DT: Invited speaker for Cooper Surgical, Inc. AD: None. GB: Participated in randomized clinical trial of botox vs. Vesicare for Allergan. MA: None. ND: None. AT: None. KC: None. AP: None.
DT: Conception and design, manuscript drafting. AD: Drafting of the manuscript. GB: Study design and manuscript design. MA: Data collection and manuscript revision. ND: Statistical analysis. AT: Data collection and manuscript revision. KC: Data collection and analysis. AP: Study design and manuscript revision. All authors read and approved the final manuscript.
We sought to examine differences in response rates to quality of life (QoL) surveys in patients treated surgically for renal cell carcinoma (RCC) and prostate cancer (PCa) and to analyze factors associated with non-response of the surveys.
Patients who underwent surgery for RCC or PCa between 2006 and 2012 were offered enrollment in respective prospective cancer registries that included baseline and annual QoL assessments. We identified 201 RCC patients and 616 PCa patients who completed a baseline QoL survey and were mailed annual QoL surveys [RCC: SF-36, FACT–G (73 questions), PCa: EPIC, IIEF, Max-PC (80 questions)]. We compared patient characteristics between responders and non-responders using a Wilcoxon rank-sum test for continuous variables and a Fisher’s Exact test for categorical variables.
The overall response rates for the PCa and RCC groups were 63 and 48 % (p < 0.001), respectively. This difference in response rates remained when we limited analysis to only those with early stage disease (pT2 for PCa and pT1 RCC, 62 % vs. 52 %; p = 0.03). PCa characteristics associated with response included older age (64.1 vs 62.6 years, p = 0.032) and robotic versus open surgery (56 % vs 44 %; p = 0.009). There were no characteristics that were associated with response in RCC patients.
Surgically treated PCa patients have higher QoL mail-based survey response rates compared to patients treated surgically for RCC. This difference holds true for clinically localized cancers as well.
Rampersaud EN, Klatte T, Bass G, Patard JJ, Bensaleh K, Böhm M, Allhoff EP, Cindolo L, De La Taille A, Mejean A, Soulie M, Bellec L, Bernhard JC, Pfister C, Colombel M, Belldegrun AS, Pantuck AJ, George D. The effect of gender and age on kidney cancer survival: younger age is an independent prognostic factor in women with renal cell carcinoma. Urol Oncol. 2014;32:30.e9–30.e13.
Kibel AS, Ciezki JP, Klein EA, Reddy CA, Lubahn JD, Haslag-Minoff J, Deasy JO, Michalski JM, Kallogjeri D, Piccirillo JF, Rabah DM, Yu C, Kattan MW, Stephenson AJ. Survival among men with clinically localized prostate cancer treated with radical prostatectomy or radiation therapy in the prostate specific antigen era. J Urol. 2012;187:1259–65.
Gazmararian JA, Baker DW, Williams MV, Parker RM, Scott TL, Green DC, Fehrenbach N, Ren J, Koplan JP. Health literacy among Medicare enrollees in a managed care organization. JAMA. 1999;281:545–51.
Kim SP, Karnes RJ, Nguyen PL, Ziegenfuss JY, Han LC, Thompson RH, Trinh QD, Sun M, Boorjian SA, Beebe TJ, Tilburt JC. Clinical implementation of quality of life instruments and prediction tools for localized prostate cancer: results from a national survey of radiation oncologists and urologists. J Urol. 2013;189:2092–8.
Ware JE, Snow KK, Kosinsnki M, et al. SF-36 health survey manual and interpretation guide. Boston, MA: The Health Institute, New England Medical Center Hospitals; 1993.
Roth AJ, Rosenfeld B, Kornblith AB, Gibson C, Scher HI, Curley-Smart T, Holland JC, Breitbart W. The memorial anxiety scale for prostate cancer validation of a new scale to measure anxiety in men with with prostate cancer. Cancer. 2003;1;97:2910–8.
Ludovico GM, Dachille G, Pagliarulo G, D’Elia C, Mondaini N, Gacci M, Detti B, Malossini G, Bartoletti R, Cai T. Bilateral nerve sparing robotic-assisted radical prostatectomy is associated with faster continence recovery but not with erectile function recovery compared with retropubic open prostatectomy: the need for accurate selection of patients. Oncol Rep. 2013;29:2445–50.
Beisland C, Beisland E, Hjelle KM, Bostad L, Hjermstad MJ, Aarstad AK, Aarstad HJ. Health-related quality of life in long-term survivors after renal cancer treatments. Scand J Urol. 2014;48:52–64.
Gratzke C, Seitz M, Bayrle F, Schlenker B, Bastian PJ, Haseke N, Bader M, Tilki D, Roosen A, Karl A, Reich O, Khoder WY, Wyler S, Steif CG, Staehler M, Bachmann A. Quality of life and perioperative outcomes after retroperitoneoscopic radical nephrectomy, open RN, and nephron-sparing surgery in patients with renal cell carcinoma. BJU Int. 2009;104:470–5.
- Comparison of patient-reported quality of life outcome questionnaire response rates between patients treated surgically for renal cell carcinoma and prostate carcinoma
David D. Thiel
Andrew J. Davidiuk
Gregory A. Broderick
Alexander S. Parker
- BioMed Central
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