen in: Clinical Oral Investigations 8/2019

28.11.2018 | Original Article

Comparing the effects of three different fluoride-releasing agents on white spot lesion prevention in patients treated with full coverage rapid maxillary expanders

verfasst von: Yasemin Nur Korkmaz, Ahmet Yagci

Erschienen in: Clinical Oral Investigations | Ausgabe 8/2019

Einloggen, um Zugang zu erhalten

Abstract

Objective

The aim of this study was to assess the effects of three different fluoride-releasing agents on preventing white spot lesions that occur during treatment with full coverage rapid maxillary expanders.

Materials and methods

A total of 48 patients with transverse maxillary deficiency were randomly assigned to four equal groups. A fluoride-containing agent was applied to teeth before cementation of the full coverage acrylic-bonded rapid maxillary expanders in the three experimental groups (gel, varnish, and sealent in groups 1, 2, and 3, respectively), while the control group received no agent application. Quantitative light-induced fluorescence (QLF) images of the patients were obtained before cementation and after decementation of the appliances. Four parameters (ΔF, ΔFmax, A, and ΔR) were evaluated on maxillary ten anterior teeth.

Results

In the fluoride gel group, upper central and lateral incisors, right first and left second premolars showed significant decreases in fluorescence levels indicating demineralization. Right central and left lateral incisors showed significant white spot lesion formation in the fluoride varnish group. Right and left central incisors and left first premolar were the teeth that mineral loss was observed in the sealent group, while all of the teeth except canines and first premolars showed significant demineralization in the control group.

Conclusions

Multifluorid varnish and Proseal sealant were effective on preventing demineralization and should be applied to teeth clinically before appliance cementation.

