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Erschienen in:
01.01.2013 | Original Article
Comparison of FDG-PET, MRI and CT for post radiofrequency ablation evaluation of hepatic tumors
Erschienen in: Annals of Nuclear Medicine | Ausgabe 1/2013
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Purpose
Treatment effect of radiofrequency ablation (RFA) is traditionally accomplished with MRI and/or CT. The aim of the study was to assess the role of FDG-PET in post RFA hepatic tumor evaluation, in comparison with MRI and CT.
Materials and methods
28 patients (33 hepatic RFA lesions) who had post RFA FDG-PET within 8 weeks of abdominopelvic MRI or CT were retrospectively reviewed. Accuracy of FDG-PET on post hepatic RFA evaluation was compared with MRI and/or CT based on clinical and imaging follow-up.
Results
Among total of 33 RFA-treated lesions, 17 had residual or recurrent tumor (positive). PET identified 16 with a sensitivity of 94.1 %. Of these 17 lesions, 12 had concurrent MRI and 8 were positive with a sensitivity of 66.7 %. Similarly, 6 out of the 17 lesions had CT and 4 were positive with a sensitivity of 66.7 %. Sixteen lesions were successfully ablated (negative). Among them FDG-PET was negative in 13 with a specificity of 81.3 %; MRI was performed in 8 and 7 were negative with a specificity of 87.5 %; CT was performed in 8 and 5 were negative with a specificity of 62.5 %. The overall accuracy of PET, MRI and CT was 87.9, 75.0, and 64.3 %, respectively. The average scan numbers for PET, MRI and CT to achieve a final accurate diagnosis were 1.121, 1.316 and 1.250, with a corresponding cost of $1455.2, $1845.8, and $933.8, respectively.
Conclusions
The study suggests that FDG-PET is superior to MRI and/or CT and is more cost-effective in post RFA hepatic tumor assessment.