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29.04.2017 | Original Contribution

Comparison of urinary iodine levels in women of childbearing age during and after pregnancy

verfasst von: Ane Miren Castilla, Mario Murcia, Juan José Arrizabalaga, Mercedes Espada, Jordi Julvez, Mikel Basterrechea, Mar Alvarez-Pedrerol, Marisa Estarlich, Elena Moreno, Mònica Guxens, Jesús Vioque, Marisa Rebagliato

Erschienen in: European Journal of Nutrition | Ausgabe 5/2018

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Abstract

Purpose

Median urinary iodine concentration (UIC) is used to describe the iodine status of a population. However, the link between UIC and iodine intake may vary during pregnancy. The aim of this study was to compare UIC during and after pregnancy, adjusting for factors that affect iodine intake.

Methods

Two repeated measures of UIC and data on maternal iodine intake estimated through questionnaires were collected during pregnancy and 1–4 years after pregnancy in a subsample of women (n = 598) from a mother and child cohort study in Spain. Random-effects interval regression was used to assess the changes in UIC according to pregnancy status.

Results

Median UIC was similar during (133 μg/L) and after pregnancy (139 μg/L). After adjusting for iodised salt, iodine supplement consumption, and socio-demographic related variables, UIC was 24.0% (95% CI 11.3, 38.2) higher after than during pregnancy. This difference was maintained in a subsample of women with exhaustive information on diet (n = 291): 26.2%, 95% CI 10.3, 44.4.

Conclusions

In an iodine sufficient area for the general population, iodine excretion was lower during than after pregnancy when factors affecting iodine intake were controlled for. Current recommendations of median UIC during pregnancy are based on the equivalence between iodine intake and UIC estimated from studies in non-pregnant populations, which might lead to overestimation of iodine deficiency during gestation. Further studies should evaluate the equivalence between iodine intake and its urinary excretion during pregnancy.

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Titel: Comparison of urinary iodine levels in women of childbearing age during and after pregnancy
verfasst von: Ane Miren Castilla
Mario Murcia
Juan José Arrizabalaga
Mercedes Espada
Jordi Julvez
Mikel Basterrechea
Mar Alvarez-Pedrerol
Marisa Estarlich
Elena Moreno
Mònica Guxens
Jesús Vioque
Marisa Rebagliato
Publikationsdatum: 29.04.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: European Journal of Nutrition / Ausgabe 5/2018
Print ISSN: 1436-6207
Elektronische ISSN: 1436-6215
DOI: https://doi.org/10.1007/s00394-017-1465-4

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Comparison of urinary iodine levels in women of childbearing age during and after pregnancy

Abstract

Purpose

Methods

Results

Conclusions

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