Preface 2009
Contents
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Figure 2 Survival of patients treated with EMR/ESD according to the pathological depth of tumor invasion (pT)×
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Figure 7 Survival of patients who underwent esophagectomy according to clinical stage (JES TNM 10th)×
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Figure 8 Survival of patients who underwent esophagectomy according to clinical stage (UICC TNM 6th)×
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Figure 9 Survival of patients who underwent esophagectomy according to the depth of tumor invasion (JES 10th: pT)×
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Figure 10 Survival of patients who underwent esophagectomy according to the depth of tumor invasion (UICC TNM 6th: pT)×
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Figure 11 Survival of patients who underwent esophagectomy according to lymph node metastasis (JES 10th: pN)×
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Figure 12 Survival of patients who underwent esophagectomy according to lymph node metastasis (UICC TNM 6th: pN)×
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Figure 13 Survival of patients who underwent esophagectomy according to number of metastatic nodes×
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Figure 14 Survival of patients who underwent esophagectomy according to pathological stage (JES 10th)×
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Figure 15 Survival of patients who underwent esophagectomy according to pathological stage (UICC TNM 6th)×
I. Clinical factors of esophageal cancer patients treated in 2009
Institution-registered cases in 2009
Institutions |
---|
Aichi Cancer Center |
Aizawa Hospital |
Akita University Hospital |
Aomori Municipal Hospital |
Aomori Prefectural Central Hospital |
Arao Municipal Hospital |
Asahikawa Medical College Hospital |
Chiba Cancer Center |
Chiba Medical Center |
Chiba University Hospital |
Chibaken Saiseikai Narashino Hospital |
Dokkyo Medical University Hospital |
Ehime University Hospital |
Foundation for Detection of Early Gastric Carcinoma |
Fuchu Hospital |
Fujioka General Hospital |
Fujisawa Shounandai Hospital |
Fujita Health University |
Fukui Prefectural Hospital |
Fukui University Hospital |
Fukuoka Dental College and Dental Hospital |
Fukuoka Saiseikai General Hospital? |
Fukuoka University Hospital |
Fukuoka Wajiro Hospital |
Fukushima Medical University Hospital |
Fukuyama City Hopital |
Gifu Prefectural General Medical Center |
Gifu University Hospital |
Gunma Central General Hospital |
Gunma Prefectural Cancer Center |
Gunma University Hospital |
Gunmaken Saiseikai Maebashi Hospital |
Hachinohe City Hospital |
Hakodate Goryokaku Hospital |
Hakodate National Hospital |
Hamamatsu University School of Medicine, University Hospital |
Handa City Hospital |
Hannan Chuo Hospital |
Heartlife Hospital |
Higashiosaka City General Hospital |
Hino Memorial Hospital |
Hiratsuka City Hospital |
Hiratsuka Kyosai Hospital |
Hirosaki University Hospital |
Hiroshima City Asa Hospital |
Hiroshima University Research Institute for Radiation Biology Medicine |
Hitachi General Hospital |
Hofu Institute of Gastroenterology |
Hokkaido Kin-Ikyo Chuo Hospital |
Hokkaido University Hospital |
Hyogo Cancer Center |
Hyogo College of Medicine |
Hyogo Prefectural Nishinomiya Hospital |
Ibaraki Prefectural Central Hospital |
Iizuka Hospital |
Imazu Surgical Clinic |
Inazawa City Hospital |
Internatinal University of Health and Welfare Hospital |
Isehara Kyodo Hospital |
Ishikawa Prefectural Central Hospital |
Iwakuni Medical Center |
Iwate Medical University Hospital |
