Introduction
Methods
Study population
Catheter procedure
Post-PCI management
Study endpoints and definition
Angiographic analysis
Statistical analysis
Results
Baseline clinical, angiographic, and procedural characteristics
0.9 mm (n = 51) | 1.4 mm (n = 39) | p value | |
---|---|---|---|
Diagnosis | 0.59 | ||
STEMI | 43 (84.3) | 31 (79.5) | |
NSTEMI | 8 (15.7) | 8 (20.5) | |
Age (years) | 67.4 ± 15.1 | 66.1 ± 13.8 | 0.68 |
Male | 43 (84.3) | 29 (74.4) | 0.29 |
Hypertension | 25 (49.0) | 21 (53.8) | 0.68 |
Diabetes mellitus | 16 (31.4) | 13 (33.3) | 1.0 |
Dyslipidemia | 28 (54.9) | 23 (59.0) | 0.83 |
Smoking | 32 (62.7) | 21 (53.8) | 0.52 |
History of PCI | 7 (13.7) | 7 (17.9) | 0.77 |
History of CABG | 2 (3.9) | 0 (0) | 0.50 |
Killip class 1–2 | 43 (84.3) | 31 (79.5) | 0.59 |
LVEF before PCI (%) | 49.1 ± 11.3 | 53.4 ± 13.4 | 0.11 |
Onset to device time (min) | 314.2 ± 262.5 | 394.2 ± 296.0 | 0.18 |
Peak CK (IU/L) | 2581 ± 2147 | 2656 ± 1975 | 0.87 |
Peak CK-MB (IU/L) | 224 ± 181 | 271 ± 276 | 0.34 |
0.9 mm (n = 51) | 1.4 mm (n = 39) | p value | |
---|---|---|---|
Culprit lesion | 0.02 | ||
LAD | 32 (62.7) | 17 (43.6) | |
LCX | 2 (3.9) | 9 (23.1) | |
RCA | 17 (33.3) | 13 (33.3) | |
LMT | 0 (0) | 0 (0) | |
Lesion type | 0.63 | ||
A/B1 | 3 (5.9) | 1 (2.6) | |
B2/C | 48 (94.1) | 38 (97.4) | |
Number of diseased vessels (n) | 1.56 ± 0.81 | 1.49 ± 0.72 | 0.62 |
Baseline TIMI grade | 0.74 | ||
0–1 | 28 (54.9) | 24 (61.5) | |
2 | 14 (27.5) | 8 (20.5) | |
3 | 9 (17.6) | 7 (17.9) | |
Pre ELCA TIMI grade | 0.81 | ||
0–1 | 13 (25.5) | 8 (20.5) | |
2 | 20 (39.2) | 15 (38.5) | |
3 | 18 (35.3) | 16 (41.0) | |
Post-ELCA TIMI grade | 0.64 | ||
0–1 | 11 (21.6) | 6 (15.4) | |
2 | 12 (23.5) | 12 (30.8) | |
3 | 28 (54.9) | 21 (54.4) |
0.9 mm (n = 51) | 1.4 mm (n = 39) | p value | |
---|---|---|---|
Stent implantation | 48 (94.1) | 31 (79.5) | 0.05 |
Stent size (mm) | 3.29 ± 0.58 | 3.32 ± 0.45 | 0.78 |
Stent length (mm) | 34.2 ± 15.0 | 30.8 ± 16.0 | 0.34 |
Direct stenting | 34 (66.7) | 21 (53.8) | 0.28 |
Thrombus aspiration | 22 (43.1) | 25 (64.1) | 0.06 |
Distal protection | 2 (3.9) | 2 (5.1) | 1.0 |
Vasodilator | 21 (41.2) | 17 (43.6) | 0.83 |
IABP | 6 (11.8) | 6 (15.4) | 0.76 |
Maximum fluence (mJ/mm2) | 56.8 ± 6.6 | 53.9 ± 6.3 | 0.04 |
Maximum repetition (Hz) | 36.9 ± 6.6 | 33.8 ± 6.2 | 0.03 |
Evaporation time of excimer laser (s) | 395.5 ± 229.2 | 408.1 ± 330.5 | 0.84 |
Timing of ELCA | 0.43 | ||
Direct ELCA | 31 (60.8) | 19 (48.7) | |
Post-thrombus aspiration | 18 (35.3) | 19 (48.7) | |
Post-balloon dilatation | 2 (3.9) | 1 (2.6) |
QCA results
0.9 mm (n = 51) | 1.4 mm (n = 39) | p value | |
---|---|---|---|
Baseline QCA data | |||
Lesion length (mm) | 22.4 ± 12.3 | 18.2 ± 9.1 | 0.09 |
Reference diameter (mm) | 2.70 ± 0.73 | 2.56 ± 0.64 | 0.36 |
MLD (mm) | 0.67 ± 0.27 | 0.63 ± 0.37 | 0.59 |
%DS (%) | 74.2 ± 10.7 | 74.5 ± 13.5 | 0.92 |
Plaque burden (mm3) | 50.8 ± 47.8 | 41.8 ± 27.5 | 0.32 |
Acute gain after ELCA (mm) | 0.23 ± 0.44 | 0.26 ± 0.41 | 0.82 |
Plaque reduction after ELCA (mm3) | 11.8 ± 20.6 | 13.9 ± 21.7 | 0.68 |
Final QCA data | |||
MLD (mm) | 2.67 ± 0.82 | 2.59 ± 0.78 | 0.62 |
%DS (%) | 13.9 ± 9.2 | 14.3 ± 17.2 | 0.90 |
Plaque burden (mm3) | 13.5 ± 15.7 | 22.6 ± 36.6 | 0.12 |
Procedural and angiographic results
0.9 mm (n = 51) | 1.4 mm (n = 39) | p value | |
---|---|---|---|
Procedural success | 43 (84.3) | 34 (87.2) | 0.77 |
Lesion crossability | 50 (98.0) | 35 (89.7) | 0.16 |
ELCA complications | 4 (7.8) | 6 (15.4) | 0.32 |
Perforation | 0 (0) | 0 (0) | n.s |
Slow flow or no-reflow | 3 (5.9) | 5 (12.8) | 0.29 |
Side branch occlusion | 0 (0) | 0 (0) | n.s |
Major dissection | 1 (2.0) | 0 (0.0) | 1.0 |
Ulceration | 0 (0) | 1 (2.6) | 0.43 |
Post-PCI complications | 0 | 0 | n.s |