Clinical relevance

Demineralization is a major problem during orthodontic treatment. The application of effective fluoride-releasing agents could prevent this major iatrogenic complication.
Literatur
1.
Zurück zum Zitat Thylstrup A, Fejerskov O (1994) Clinical and pathological features of dental caries. In: Textbook of clinical cariology, 2nd edn. Handelshøjskolens Forlag, Copenhagen, pp 111–157 Thylstrup A, Fejerskov O (1994) Clinical and pathological features of dental caries. In: Textbook of clinical cariology, 2nd edn. Handelshøjskolens Forlag, Copenhagen, pp 111–157
2.
Zurück zum Zitat Ogaard B (1989) Prevalence of white spot lesions in 19-year-olds: a study on untreated and orthodontically treated persons 5 years after treatment. Am J Orthod Dentofac Orthop 96:423–427CrossRef Ogaard B (1989) Prevalence of white spot lesions in 19-year-olds: a study on untreated and orthodontically treated persons 5 years after treatment. Am J Orthod Dentofac Orthop 96:423–427CrossRef
3.
Zurück zum Zitat Chatterjee R, Kleinberg I (1979) Effect of orthodontic band placement on the chemical composition of human incisor tooth plaque. Arch Oral Biol 24:97–100CrossRefPubMed Chatterjee R, Kleinberg I (1979) Effect of orthodontic band placement on the chemical composition of human incisor tooth plaque. Arch Oral Biol 24:97–100CrossRefPubMed
4.
Zurück zum Zitat Bloom RH, Brown LR (1964) A study of the effects of orthodontic appliances on the oral microbial flora. Oral Surg Oral Med Oral Pathol 17:658–667CrossRefPubMed Bloom RH, Brown LR (1964) A study of the effects of orthodontic appliances on the oral microbial flora. Oral Surg Oral Med Oral Pathol 17:658–667CrossRefPubMed
5.
Zurück zum Zitat Yagci A, Korkmaz YN, Buyuk SK, Yagci F, Atilla AO (2016) White spot lesion formation after treatment with full-coverage rapid maxillary expanders. Am J Orthod Dentofac Orthop 149:331–338CrossRef Yagci A, Korkmaz YN, Buyuk SK, Yagci F, Atilla AO (2016) White spot lesion formation after treatment with full-coverage rapid maxillary expanders. Am J Orthod Dentofac Orthop 149:331–338CrossRef
6.
Zurück zum Zitat Cate JM (1999) Current concepts on the theories of the mechanism of action of fluoride. Acta Odontol Scand 57:325–329CrossRefPubMed Cate JM (1999) Current concepts on the theories of the mechanism of action of fluoride. Acta Odontol Scand 57:325–329CrossRefPubMed
7.
Zurück zum Zitat de Leeuw NH (2004) Resisting the onset of hydroxyapatite dissolution through the incorporation of fluoride. J Phys Chem Biophys 108:1809–1811CrossRef de Leeuw NH (2004) Resisting the onset of hydroxyapatite dissolution through the incorporation of fluoride. J Phys Chem Biophys 108:1809–1811CrossRef
8.
Zurück zum Zitat Øgaard B (1990) Effects of fluoride on caries development and progression in vivo. J Dent Res 69:813–819CrossRefPubMed Øgaard B (1990) Effects of fluoride on caries development and progression in vivo. J Dent Res 69:813–819CrossRefPubMed
9.
Zurück zum Zitat Ogaard B, Gjermo P, Rolla G (1980) Plaque-inhibiting effect in orthodontic patients of a dentifrice containing stannous fluoride. Am J Orthod 78:266–272CrossRefPubMed Ogaard B, Gjermo P, Rolla G (1980) Plaque-inhibiting effect in orthodontic patients of a dentifrice containing stannous fluoride. Am J Orthod 78:266–272CrossRefPubMed
10.
Zurück zum Zitat Dawes C, Jenkins G, Hardwick J, Leach S (1965) The relation between the fluoride concentrations in the dental plaque and in drinking water. Br Dent J 119:164–167PubMed Dawes C, Jenkins G, Hardwick J, Leach S (1965) The relation between the fluoride concentrations in the dental plaque and in drinking water. Br Dent J 119:164–167PubMed
11.
