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Erschienen in:

28.08.2024 | Urologic Oncology

Comparison of Complications and Mid-term Results for Patients who Underwent Open Radical Prostatectomy for High-Risk and Oligometastatic Prostate Cancer: A Cross-Sectional Study from a Tertiary Reference Center

verfasst von: Murat Beyatlı, MD, Mehmet Duvarci, MD, Tuncel Uzel, MD, Halil Çağrı Aybal, MD, Nurullah Hamidi, MD, Oğuzhan Ceylan, MD, Emrah Çağlar, MD, Halil Basar, MD

Erschienen in: Annals of Surgical Oncology | Ausgabe 12/2024

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Abstract

Background

This study aimed to evaluate perioperative complications and oncologic results for high-risk and oligometastatic prostate cancer patients.

Methods

The data of patients who underwent surgery for prostate cancer in the authors’ clinic between January 2012 and March 2022 were analyzed retrospectively. According to D’amico classification, 28 patients with high-risk prostate cancer and 23 patients in the oligometastatic stage were included in the study. The patients were divided into two groups: group 1 (high-risk prostate cancers) and group 2 (oligometastatic cancer). Demographic characteristics, oncologic data, pathologic data, and complications of the patients were recorded.

Results

The mean age of the patients was 67.84 years (range, 52–79 years). The average follow-up period was 45.48 months for group 1 and 46.36 months for group 2 (p = 0.84). The mean hemoglobin decrease was 1.53 g/dL in group 1 and 0.69 g/dL in group 2 (p = 0.046). Five patients (17.8%) in group 1 had biochemical recurrence at 14.55 months, whereas three patients (13%) in group 2 had biochemical recurrence at 9.87 months (p = 0.646). According to Clavien-Dindo classification, major complications developed in 7.2% of the group 1 patients and in 8.6% of the group 2 patients. Surgical margin positivity was detected in 6 group 1 patients (21.4%) and 12 group 2 patients (52.2%) (p = 0.023). During the follow-up period, four patients died. Only one of the patients died of cancer.

Conclusion

The authors think that oligometastatic and high-risk prostate cancer surgeries do not differ significantly in terms of complications.
Literatur
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Zurück zum Zitat Recent Global Patterns in Prostate Cancer Incidence and Mortality Rates - PubMed. Recent Global Patterns in Prostate Cancer Incidence and Mortality Rates - PubMed.
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Zurück zum Zitat EAU Guidelines on Prostate Cancer - Uroweb. Uroweb - European Association of Urology. EAU Guidelines on Prostate Cancer - Uroweb. Uroweb - European Association of Urology.
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Zurück zum Zitat Emberton M, Neal DE, Black N, et al. The effect of prostatectomy on symptom severity and quality of life. Br J Urol. 1996;77:233–47.CrossRefPubMed Emberton M, Neal DE, Black N, et al. The effect of prostatectomy on symptom severity and quality of life. Br J Urol. 1996;77:233–47.CrossRefPubMed
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Metadaten
Titel
Comparison of Complications and Mid-term Results for Patients who Underwent Open Radical Prostatectomy for High-Risk and Oligometastatic Prostate Cancer: A Cross-Sectional Study from a Tertiary Reference Center
verfasst von
Murat Beyatlı, MD
Mehmet Duvarci, MD
Tuncel Uzel, MD
Halil Çağrı Aybal, MD
Nurullah Hamidi, MD
Oğuzhan Ceylan, MD
Emrah Çağlar, MD
Halil Basar, MD
Publikationsdatum
28.08.2024
Verlag
Springer International Publishing
Erschienen in
Annals of Surgical Oncology / Ausgabe 12/2024
Print ISSN: 1068-9265
Elektronische ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-024-16104-z

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