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Erschienen in: Sleep and Breathing 1/2018

19.08.2017 | Sleep Breathing Physiology and Disorders • Original Article

Comparison of two home sleep testing devices with different strategies for diagnosis of OSA

verfasst von: Tyler Gumb, Akosua Twumasi, Shahnaz Alimokhtari, Alan Perez, Kathleen Black, David M. Rapoport, Jag Sunderram, Indu Ayappa

Erschienen in: Sleep and Breathing | Ausgabe 1/2018

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Abstract

Purpose

Home sleep testing devices are being widely used in diagnosis/screening for obstructive sleep apnea (OSA). We examined differences in OSA metrics obtained from two devices with divergent home monitoring strategies, the Apnea Risk Evaluation System (ARES™, multiple signals plus forehead reflectance oximetry) and the Nonin WristOx2™ (single channel finger transmission pulse oximeter), compared to differences from night-night variability of OSA.

Methods

One hundred fifty-two male/26 female subjects (BMI = 30.3 ± 5.6 kg/m2, age = 52.5 ± 8.9 years) were recruited without regard to OSA symptoms and simultaneously wore both ARES™ and Nonin WristOx2™ for two nights (n = 351 nights). Automated analysis of the WristOx2 yielded oxygen desaturation index (ODIOx2, ≥4% O2 dips/h), and automated analysis with manual editing of ARES™ yielded AHI4ARES (apneas + hypopneas with ≥4% O2 dips/h) and RDIARES (apneas + hypopneas with ≥4% O2 dips/h or arousal surrogates). Baseline awake oxygen saturation, percent time < 90% O2 saturation (%time < 90%O2Sat), and O2 signal loss were compared between the two methods.

Results

Correlation between AHI4ARES and ODIOx2 was high (ICC = 0.9, 95% CI = 0.87–0.92, p < 0.001, bias ± SD = 0.7 ± 6.1 events/h). Agreement values for OSA diagnosis (77–85%) between devices were similar to those seen from night-to-night variability of OSA using a single device. Awake baseline O2 saturation was significantly higher in the ARES™ (96.2 ± 1.6%) than WristOx2™ (92.2 ± 2.1%, p < 0.01). There was a significantly lower %time < 90%O2Sat reported by the ARES™ compared to WristOx2 (median (IQR) 0.5 (0.0, 2.6) vs. 2.1 (0.3, 9.7), p < 0.001), and the correlation was low (ICC = 0.2).

Conclusions

OSA severity metrics predominantly dependent on change in oxygen saturation and metrics used in diagnosis of OSA (AHI4 and ODI) correlated well across devices tested. However, differences in cumulative oxygen desaturation measures (i.e., %time < 90%O2Sat) between the devices suggest that caution is needed when interpreting this metric particularly in populations likely to have significant hypoxia.
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Metadaten
Titel
Comparison of two home sleep testing devices with different strategies for diagnosis of OSA
verfasst von
Tyler Gumb
Akosua Twumasi
Shahnaz Alimokhtari
Alan Perez
Kathleen Black
David M. Rapoport
Jag Sunderram
Indu Ayappa
Publikationsdatum
19.08.2017
Verlag
Springer International Publishing
Erschienen in
Sleep and Breathing / Ausgabe 1/2018
Print ISSN: 1520-9512
Elektronische ISSN: 1522-1709
DOI
https://doi.org/10.1007/s11325-017-1547-9

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