Erschienen in:
18.05.2016 | Original contribution
Comparison of prevalence of obstructive sleep apnea, restless legs syndrome, and poor sleep quality in patients with coronary artery disease and depression
verfasst von:
Dr MD Piyush Srivastava, Dr Ravi Gupta, Dr Damodar Chari, Dr Anurag Rawat, Dr Deepak Goel
Erschienen in:
Somnologie
|
Ausgabe 2/2016
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Abstract
Background
This study was designed to compare the prevalence of restless leg syndrome (RLS), obstructive sleep apnea (OSA), and poor sleep quality between patients with coronary artery disease (CAD) and those with major depressive disorder (MDD)/somatic symptom disorder (SSD).
Methods
In this study, subjects with CAD were included. The comparison group consisted of subjects with MDD or SSD. After screening for exclusion criteria, a total of 100 subjects from each group were screened for OSA, RLS, and sleep quality. Hindi versions of the Berlin questionnaire, the Cambridge–Hopkins RLS diagnostic questionnaire, and the Pittsburgh Sleep Quality Index (PSQI) were used for screening, respectively. The groups were compared using statistical tests.
Results
Due to missing data, 33 subjects were excluded from final analysis. Final analysis was performed on 167 subjects—82 with CAD and 85 with MDD/SSD. Males outnumbered females in this sample (79 % men and 21 % women) and patients with CAD were older (56.1 ± 10.4 years in CAD vs. 35.5 ± 10.9 years in MDD/SSD). Prevalence of “high risk for OSA” was higher among CAD (34 %) as compared to MDD/SSD subjects (12.9 %), even after controlling for age and gender. The prevalence of RLS was comparable (13.4 % in CAD vs. 9.4 % in MDD/SSD). Daytime dysfunction, sleep quality, use of medication to induce sleep, and sleep latency were worse in the MDD/SSD group as compared to the CAD group.
Conclusion
In conclusion, this study shows that CAD patients are at a higher risk of OSA, while sleep-related parameters are worse in MDD/SSD patients. RLS was comparable between groups. On the whole, the prevalence of OSA, RLS, and poor sleep quality in both groups was higher as compared to the general population.