Zurück zum Zitat Zimring JF, Isaacson RJ (1965) Forces produced by rapid maxillary expansion: III. Forces present during retention. Angle Orthod 35:178–186PubMed Zimring JF, Isaacson RJ (1965) Forces produced by rapid maxillary expansion: III. Forces present during retention. Angle Orthod 35:178–186PubMed
12.
Zurück zum Zitat Enaia M, Bock N, Ruf S (2011) White-spot lesions during multibracket appliance treatment: a challenge for clinical excellence. Am J Orthod Dentofac Orthop 140:17–24CrossRef Enaia M, Bock N, Ruf S (2011) White-spot lesions during multibracket appliance treatment: a challenge for clinical excellence. Am J Orthod Dentofac Orthop 140:17–24CrossRef
13.
Zurück zum Zitat Yagci A, Korkmaz YN, Yagci F, Atilla AO, Buyuk SK (2016) Effect of 3 cements on white spot lesion formation after full-coverage rapid maxillary expander: a comparative in-vivo study. Am J Orthod Dentofac Orthop 150:1005–1013CrossRef Yagci A, Korkmaz YN, Yagci F, Atilla AO, Buyuk SK (2016) Effect of 3 cements on white spot lesion formation after full-coverage rapid maxillary expander: a comparative in-vivo study. Am J Orthod Dentofac Orthop 150:1005–1013CrossRef
14.
Zurück zum Zitat Susan A-K, Forsberg C-M, de Jong EJ, Angmar-Månsson B (1998) A longitudinal laser fluorescence study of white spot lesions in orthodontic patients. Am J Orthod Dentofacial Orthop 113:595–602CrossRef Susan A-K, Forsberg C-M, de Jong EJ, Angmar-Månsson B (1998) A longitudinal laser fluorescence study of white spot lesions in orthodontic patients. Am J Orthod Dentofacial Orthop 113:595–602CrossRef
15.
Zurück zum Zitat Van der Veen M, de Jong EdJ (2000) Application of quantitative light-induced fluorescence for assessing early caries lesions. In: Assessment of Oral Health, vol 17. Karger Publishers, Basel, pp 144–162 Van der Veen M, de Jong EdJ (2000) Application of quantitative light-induced fluorescence for assessing early caries lesions. In: Assessment of Oral Health, vol 17. Karger Publishers, Basel, pp 144–162
16.
Zurück zum Zitat Amaechi BT, Higham SM (2002) Quantitative light-induced fluorescence: a potential tool for general dental assessment. J Biomed Opt 7:7–14CrossRefPubMed Amaechi BT, Higham SM (2002) Quantitative light-induced fluorescence: a potential tool for general dental assessment. J Biomed Opt 7:7–14CrossRefPubMed
17.
Zurück zum Zitat Kim HE, Kim B-I (2015) An in vitro comparison of quantitative light-induced fluorescence-digital and spectrophotometer on monitoring artificial white spot lesions. Photodiagn Photodyn Ther 12:378–384CrossRef Kim HE, Kim B-I (2015) An in vitro comparison of quantitative light-induced fluorescence-digital and spectrophotometer on monitoring artificial white spot lesions. Photodiagn Photodyn Ther 12:378–384CrossRef
18.
Zurück zum Zitat Kang S-M, Jeong S-H, Kim H-E, Kim B-I (2017) Photodiagnosis of white spot lesions after orthodontic treatment with a quantitative light-induced fluorescence-digital system: a pilot study. Oral Health Prev Dent 15:483–488PubMed Kang S-M, Jeong S-H, Kim H-E, Kim B-I (2017) Photodiagnosis of white spot lesions after orthodontic treatment with a quantitative light-induced fluorescence-digital system: a pilot study. Oral Health Prev Dent 15:483–488PubMed
19.
Zurück zum Zitat Gorelick L, Geiger AM, Gwinnett AJ (1982) Incidence of white spot formation after bonding and banding. Am J Orthod 81:93–98CrossRefPubMed Gorelick L, Geiger AM, Gwinnett AJ (1982) Incidence of white spot formation after bonding and banding. Am J Orthod 81:93–98CrossRefPubMed
20.
Zurück zum Zitat O'reilly M, Featherstone J (1987) Demineralization and remineralization around orthodontic appliances: an in vivo study. Am J Orthod Dentofac Orthop 92:33–40CrossRef O'reilly M, Featherstone J (1987) Demineralization and remineralization around orthodontic appliances: an in vivo study. Am J Orthod Dentofac Orthop 92:33–40CrossRef
