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Erschienen in: Child's Nervous System 6/2014

01.06.2014 | Original Paper

Comparison of subgroups based on hemorrhagic lesions between SWI and FLAIR in pediatric traumatic brain injury

verfasst von: Jong-Il Choi, Bum-Joon Kim, Sung-Kon Ha, Se-Hoon Kim, Dong-Jun Lim, Sang-Dae Kim

Erschienen in: Child's Nervous System | Ausgabe 6/2014

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Abstract

Purpose

The purpose of this study was to investigate efficient ways to diagnose and predict clinical outcomes for childhood traumatic brain injury.

Methods

Hemorrhagic signal intensities in nine brain regions were observed using axial fluid-attenuated inversion recovery (FLAIR) and susceptibility-weighted imaging (SWI). After having divided the subjects into mild presentation (GCS 14–15) and moderate-to-severe presentation groups (GCS ≤13), we divided the patients into three subgroups: Subgroup I, hemorrhagic foci observed only on SWI and not on FLAIR; Subgroup II, hemorrhagic foci observed on both SWI and FLAIR in the same brain regions; and Subgroup III, any cases with additional foci on SWI in other brain regions. We investigated the clinical course and compared lesion numbers and distributions of hemorrhagic lesions on SWI among the subgroups.

Results

Three clinical variables (hospitalization period in intensive care unit, total days of hospitalization, and outcome based on Pediatric Cerebral Performance Category Scale score) showed significant relevance to the three subgroups. Subgroup I showed the fewest lesions followed by Subgroups II and III, respectively. In all three subgroups, lesions were most abundant in cortical regions. Lesion in the thalamus, basal ganglia, corpus callosum, and brainstem was least in Subgroup I and gradually increased in Subgroups II and III. Such distinction was more significant in the moderate-to-severe group when compared with the mild group.

Conclusions

In cases of pediatric traumatic brain injury, categorizing patients into one of the above three subgroups based on hemorrhagic lesions on SWI and FLAIR is a promising method for predicting patient’s clinical outcome.
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Metadaten
Titel
Comparison of subgroups based on hemorrhagic lesions between SWI and FLAIR in pediatric traumatic brain injury
verfasst von
Jong-Il Choi
Bum-Joon Kim
Sung-Kon Ha
Se-Hoon Kim
Dong-Jun Lim
Sang-Dae Kim
Publikationsdatum
01.06.2014
Verlag
Springer Berlin Heidelberg
Erschienen in
Child's Nervous System / Ausgabe 6/2014
Print ISSN: 0256-7040
Elektronische ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-013-2349-4

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