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Archives of Virology

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03.07.2019 | Annotated Sequence Record

Complete genome sequence and analysis of a new lethal arterivirus, Trionyx sinensis hemorrhagic syndrome virus (TSHSV), amplified from an infected Chinese softshell turtle

verfasst von: Sunjian Lyu, Xuemei Yuan, Haiqi Zhang, Weida Shi, Xiaoying Hang, Li Liu, Zheng Cao, Yinglei Wu

Erschienen in: Archives of Virology | Ausgabe 10/2019

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Abstract

Trionyx sinensis hemorrhagic syndrome virus (TSHSV) is a newly discovered lethal arterivirus that causes serious disease in Trionyx sinensis in China. In this study, the complete genome sequence of TSHSV was determined by RACE cloning, and the functions of the predicted proteins were predicted. The complete genome of TSHSV was found to be 17,875 bp in length, and a 3’-end poly(A) tail was detected. Eight TSHSV hypothetical proteins (TSHSV-HPs) were predicted by gene model identification. TSHSV-HP2, 3 and 4 were associated with replicase activity, since papain-like protease (PLPs), serine-type endopeptidase, P-loop-containing nucleoside triphosphate hydrolase, and EndoU-like endoribonuclease motifs were detected. Phylogenetic analysis showed that TSHSV clusters with an arterivirus from a Chinese broad-headed pond turtle.

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Titel: Complete genome sequence and analysis of a new lethal arterivirus, Trionyx sinensis hemorrhagic syndrome virus (TSHSV), amplified from an infected Chinese softshell turtle
verfasst von: Sunjian Lyu
Xuemei Yuan
Haiqi Zhang
Weida Shi
Xiaoying Hang
Li Liu
Zheng Cao
Yinglei Wu
Publikationsdatum: 03.07.2019
Verlag: Springer Vienna
Erschienen in: Archives of Virology / Ausgabe 10/2019
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-019-04324-8

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Complete genome sequence and analysis of a new lethal arterivirus, Trionyx sinensis hemorrhagic syndrome virus (TSHSV), amplified from an infected Chinese softshell turtle

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