21.
Zurück zum Zitat Geiger AM, Gorelick L, Gwinnett AJ, Benson BJ (1992) Reducing white spot lesions in orthodontic populations with fluoride rinsing. Am J Orthod Dentofac Orthop 101:403–407CrossRef Geiger AM, Gorelick L, Gwinnett AJ, Benson BJ (1992) Reducing white spot lesions in orthodontic populations with fluoride rinsing. Am J Orthod Dentofac Orthop 101:403–407CrossRef
22.
Zurück zum Zitat Dimitriadis AG, Sassouni V, Draus FJ (1974) The effects of topical fluoride applications underneath loose orthodontic bands. Angle Orthod 44:94–99PubMed Dimitriadis AG, Sassouni V, Draus FJ (1974) The effects of topical fluoride applications underneath loose orthodontic bands. Angle Orthod 44:94–99PubMed
23.
Zurück zum Zitat Ten Cate J, Van Loveren C (1999) Fluoride mechanisms. Dent Clin N Am 43:713–742PubMed Ten Cate J, Van Loveren C (1999) Fluoride mechanisms. Dent Clin N Am 43:713–742PubMed
24.
Zurück zum Zitat Arends J, Schüthof J (1975) Fluoride content in human enamel after fluoride application and washing–an in vitro study. Caries Res 9:363–372CrossRefPubMed Arends J, Schüthof J (1975) Fluoride content in human enamel after fluoride application and washing–an in vitro study. Caries Res 9:363–372CrossRefPubMed
25.
Zurück zum Zitat Retief D, Sorvas P, Bradley E, Taylor R, Walker A (1980) In vitro fluoride uptake, distribution and retention by human enamel after 1-and 24-hour application of various topical fluoride agents. J Dent Res 59:573–582CrossRefPubMed Retief D, Sorvas P, Bradley E, Taylor R, Walker A (1980) In vitro fluoride uptake, distribution and retention by human enamel after 1-and 24-hour application of various topical fluoride agents. J Dent Res 59:573–582CrossRefPubMed
26.
Zurück zum Zitat Silin A, Satygo E, Sadal'skiĭ I (2013) Efficacy of the caries preventive agents in children during mixed dentition period. Stomatologiia 93:58–60 Silin A, Satygo E, Sadal'skiĭ I (2013) Efficacy of the caries preventive agents in children during mixed dentition period. Stomatologiia 93:58–60
27.
Zurück zum Zitat Farhadian N, Miresmaeili A, Eslami B, Mehrabi S (2008) Effect of fluoride varnish on enamel demineralization around brackets: an in-vivo study. Am J Orthod Dentofac Orthop 133:95–98CrossRef Farhadian N, Miresmaeili A, Eslami B, Mehrabi S (2008) Effect of fluoride varnish on enamel demineralization around brackets: an in-vivo study. Am J Orthod Dentofac Orthop 133:95–98CrossRef
28.
Zurück zum Zitat Twetman S, Hallgren A, Petersson L (1995) Effect of an antibacterial varnish on mutans streptococci in plaque from enamel adjacent to orthodontic appliances. Caries Res 29:188–191CrossRefPubMed Twetman S, Hallgren A, Petersson L (1995) Effect of an antibacterial varnish on mutans streptococci in plaque from enamel adjacent to orthodontic appliances. Caries Res 29:188–191CrossRefPubMed
29.
Zurück zum Zitat Ogaard B, Larsson E, Glans R, Henriksson T, Birkhed D (1996) Antimicrobial effect of a chlorhexidine-thymol varnish (Cervitec) in orthodontic patients. A prospective, randomized clinical trial. J Orofac Orthop 58:206–213CrossRef Ogaard B, Larsson E, Glans R, Henriksson T, Birkhed D (1996) Antimicrobial effect of a chlorhexidine-thymol varnish (Cervitec) in orthodontic patients. A prospective, randomized clinical trial. J Orofac Orthop 58:206–213CrossRef
30.
Zurück zum Zitat Schmit JL, Staley RN, Wefel JS, Kanellis M, Jakobsen JR, Keenan PJ (2002) Effect of fluoride varnish on demineralization adjacent to brackets bonded with RMGI cement. Am J Orthod Dentofac Orthop 122:125–134CrossRef Schmit JL, Staley RN, Wefel JS, Kanellis M, Jakobsen JR, Keenan PJ (2002) Effect of fluoride varnish on demineralization adjacent to brackets bonded with RMGI cement. Am J Orthod Dentofac Orthop 122:125–134CrossRef
