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Erschienen in: Archives of Virology 6/2016

03.03.2016 | Annotated Sequence Record

Complete genome analysis of coxsackievirus A24 isolated in Yunnan, China, in 2013

verfasst von: Yilin Zhao, Jiansheng Liu, Haihao Zhang, Chen Guo, Longhui Xia, Fang Yang, Huai Yang, Qinxing Yang, Zhaoqing Yang, Shaohui Ma

Erschienen in: Archives of Virology | Ausgabe 6/2016

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Abstract

Human coxsackievirus A24 (CVA24) belongs to the species Enterovirus C, and variants of this virus frequently cause acute hemorrhagic conjunctivitis (AHC). The complete genome of the K282/YN/CHN/2013 strain, isolated from a healthy child in Yunnan, China, in 2013, is reported here for the first time. The strain showed 80.0 % and 79.9 % nucleotide sequence identity to CVA24 prototype strain Joseph and CVA24 variant prototype EH24, respectively. The K282/YN/CHN/2013 strain belongs to the CVA24 serotype. Twelve amino acid differences, most of which are in structural regions, were found between the CVA24 and CVA24v strains. In the whole-length genome sequence, only the structural region of K282/YN/CHN/2013 was similar to that of the CVA24 strains; the other genome regions were more similar to those of other members of the species Enterovirus C. Recombination analysis showed evidence of recombination with other viruses of the same species.
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Literatur
1.
Zurück zum Zitat Lo CW, Wu KG, Lin MC, Chen CJ, Ho DM, Tang RB, Chan YJ (2010) Application of a molecular method for the classification of human enteroviruses and its correlation with clinical manifestations. J Microbiol Immunol Infect 43:354–359CrossRefPubMed Lo CW, Wu KG, Lin MC, Chen CJ, Ho DM, Tang RB, Chan YJ (2010) Application of a molecular method for the classification of human enteroviruses and its correlation with clinical manifestations. J Microbiol Immunol Infect 43:354–359CrossRefPubMed
2.
Zurück zum Zitat Brown BA, Maher K, Flemister MR, Naraghi-Arani P, Uddin M, Oberste MS, Pallansch MA (2009) Resolving ambiguities in genetic typing of human enterovirus species C clinical isolates and identification of enterovirus 96, 99 and 102. J Gen Virol 90:1713–1723CrossRefPubMed Brown BA, Maher K, Flemister MR, Naraghi-Arani P, Uddin M, Oberste MS, Pallansch MA (2009) Resolving ambiguities in genetic typing of human enterovirus species C clinical isolates and identification of enterovirus 96, 99 and 102. J Gen Virol 90:1713–1723CrossRefPubMed
3.
Zurück zum Zitat Cabrerizo M, Rabella N, Torner N, Castellanos T, Bustillo I, Varela C, Colomer J, Trallero G (2012) Molecular identification of an enterovirus 99 strain in Spain. Arch Virol 157:551–554CrossRefPubMed Cabrerizo M, Rabella N, Torner N, Castellanos T, Bustillo I, Varela C, Colomer J, Trallero G (2012) Molecular identification of an enterovirus 99 strain in Spain. Arch Virol 157:551–554CrossRefPubMed
4.
Zurück zum Zitat Junttila N, Leveque N, Magnius LO, Kabue JP, Muyembe-Tamfum JJ, Maslin J, Lina B, Norder H (2015) Complete coding regions of the prototypes enterovirus B93 and C95: phylogenetic analyses of the P1 and P3 regions of EV-B and EV-C strains. J Med Virol 87:485–497CrossRefPubMed Junttila N, Leveque N, Magnius LO, Kabue JP, Muyembe-Tamfum JJ, Maslin J, Lina B, Norder H (2015) Complete coding regions of the prototypes enterovirus B93 and C95: phylogenetic analyses of the P1 and P3 regions of EV-B and EV-C strains. J Med Virol 87:485–497CrossRefPubMed
5.
Zurück zum Zitat Rakoto-Andrianarivelo M, Rousset D, Razafindratsimandresy R, Chevaliez S, Guillot S, Balanant J, Delpeyroux F (2005) High frequency of human enterovirus species C circulation in Madagascar. J Clin Microbiol 43:242–249CrossRefPubMedPubMedCentral Rakoto-Andrianarivelo M, Rousset D, Razafindratsimandresy R, Chevaliez S, Guillot S, Balanant J, Delpeyroux F (2005) High frequency of human enterovirus species C circulation in Madagascar. J Clin Microbiol 43:242–249CrossRefPubMedPubMedCentral
