Background
Methods
Data collection
Statistical analysis
Cognitive discourse analysis (CODA)
Results
Subjects
Sample of individuals aged ≤30 (n = 624) | Sample of individuals aged >30 (n = 303) | Overall sample (n = 927) | PT general population aged 18–30 (N = 1.524.869)a
| |
---|---|---|---|---|
Mean age (SD) | 21.7 (3.2) | 38.1 (6.3) | 25.5 (8.1) | 24.1 (3.7) |
% women | 60.4 | 61.1 | 60.6 | 49.6 |
% single | 93.8 | 49.5 | 79.4 | 63.0 |
% without a chronic diseaseb
| 82.2 | 78.9 | 81.1 | 69.2 |
Mean EQ-5D-5L (SD) | 0.896 (0.119) | 0.889 (0.133) | 0.894 (0.124) | n.a. |
Mean EQ-5D-3L (SD)c
| 0.919 (0.114) | 0.907 (0.123) | 0.915 (0.117) | 0.758 (SE-0.006) |
Mean EQ-5D VAS (SD)c
| 84.7 (12.1) | 82.3 (13.6) | 83.9 (12.7) | 74.9 (SE-0.504) |
Feasibility
Sample aged ≤30 (n = 624) | Sample aged >30 (n = 303) | Overall sample (n = 927) | ||||
---|---|---|---|---|---|---|
Dimension | EQ-5D-3L | EQ-5D-5L | EQ-5D-3L | EQ-5D-5L | EQ-5D-3L | EQ-5D-5L |
Mobility | 2 (0.3 %) | 2 (0.3 %) | 3 (1.0 %) | 0 (0.0 %) | 5 (0.5 %) | 2 (0.2 %) |
Self-care | 4 (0.6 %) | 2 (0.3 %) | 8 (2.6 %) | 0 (0.0 %) | 12 (1.3 %) | 2 (0.2 %) |
Usual Activities | 5 (0.8 %) | 1 (0.2 %) | 5 (1.7 %) | 1 (0.3 %) | 10 (1.1 %) | 2 (0.2 %) |
Pain/Discomfort | 10 (1.6 %) | 1 (0.2 %) | 6 (2.0 %) | 0 (0.0 %) | 16 (1.7 %) | 1 (0.1 %) |
Anxiety/Depression | 8 (1.3 %) | 1 (0.2 %) | 9 (3.0 %) | 1 (0.3 %) | 17 (1.8 %) | 2 (0.2 %) |
Inconsistency
Mobility | Self-care | ||||||||||||
5L | 5L | ||||||||||||
3L | 1 | 2 | 3 | 4 | 5 | Σ | 3L | 1 | 2 | 3 | 4 | 5 | Σ |
1 | 597 | 6 |
0
|
1
|
2
| 606 | 1 | 615 | 0 |
0
|
0
|
0
| 615 |
2 |
1
| 10 | 2 | 1 |
0
| 14 | 2 |
0
| 2 | 1 | 0 |
0
| 3 |
3 |
0
|
0
|
0
| 0 | 0 | 0 | 3 |
0
|
0
|
0
| 0 | 0 | 0 |
Σ | 598 | 16 | 2 | 2 | 2 | 620 | Σ | 615 | 2 | 1 | 0 | 0 | 618 |
Spearman | 0.732* | Spearman | 1.000* | ||||||||||
Usual Activities | Pain/Discomfort | ||||||||||||
5L | 5L | ||||||||||||
3L | 1 | 2 | 3 | 4 | 5 | Σ | 3L | 1 | 2 | 3 | 4 | 5 | Σ |
1 | 574 | 12 |
0
|
0
|
0
| 586 | 1 | 424 | 68 |
0
|
0
|
0
| 492 |
2 |
1
| 26 | 2 | 3 |
0
| 32 | 2 |
3
| 100 | 16 | 1 |
0
| 120 |
3 |
0
|
0
|
0
| 0 | 0 | 0 | 3 |
0
|
0
|
0
| 0 | 1 | 1 |
Σ | 575 | 38 | 2 | 3 | 0 | 618 | Σ | 427 | 168 | 16 | 1 | 1 | 613 |
Spearman | 0.828* | Spearman | 0.739* | ||||||||||
Anxiety/Depression | Summary of inconsistencies | ||||||||||||
5L | Dimension | n° (%) | Average | ||||||||||
3L | 1 | 2 | 3 | 4 | 5 | Σ | Mobility | 4 (0.6 %) | 2.3 | ||||
1 | 374 | 65 |
3
|
0
|
0
| 442 | Self-care | 0 (0.0 %) | - | ||||
2 |
4
| 118 | 44 | 5 |
1
| 172 | Usual Activities | 1 (0.2 %) | 1.0 | ||||
3 |
0
|
0
|
0
| 1 | 0 | 1 | Pain/Discomfort | 3 (0.5 %) | 1.0 | ||||
Σ | 378 | 183 | 47 | 6 | 1 | 615 | Anxiety/Depression | 8 (1.3 %) | 1.0 | ||||
Spearman | 0.780* |
Ceiling effect
Sample aged ≤30 (n = 624) | Sample aged >30 (n = 303) | Overall sample (n = 927) | Sample aged ≤30 (n = 624) | Sample aged >30 (n = 303) | Overall sample (n = 927) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3L | 5L |
p
a
| 3L | 5L |
p
a
| 3L | 5L |
p
a
| Absolute | Relative (%) | Absolute | Relative (%) | Absolute | Relative (%) | |
FH | 376 (62.1 %) | 288 (46.4 %) | 0.001 | 168 (58.7 %) | 141 (46.8 %) | 0.001 | 544 (61.1 %) | 429 (46.5 %) | 0.001 | 15.7 % | 25.3 % | 11.9 % | 20.3 % | 14.6 % | 23.9 % |
MO | 608 (97.7 %) | 600 (96.5 %) | 0.021 | 286 (95.3 %) | 285 (94.1 %) | 0.250 | 894 (97.0 %) | 885 (95.7 %) | 0.003 | 1.2 % | 1.2 % | 1.2 % | 1.3 % | 1.3 % | 1.3 % |
SC | 617 (99.5 %) | 619 (99.5 %) | 1.000 | 293 (99.3 %) | 300 (99.0 %) | 1.000 | 910 (99.5 %) | 919 (99.4 %) | 1.000 | 0.0 % | 0.0 % | 0.3 % | 0.3 % | 0.1 % | 0.1 % |
UA | 587 (94.8 %) | 580 (93.1 %) | 0.003 | 281 (94.3 %) | 274 (90.7 %) | 0.013 | 868 (94.7 %) | 854 (92.3 %) | 0.001 | 1.7 % | 1.8 % | 3.6 % | 3.8 % | 2.4 % | 2.5 % |
PD | 493 (80.3 %) | 428 (68.7 %) | 0.001 | 220 (74.1 %) | 196 (64.7 %) | 0.001 | 713 (78.3 %) | 624 (67.4 %) | 0.001 | 11.6 % | 14.4 % | 9.4 % | 12.7 % | 10.9 % | 13.9 % |
AD | 443 (71.9 %) | 382 (61.3 %) | 0.001 | 216 (73.5 %) | 190 (62.9 %) | 0.001 | 659 (72.4 %) | 572 (61.8 %) | 0.001 | 10.6 % | 14.7 % | 10.6 % | 14.4 % | 10.6 % | 14.6 % |
Level of agreement
