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Erschienen in: General Thoracic and Cardiovascular Surgery 12/2023

16.05.2023 | Original Article

Comparison of radiological and pathological tumor sizes in resected non-small cell lung cancer

verfasst von: Taichi Nagano, Shinkichi Takamori, Asato Hashinokuchi, Kyoto Matsydo, Mikihiro Kohno, Naoko Miura, Tomoyoshi Takenaka, Takeshi Kamitani, Mototsugu Shimokawa, Kousei Ishigami, Yoshinao Oda, Tomoharu Yoshizumi

Erschienen in: General Thoracic and Cardiovascular Surgery | Ausgabe 12/2023

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Abstract

Objectives

In non-small cell lung cancer (NSCLC), T factor plays an important role in determining staging. The present study aimed to determine the validity of preoperative evaluation of clinical T (cT) factor by comparing radiological and pathological tumor sizes.

Methods

Data for 1,799 patients with primary NSCLC who underwent curative surgery were investigated. The concordance between cT and pathological T (pT) factors was analyzed. Furthermore, we compared groups with an increase or decrease of ≥ 20% and groups with an increase or decrease of < 20% in the size change between preoperative radiological and pathological diameters.

Results

The mean sizes of the radiological solid components and the pathological invasive tumors were 1.90 cm and 1.99 cm, respectively, correlation degree = 0.782. The group with increased pathological invasive tumor size (≥ 20%) compared with the radiologic solid component was significantly more likely female, consolidation tumor ratio (CTR) ≤ 0.5, and within cT1. Multivariate logistic analysis identified CTR < 1, cT ≤ T1, and adenocarcinoma as independent risk factors for increased pT factor.

Conclusion

The radiological invasive area of tumors with cT1, CTR < 1, or adenocarcinoma on preoperative CT may be underestimated compared with pathological invasive diameter.
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Metadaten
Titel
Comparison of radiological and pathological tumor sizes in resected non-small cell lung cancer
verfasst von
Taichi Nagano
Shinkichi Takamori
Asato Hashinokuchi
Kyoto Matsydo
Mikihiro Kohno
Naoko Miura
Tomoyoshi Takenaka
Takeshi Kamitani
Mototsugu Shimokawa
Kousei Ishigami
Yoshinao Oda
Tomoharu Yoshizumi
Publikationsdatum
16.05.2023
Verlag
Springer Nature Singapore
Erschienen in
General Thoracic and Cardiovascular Surgery / Ausgabe 12/2023
Print ISSN: 1863-6705
Elektronische ISSN: 1863-6713
DOI
https://doi.org/10.1007/s11748-023-01938-3

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