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30.04.2018 | Retinal Disorders | Ausgabe 7/2018

Graefe's Archive for Clinical and Experimental Ophthalmology 7/2018

Comparison between wide-angle OCT angiography and ultra-wide field fluorescein angiography for detecting non-perfusion areas and retinal neovascularization in eyes with diabetic retinopathy

Zeitschrift:
Graefe's Archive for Clinical and Experimental Ophthalmology > Ausgabe 7/2018
Autoren:
Osamu Sawada, Yusuke Ichiyama, Syunpei Obata, Yuka Ito, Masashi Kakinoki, Tomoko Sawada, Yoshitsugu Saishin, Masahito Ohji
Wichtige Hinweise

Electronic supplementary material

The online version of this article (https://​doi.​org/​10.​1007/​s00417-018-3992-y) contains supplementary material, which is available to authorized users.
The authors have no proprietary interest in any aspect of this study.

Abstract

Purpose

To compare the ability of wide-angle optical coherence tomography angiography (OCTA) with that of ultra-wide field fluorescein angiography (UWFFA) to detect non-perfusion areas (NPAs) or retinal neovascularization (NV) in eyes with diabetic retinopathy (DR).

Methods

Patients with DR underwent UWFFA using the Optos® panoramic 200Tx imaging system and wide-angle OCTA with 12 × 12 mm fields of five visual fixations using the PLEX Elite 9000®. We compared the abilities of UWFFA and OCTA to detect NPAs and NV.

Results

Fifty-eight eyes of 33 patients (mean age, 60.0 years old; female/male, 16/17) with DR were evaluated. NPAs were detected in 47 out of 58 eyes using UWFFA and in 48 eyes using OCTA. NVs were detected in 25 out of the 58 eyes using UWFFA and in 26 eyes using OCTA. The sensitivity for detection of NPA using OCTA was 0.98, and the specificity was 0.82. The sensitivity for detection of NV was 1.0, and the specificity was 0.97.

Conclusion

The wide-angle OCTA seems to be clinically useful for the detection of NPAs or NV.

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Zusatzmaterial
ESM 1 (ZIP 196962 kb)
417_2018_3992_MOESM1_ESM.zip
Literatur
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