Known-groups validity
Discriminative properties
EQ-5D-5L | EQ-5D-3L | |||||
---|---|---|---|---|---|---|
Reported medical conditions | AUC | 95 % CI | AUC | 95 % CI |
χ
2
|
p
|
None versus 1 or more conditions | 0.382 | 0.323;0.441 | 0.383 | 0.328; 0.438 | 0.00 | 0.946 |
None or 1 condition versus 2 or more conditions | 0.274 | 0.164; 0.383 | 0.270 | 0.168; 0.372 | 0.02 | 0.892 |
Content and linguistic analysis of explorative interviews
Dimensions & levels of severity | Sample quotes (content analysis) | Linguistic extracts | Linguistic features | |
---|---|---|---|---|
Mobility | slight |
Minimal problems
|
Maybe, I don’t know
| Illustrations, moderate level of certainty |
Pain is not strong
|
For example
| |||
Someone who limps
|
I would say that
| |||
I sprayed my ankle, but I can still walk
|
I don’t see any difference between moderate and severe
| |||
Something like that
| ||||
moderate |
Sprayed an ankle and need a clutch
|
A moderate problem
| Repetition | |
His problem is slightly more severe, for example instead of limping the leg is paralyzed
|
For example
| Illustration | ||
Moderate is a bit more…[does not complete sentence] | ||||
Self-care | slight |
People who have problems in washing their teeth
| [long pause and difficulties in distinguishing slight and moderate] | Choice of imprecise qualifiers |
Takes the toothbrush up to the mouth
|
To move is more complicated
| |||
moderate |
They may need external help
|
May need
| Low level of certainty | |
Usual activities | slight |
Tiredness
| Imprecise lexical choice | |
Can practically do everything
|
Can practically do everything
| Generic pronouns | ||
moderate |
Some kind of deficiency
|
Maybe, possibly
| Modalization | |
Is able to do some things
| Some degree of certainty | |||
Pain/Discomfort | Slight |
Something that we can easily change
| Illustration | |
It’s like a itch, we feel but we don’t give it too much thought
| High level of certainty | |||
I feel some discomfort right now ‘cause of my allergies
| ||||
moderate |
Some kind of illness, the flu
|
[no occurrence of modals, and mitigators]
| High level of certainty | |
We feel it is hurting in a given place
| ||||
Slight [discomfort] is more superficial it’s not so exaggerated
| ||||
Moderate is like the name indicates the person can do some things and others can’t
| ||||
Anxiety/Depression | slight |
I’m slightly [anxious] during [school] tests
|
I’m slightly [anxious] during [school] tests
| High level of certainty |
A person has the notion s/he is anxious but it does not impacts on the way s/he acts and speaks
|
I’m slightly anxious to know my grade
| Choice of lexical nouns specific | ||
When we’re going to take a harder [school] test
| ||||
moderate |
On the day of the test I’m moderately anxious, it’s not severe
|
On the day of the test I’m moderately anxious may start to stutter
| High degree of certainty | |
A moderately anxious person may start to stutter
| Illustration with own feelings and own context | |||
Choice of specific lexical items | ||||
severe |
An extremely anxious person might even I don’t know have panic attacks
|
might even I don’t know
| Moderate to high level of certainty | |
Choice of specific lexical items | ||||
The person shuts himself/herself at home doesn’t want to see anyone thinks only of committing suicide
|
Items | Content analysisa
| Linguistic extractsa
| Linguistic features |
---|---|---|---|
Pain/Discomfort |
I think pain is something that pains us and discomfort is that we don’t feel 100 % [3] | Choice of generic lexical items and indefinite pronouns | |
To measure the degree of pain is very difficult [2] |
For me pain is to feel some pain, right? Discomfort is to feel bothered with something but it’s not really pain [4] | High level of certainty | |
Anxiety/Depression |
These are totally different things [1] |
When I’m depressed I’m sad, I don’t feel like doing anything
| First person discourse |
These are two distinct things [3] |
I think there are various types of anxiety but there’s only one type of depression [2] | Choice of specific lexical items | |
These are two different issues [4] | High level of certainty |