6.
Zurück zum Zitat Oberste MS, Maher K, Kilpatrick DR, Pallansch MA (1999) Molecular evolution of the human enteroviruses: correlation of serotype with VP1 sequence and application to picornavirus classification. J Virol 73:1941–1948PubMedPubMedCentral Oberste MS, Maher K, Kilpatrick DR, Pallansch MA (1999) Molecular evolution of the human enteroviruses: correlation of serotype with VP1 sequence and application to picornavirus classification. J Virol 73:1941–1948PubMedPubMedCentral
7.
Zurück zum Zitat Laxmivandana R, Yergolkar P, Rajeshwari M, Chitambar SD (2014) Genomic characterization of coxsackievirus type A24 strains associated with acute flaccid paralysis and rarely identified Hopkins syndrome. Arch Virol 159:3125–3129CrossRefPubMed Laxmivandana R, Yergolkar P, Rajeshwari M, Chitambar SD (2014) Genomic characterization of coxsackievirus type A24 strains associated with acute flaccid paralysis and rarely identified Hopkins syndrome. Arch Virol 159:3125–3129CrossRefPubMed
8.
Zurück zum Zitat Aubry C, Gautret P, Nougairede A, Dussouil AS, Botelho-Nevers E, Zandotti C, De Lamballerie X, Brouqui P, Parola P (2012) 2012 outbreak of acute haemorrhagic conjunctivitis in Indian Ocean Islands: identification of Coxsackievirus A24 in a returned traveller. Euro Surveill 17 Aubry C, Gautret P, Nougairede A, Dussouil AS, Botelho-Nevers E, Zandotti C, De Lamballerie X, Brouqui P, Parola P (2012) 2012 outbreak of acute haemorrhagic conjunctivitis in Indian Ocean Islands: identification of Coxsackievirus A24 in a returned traveller. Euro Surveill 17
9.
Zurück zum Zitat Ayoub EA, Shafik CF, Gaynor AM, Mohareb EW, Amin MA, Yassin AS, El-Refaey S, Genedy M, Kandeel A (2013) A molecular investigative approach to an outbreak of acute hemorrhagic conjunctivitis in Egypt, October 2010. Virol J 10:96CrossRefPubMedPubMedCentral Ayoub EA, Shafik CF, Gaynor AM, Mohareb EW, Amin MA, Yassin AS, El-Refaey S, Genedy M, Kandeel A (2013) A molecular investigative approach to an outbreak of acute hemorrhagic conjunctivitis in Egypt, October 2010. Virol J 10:96CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Fonseca MC, Sarmiento L, Resik S, Pereda N, Rodriguez H, Kouri V, Martinez PA, Pinon A, Limonta D, Mas P, Hung LH (2012) Isolation of Coxsackievirus A24 variant from patients with hemorrhagic conjunctivitis in Cuba, 2008–2009. J Clin Virol 53:77–81CrossRefPubMed Fonseca MC, Sarmiento L, Resik S, Pereda N, Rodriguez H, Kouri V, Martinez PA, Pinon A, Limonta D, Mas P, Hung LH (2012) Isolation of Coxsackievirus A24 variant from patients with hemorrhagic conjunctivitis in Cuba, 2008–2009. J Clin Virol 53:77–81CrossRefPubMed
11.
Zurück zum Zitat Khan A, Sharif S, Shaukat S, Khan S, Zaidi S (2008) An outbreak of acute hemorrhagic conjunctivitis (AHC) caused by coxsackievirus A24 variant in Pakistan. Virus Res 137:150–152CrossRefPubMed Khan A, Sharif S, Shaukat S, Khan S, Zaidi S (2008) An outbreak of acute hemorrhagic conjunctivitis (AHC) caused by coxsackievirus A24 variant in Pakistan. Virus Res 137:150–152CrossRefPubMed
12.
Zurück zum Zitat Leveque N, Amine IL, Cartet G, Hammani AB, Khazraji YC, Lina B, Muyembe JJ, Norder H, Chomel JJ (2007) Two outbreaks of acute hemorrhagic conjunctivitis in Africa due to genotype III coxsackievirus A24 variant. Eur J Clin Microbiol Infect Dis 26:199–202CrossRefPubMed Leveque N, Amine IL, Cartet G, Hammani AB, Khazraji YC, Lina B, Muyembe JJ, Norder H, Chomel JJ (2007) Two outbreaks of acute hemorrhagic conjunctivitis in Africa due to genotype III coxsackievirus A24 variant. Eur J Clin Microbiol Infect Dis 26:199–202CrossRefPubMed
13.