31.
Zurück zum Zitat Joseph V, Rossouw P, Basson N (1994) Some “sealants” seal—a scanning electron microscopy (SEM) investigation. Am J Orthod Dentofac Orthop 105:362–368CrossRef Joseph V, Rossouw P, Basson N (1994) Some “sealants” seal—a scanning electron microscopy (SEM) investigation. Am J Orthod Dentofac Orthop 105:362–368CrossRef
32.
Zurück zum Zitat Frazier MC, Southard TE, Doster PM (1996) Prevention of enamel demineralization during orthodontic treatment: an in vitro study using pit and fissure sealants. Am J Orthod Dentofac Orthop 110:459–465CrossRef Frazier MC, Southard TE, Doster PM (1996) Prevention of enamel demineralization during orthodontic treatment: an in vitro study using pit and fissure sealants. Am J Orthod Dentofac Orthop 110:459–465CrossRef
33.
Zurück zum Zitat Clark TJ (2010) The efficacy of ProSeal™, SeLECT Defense™, OrthoCoat™, and Biscover LV™ resin sealants on the prevention of enamel demineralization and white spot lesion formation. Dissertation, University of Iowa Clark TJ (2010) The efficacy of ProSeal™, SeLECT Defense™, OrthoCoat™, and Biscover LV™ resin sealants on the prevention of enamel demineralization and white spot lesion formation. Dissertation, University of Iowa
34.
Zurück zum Zitat Melrose C, Appleton J, Lovius B (1996) A scanning electron microscopic study of early enamel caries formed in vivo beneath orthodontic bands. Br J Orthod 23:43–47CrossRefPubMed Melrose C, Appleton J, Lovius B (1996) A scanning electron microscopic study of early enamel caries formed in vivo beneath orthodontic bands. Br J Orthod 23:43–47CrossRefPubMed
35.
Zurück zum Zitat Buren JL, Staley RN, Wefel J, Qian F (2008) Inhibition of enamel demineralization by an enamel sealant, pro seal: an in-vitro study. Am J Orthod Dentofac Orthop 133:88–94CrossRef Buren JL, Staley RN, Wefel J, Qian F (2008) Inhibition of enamel demineralization by an enamel sealant, pro seal: an in-vitro study. Am J Orthod Dentofac Orthop 133:88–94CrossRef
36.
Zurück zum Zitat Hu W, Featherstone JD (2005) Prevention of enamel demineralization: an in-vitro study using light-cured filled sealant. Am J Orthod Dentofac Orthop 128:592–600CrossRef Hu W, Featherstone JD (2005) Prevention of enamel demineralization: an in-vitro study using light-cured filled sealant. Am J Orthod Dentofac Orthop 128:592–600CrossRef
37.
Zurück zum Zitat Pus MD, Way DC (1980) Enamel loss due to orthodontic bonding with filled and unfilled resins using various clean-up techniques. Am J Orthod 77:269–283CrossRefPubMed Pus MD, Way DC (1980) Enamel loss due to orthodontic bonding with filled and unfilled resins using various clean-up techniques. Am J Orthod 77:269–283CrossRefPubMed
38.
Zurück zum Zitat Brown CL, Way DC (1978) Enamel loss during orthodontic bonding and subsequent loss during removal of filled and unfilled adhesives. Am J Orthod 74:663–671CrossRefPubMed Brown CL, Way DC (1978) Enamel loss during orthodontic bonding and subsequent loss during removal of filled and unfilled adhesives. Am J Orthod 74:663–671CrossRefPubMed
39.
Zurück zum Zitat Bradshaw D, Marsh P, Hodgson R, Visser J (2002) Effects of glucose and fluoride on competition and metabolism within in vitro dental bacterial communities and biofilms. Caries Res 36:81–86CrossRefPubMed Bradshaw D, Marsh P, Hodgson R, Visser J (2002) Effects of glucose and fluoride on competition and metabolism within in vitro dental bacterial communities and biofilms. Caries Res 36:81–86CrossRefPubMed
40.
