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Surgical Endoscopy
Erschienen in:

06.07.2020

Comparison of clinical outcomes and quality of life between laparoscopic distal pancreatectomy with or without spleen preservation

verfasst von: Ren-Chao Zhang, Jun Ma, Yi-Ping Mou, Jia-Fei Yan, Yu-Cheng Zhou

Erschienen in: Surgical Endoscopy | Ausgabe 7/2021

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Abstract

Background

The studies comparing laparoscopic spleen-preserving distal pancreatectomy (LSPDP) and laparoscopic distal pancreatosplenectomy (LDPS) are limited. This study aimed to compare clinical outcomes and quality of life of patients undergoing LSPDP and LDPS.

Methods

Between March 2004 and December 2014, patients who underwent laparoscopic distal pancreatectomy were reviewed. Patients were divided into 2 groups as LSPDP and LDPS. Data considered for comparison analysis were patient demographics, intraoperative variables, morbidity, postoperative hospital stay, mortality, pathologic findings, and quality of life (SF-36 questionnaire).

Results

A total of 110 patients (50 LSPDP and 60 LDPS) were included in the final analysis. Baseline characteristics were similar in the 2 groups. The LSPDP group had a significantly shorter operative time(153.3 ± 46.2 vs. 179.9 ± 54.1 min, p = 0.015) than the LDPS group. Also in analysis of propensity-matched population(LSPDP:LDPS = 35:35, 1:1 matching), LSPDP group still had a significantly shorter operative time (159.3 ± 36.2 vs. 172.9 ± 44.1 min, p = 0.045) than the LDPS group.There were no significant differences with respect to estimated blood loss, first flatus time, diet start time, and postoperative hospital stay. Postoperative outcomes, including morbidity, pancreatic fistula rates, and mortality, were similar in the LSPDP and LDPS group. On the follow-up survey, the total quality of life score (635.8 ± 50.7 vs. 596.1 ± 92.1)was higher in the LSPDP group compared with the LDPS group. However, the differences were not statistically significant(p > 0.05). The score in vitality (82.5 ± 14.4 vs. 68.9 ± 11.4, p = 0.046) was significantly higher in LSPDP group and not statistically significant in other areas (p > 0.05).Similar results of quality of life assessment were found in analysis of propensity-matched population.

Conclusions

Compared to LDPS, LSPDP had shorter operating time and better quality of life with similar morbidity and recovery period.
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Metadaten
Titel
Comparison of clinical outcomes and quality of life between laparoscopic distal pancreatectomy with or without spleen preservation
verfasst von
Ren-Chao Zhang
Jun Ma
Yi-Ping Mou
Jia-Fei Yan
Yu-Cheng Zhou
Publikationsdatum
06.07.2020
Verlag
Springer US
Erschienen in
Surgical Endoscopy / Ausgabe 7/2021
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-020-07783-2

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