Zurück zum Zitat Nidaira M, Kuba Y, Saitoh M, Taira K, Maeshiro N, Mahoe Y, Kyan H, Takara T, Okano S, Kudaka J, Yoshida H, Oishi K, Kimura H (2014) Molecular evolution of VP3, VP1, 3C(pro) and 3D(pol) coding regions in coxsackievirus group A type 24 variant isolates from acute hemorrhagic conjunctivitis in 2011 in Okinawa, Japan. Microbiol Immunol 58:227–238CrossRefPubMed Nidaira M, Kuba Y, Saitoh M, Taira K, Maeshiro N, Mahoe Y, Kyan H, Takara T, Okano S, Kudaka J, Yoshida H, Oishi K, Kimura H (2014) Molecular evolution of VP3, VP1, 3C(pro) and 3D(pol) coding regions in coxsackievirus group A type 24 variant isolates from acute hemorrhagic conjunctivitis in 2011 in Okinawa, Japan. Microbiol Immunol 58:227–238CrossRefPubMed
14.
Zurück zum Zitat Shukla D, Kumar A, Srivastava S, Dhole TN (2013) Molecular identification and phylogenetic study of coxsackievirus A24 variant isolated from an outbreak of acute hemorrhagic conjunctivitis in India in 2010. Arch Virol 158:679–684CrossRefPubMed Shukla D, Kumar A, Srivastava S, Dhole TN (2013) Molecular identification and phylogenetic study of coxsackievirus A24 variant isolated from an outbreak of acute hemorrhagic conjunctivitis in India in 2010. Arch Virol 158:679–684CrossRefPubMed
15.
Zurück zum Zitat Tavares FN, Campos RM, Burlandy FM, Fontella R, de Melo MM, Da CE, Da SE (2011) Molecular characterization and phylogenetic study of coxsackievirus A24v causing outbreaks of acute hemorrhagic conjunctivitis (AHC) in Brazil. PLoS One 6:e23206CrossRefPubMedPubMedCentral Tavares FN, Campos RM, Burlandy FM, Fontella R, de Melo MM, Da CE, Da SE (2011) Molecular characterization and phylogenetic study of coxsackievirus A24v causing outbreaks of acute hemorrhagic conjunctivitis (AHC) in Brazil. PLoS One 6:e23206CrossRefPubMedPubMedCentral
16.
Zurück zum Zitat Wu B, Qi X, Xu K, Ji H, Zhu Y, Tang F, Zhou M (2014) Genetic characteristics of the coxsackievirus A24 variant causing outbreaks of acute hemorrhagic conjunctivitis in Jiangsu, China, 2010. PLoS One 9:e86883CrossRefPubMedPubMedCentral Wu B, Qi X, Xu K, Ji H, Zhu Y, Tang F, Zhou M (2014) Genetic characteristics of the coxsackievirus A24 variant causing outbreaks of acute hemorrhagic conjunctivitis in Jiangsu, China, 2010. PLoS One 9:e86883CrossRefPubMedPubMedCentral
17.
Zurück zum Zitat Wu D, Ke CW, Mo YL, Sun LM, Li H, Chen QX, Zou LR, Fang L, Huang P, Zhen HY (2008) Multiple outbreaks of acute hemorrhagic conjunctivitis due to a variant of coxsackievirus A24: Guangdong, China, 2007. J Med Virol 80:1762–1768CrossRefPubMed Wu D, Ke CW, Mo YL, Sun LM, Li H, Chen QX, Zou LR, Fang L, Huang P, Zhen HY (2008) Multiple outbreaks of acute hemorrhagic conjunctivitis due to a variant of coxsackievirus A24: Guangdong, China, 2007. J Med Virol 80:1762–1768CrossRefPubMed
18.
Zurück zum Zitat Yan D, Zhu S, Zhang Y, Zhang J, Zhou Y, Xu W (2010) Outbreak of acute hemorrhagic conjunctivitis in Yunnan, People’s Republic of China, 2007. Virol J 7:138CrossRefPubMedPubMedCentral Yan D, Zhu S, Zhang Y, Zhang J, Zhou Y, Xu W (2010) Outbreak of acute hemorrhagic conjunctivitis in Yunnan, People’s Republic of China, 2007. Virol J 7:138CrossRefPubMedPubMedCentral
19.
Zurück zum Zitat Chaves SS, Lobo S, Kennett M, Black J (2001) Coxsackie virus A24 infection presenting as acute flaccid paralysis. Lancet 357:605CrossRefPubMed Chaves SS, Lobo S, Kennett M, Black J (2001) Coxsackie virus A24 infection presenting as acute flaccid paralysis. Lancet 357:605CrossRefPubMed
20.
Zurück zum Zitat Newcombe NG, Andersson P, Johansson ES, Au GG, Lindberg AM, Barry RD, Shafren DR (2003) Cellular receptor interactions of C-cluster human group A coxsackieviruses. J Gen Virol 84:3041–3050CrossRefPubMed Newcombe NG, Andersson P, Johansson ES, Au GG, Lindberg AM, Barry RD, Shafren DR (2003) Cellular receptor interactions of C-cluster human group A coxsackieviruses. J Gen Virol 84:3041–3050CrossRefPubMed
21.