Zurück zum Zitat Erdem A, Sepet E, Kulekci G, Trosola S, Guven Y (2012) Effects of two fluoride varnishes and one fluoride/chlorhexidine varnish on Streptococcus mutans and Streptococcus sobrinus biofilm formation in vitro. Int J Med Sci 9:129–136CrossRef Erdem A, Sepet E, Kulekci G, Trosola S, Guven Y (2012) Effects of two fluoride varnishes and one fluoride/chlorhexidine varnish on Streptococcus mutans and Streptococcus sobrinus biofilm formation in vitro. Int J Med Sci 9:129–136CrossRef
41.
Zurück zum Zitat Banks P, Chadwick S, Asher-McDade C, Wright J (2000) Fluoride-releasing elastomerics—a prospective controlled clinical trial. Eur J Orthod 22:401–407CrossRefPubMed Banks P, Chadwick S, Asher-McDade C, Wright J (2000) Fluoride-releasing elastomerics—a prospective controlled clinical trial. Eur J Orthod 22:401–407CrossRefPubMed
42.
Zurück zum Zitat Soliman MM, Bishara SE, Wefel J, Heilman J, Warren JJ (2006) Fluoride release rate from an orthodontic sealant and its clinical implications. Angle Orthod 76:282–288PubMed Soliman MM, Bishara SE, Wefel J, Heilman J, Warren JJ (2006) Fluoride release rate from an orthodontic sealant and its clinical implications. Angle Orthod 76:282–288PubMed
43.
Zurück zum Zitat Damon PL, Bishara SE, Olsen ME, Jakobsen JR (1996) Effects of fluoride application on shear bond strength of orthodontic brackets. Angle Orthod 66:61–64PubMed Damon PL, Bishara SE, Olsen ME, Jakobsen JR (1996) Effects of fluoride application on shear bond strength of orthodontic brackets. Angle Orthod 66:61–64PubMed
44.
Zurück zum Zitat Keçik D, Cehreli SB, Sar Ç, Ünver B (2008) Effect of acidulated phosphate fluoride and casein phosphopeptide-amorphous calcium phosphate application on shear bond strength of orthodontic brackets. Angle Orthod 78:129–133CrossRefPubMed Keçik D, Cehreli SB, Sar Ç, Ünver B (2008) Effect of acidulated phosphate fluoride and casein phosphopeptide-amorphous calcium phosphate application on shear bond strength of orthodontic brackets. Angle Orthod 78:129–133CrossRefPubMed
45.
Zurück zum Zitat Kimura T, Dunn WJ, Taloumis LJ (2004) Effect of fluoride varnish on the in vitro bond strength of orthodontic brackets using a self-etching primer system. Am J Orthod Dentofac Orthop 125:351–356CrossRef Kimura T, Dunn WJ, Taloumis LJ (2004) Effect of fluoride varnish on the in vitro bond strength of orthodontic brackets using a self-etching primer system. Am J Orthod Dentofac Orthop 125:351–356CrossRef
46.
Zurück zum Zitat Cacciafesta V, Sfondrini MF, Calvi D, Scribante A (2005) Effect of fluoride application on shear bond strength of brackets bonded with a resin-modified glass-ionomer. Am J Orthod Dentofac Orthop 127:580–583CrossRef Cacciafesta V, Sfondrini MF, Calvi D, Scribante A (2005) Effect of fluoride application on shear bond strength of brackets bonded with a resin-modified glass-ionomer. Am J Orthod Dentofac Orthop 127:580–583CrossRef
47.
Zurück zum Zitat Bishara SE, Oonsombat C, Soliman MM, Warren J (2005) Effects of using a new protective sealant on the bond strength of orthodontic brackets. Angle Orthod 75:243–246PubMed Bishara SE, Oonsombat C, Soliman MM, Warren J (2005) Effects of using a new protective sealant on the bond strength of orthodontic brackets. Angle Orthod 75:243–246PubMed
Metadaten
Titel
Comparing the effects of three different fluoride-releasing agents on white spot lesion prevention in patients treated with full coverage rapid maxillary expanders
verfasst von
Yasemin Nur Korkmaz
Ahmet Yagci
Publikationsdatum
28.11.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Oral Investigations / Ausgabe 8/2019
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-018-2749-7

Weitere Artikel der Ausgabe 8/2019

Clinical Oral Investigations 8/2019 Zur Ausgabe

Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Zahnmedizin und bleiben Sie gut informiert – ganz bequem per eMail.