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01.12.2014 | Review | Ausgabe 1/2014 Open Access

Clinical and Translational Allergy 1/2014

Component resolved diagnosis: when should it be used?

Zeitschrift:
Clinical and Translational Allergy > Ausgabe 1/2014
Autoren:
Olga Luengo, Victòria Cardona
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​2045-7022-4-28) contains supplementary material, which is available to authorized users.

Competing interests

The Allergy Research Group, to which OL and VC belong, receives research funds from Thermo Fischer Scientific, Spain.

Author’s contributions

All authors have equally collaborated in the design and drafting of this review. All authors read and approved the final manuscript.

Abstract

The knowledge on molecular allergy diagnosis is continuously evolving. It is now time for the clinician to integrate this knowledge and use it when needed to improve the accuracy of diagnosis and thus provide more precise therapeutic and avoidance measures. This review does not intend to comprehensively analyze all the available allergen molecules, but to provide some practical clues on use and interpretation of molecular allergy diagnosis. The potential role of component resolved diagnosis in circumstances such as the indication of allergen immunotherapy, pollen polysensitization, food allergy, latex allergy or anaphylaxis, is assessed. Interpreting the information provided by molecular allergy diagnosis needs a structured approach. It is necessary to evaluate single positivities and negativities, but also to appraise “the big picture” with perspective.
Zusatzmaterial
Authors’ original file for figure 1
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Authors’ original file for figure 2
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Authors’ original file for figure 3
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Authors’ original file for figure 4
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Authors’ original file for figure 5
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Literatur
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