Zurück zum Zitat Zocher G, Mistry N, Frank M, Hahnlein-Schick I, Ekstrom JO, Arnberg N, Stehle T (2014) A sialic acid binding site in a human picornavirus. PLoS Pathog 10:e1004401CrossRefPubMedPubMedCentral Zocher G, Mistry N, Frank M, Hahnlein-Schick I, Ekstrom JO, Arnberg N, Stehle T (2014) A sialic acid binding site in a human picornavirus. PLoS Pathog 10:e1004401CrossRefPubMedPubMedCentral
22.
Zurück zum Zitat Nilsson EC, Jamshidi F, Johansson SM, Oberste MS, Arnberg N (2008) Sialic acid is a cellular receptor for coxsackievirus A24 variant, an emerging virus with pandemic potential. J Virol 82:3061–3068CrossRefPubMedPubMedCentral Nilsson EC, Jamshidi F, Johansson SM, Oberste MS, Arnberg N (2008) Sialic acid is a cellular receptor for coxsackievirus A24 variant, an emerging virus with pandemic potential. J Virol 82:3061–3068CrossRefPubMedPubMedCentral
23.
Zurück zum Zitat Mistry N, Inoue H, Jamshidi F, Storm RJ, Oberste MS, Arnberg N (2011) Coxsackievirus A24 variant uses sialic acid-containing O-linked glycoconjugates as cellular receptors on human ocular cells. J Virol 85:11283–11290CrossRefPubMedPubMedCentral Mistry N, Inoue H, Jamshidi F, Storm RJ, Oberste MS, Arnberg N (2011) Coxsackievirus A24 variant uses sialic acid-containing O-linked glycoconjugates as cellular receptors on human ocular cells. J Virol 85:11283–11290CrossRefPubMedPubMedCentral
24.
Zurück zum Zitat Lukashev AN, Lashkevich VA, Ivanova OE, Koroleva GA, Hinkkanen AE, Ilonen J (2005) Recombination in circulating human enterovirus B: independent evolution of structural and non-structural genome regions. J Gen Virol 86:3281–3290CrossRefPubMed Lukashev AN, Lashkevich VA, Ivanova OE, Koroleva GA, Hinkkanen AE, Ilonen J (2005) Recombination in circulating human enterovirus B: independent evolution of structural and non-structural genome regions. J Gen Virol 86:3281–3290CrossRefPubMed
25.
Zurück zum Zitat Attoh J, Obodai E, Adiku T, Odoom JK (2014) Prevalence of human enteroviruses among apparently healthy nursery school children in Accra. Pan Afr Med J 18:66CrossRefPubMedPubMedCentral Attoh J, Obodai E, Adiku T, Odoom JK (2014) Prevalence of human enteroviruses among apparently healthy nursery school children in Accra. Pan Afr Med J 18:66CrossRefPubMedPubMedCentral
26.
Zurück zum Zitat Joffret ML, Jegouic S, Bessaud M, Balanant J, Tran C, Caro V, Holmblat B, Razafindratsimandresy R, Reynes JM, Rakoto-Andrianarivelo M, Delpeyroux F (2012) Common and diverse features of cocirculating type 2 and 3 recombinant vaccine-derived polioviruses isolated from patients with poliomyelitis and healthy children. J Infect Dis 205:1363–1373CrossRefPubMed Joffret ML, Jegouic S, Bessaud M, Balanant J, Tran C, Caro V, Holmblat B, Razafindratsimandresy R, Reynes JM, Rakoto-Andrianarivelo M, Delpeyroux F (2012) Common and diverse features of cocirculating type 2 and 3 recombinant vaccine-derived polioviruses isolated from patients with poliomyelitis and healthy children. J Infect Dis 205:1363–1373CrossRefPubMed
27.
Zurück zum Zitat Wang X, Xing M, Zhang C, Yang Y, Chi Y, Tang X, Zhang H, Xiong S, Yu L, Zhou D (2014) Neutralizing antibody responses to enterovirus and adenovirus in healthy adults in China. Emerg Microbes Infect 3:e30CrossRefPubMedPubMedCentral Wang X, Xing M, Zhang C, Yang Y, Chi Y, Tang X, Zhang H, Xiong S, Yu L, Zhou D (2014) Neutralizing antibody responses to enterovirus and adenovirus in healthy adults in China. Emerg Microbes Infect 3:e30CrossRefPubMedPubMedCentral
Metadaten
Titel
Complete genome analysis of coxsackievirus A24 isolated in Yunnan, China, in 2013
verfasst von
Yilin Zhao
Jiansheng Liu
Haihao Zhang
Chen Guo
Longhui Xia
Fang Yang
Huai Yang
Qinxing Yang
Zhaoqing Yang
Shaohui Ma
Publikationsdatum
03.03.2016
Verlag
Springer Vienna
Erschienen in
Archives of Virology / Ausgabe 6/2016
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-016-2792-0

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