Iwate Prefectural Chubu Hospital |
Iwate Prefectural Isawa Hospital |
Japanese Red Cross Fukui Hospital |
Japanese Red Cross Ishinomaki Hospital |
Japanese Red Cross Kyoto Daini Hospital? |
Japanese Red Cross Maebashi Hospital |
Japanese Red Cross Nagaoka Hospital |
Japanese Red Cross Narita Hospital |
Japanese Red Cross Nasu Hospital |
Jichi Medical University Hospital |
Juntendo University Hospital |
Juntendo University Shizuoka Hospital |
Junwakai Memorial Hospital |
Kagawa Rosai Hospital |
Kagawa University Hospital |
Kagoshima Kenritsu Satsunan Hospital |
Kagoshima University Hospital |
Kameda General Hospital |
Kanagawa Cancer Center |
Kanazawa Medical University Hospital |
Kanazawa University Hospital |
Kansai Medical University Hirakata Hospital |
Kansai Rosai Hospital |
Kashiwa Kousei General Hospital |
Kawakita General Hospital |
Kawasaki Medical School Hospital |
Kawasaki Medical School Kawasaki Hospital |
Kawasaki Municipal Hospital |
Kawasaki Municipal Ida Hospital |
Keio University Hospital |
Keiyukai Sapporo Hospital |
Kikuna Memorial Hospital |
Kinki Central Hospital |
Kinki University Hospital |
Kiryu Kosei General Hospital |
Kishiwada City Hospital |
Kitaakita Municipal Hospital |
Kitakyushu Municipal Medical Center |
Kitano Hospital |
Kitasato University Hospital |
Kobe City Medical Center General Hospital |
Kobe University Hospital |
Kochi University Hospital |
Kokura Memorial Hospital |
Kumamoto City Hospital |
Kumamoto University Hospital |
Kurashiki Central Hospital |
Kurume General Hospital |
Kurume University Hospital |
Kuwana West Medical Center |
Kyoto University Hospital |
Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers |
Kyushu University Beppu Hospital |
Kyushu University Hospital |
Kyushu Medical Center |
Machida Municipal Hospital |
Matsuda Hospital |
Matsushita Memorial Hospital |
Matsuyama Red Cross Hospital |
Mie University Hospital |
Mino City Hospital |
Mito Red Cross Hospital |
Mitsui Memorial Hospital |
Miyazaki Konan Hospital |
Murakami General Hospital |
Musashimurayama Hospital |
Musashino Red Cross Hospital |
Nagahama City Hospital |
Nagano Red Cross Hospital |
Nagaoka Chuo General Hospital |
Nagasaki University Hospital |
Nagayoshi General Hospital |
Nagoya City University Hospital |
Nagoya City West Medical Center |
Nagoya Daiichi Red Cross Hospital |
Nagoya University Hospital |
Nara Hospital Kinki University Faculty of Medicine |
Nara Medical University Hospital |
National Cancer Center Hospital |
National Cancer Center Hospital East |
National Center for Global Health and Medicine |
National Defense Medical College Hospital |
National Hospital Organization Beppu Medical Center |
National Hospital Organization Chiba-East-Hospital |
National Hospital Organization Fukuoka-higashi Medical Center |
National Hospital Organization Kure Medical Center |
National Hospital Organization Kyoto Medical Center |
National Hospital Organization Kyushu Cancer Center |
National Hospital Organization Matsumoto National Hospital |
National Hospital Organization Nagasaki Medical Center. |
National Hospital Organization Nagoya Medical Center |
National Hospital Organization Osaka National Hospital |
National Hospital Organization Tokyo Medical Center |
Niigata Cancer Center Hospital |
Niigata City General Hospital |
Niigata Prefectural Shibata Hospital |
Niigata University Medical and Dental Hospital |
Nikko Memorial Hospital |
Nippon Medical School Chiba Hokusoh Hospital |
Nippon Medical School Hospital |
Nippon Medical School Musashi Kosugi Hospital |
Nippon Medical School Tama Nagayama Hospital |
Nishi-Kobe Medical Center |
Nishinomiya Municipal Central Hospital |
Numazu City Hospital |
Obihiro Kousei General Hospital |
Ohta General Hospital Foundation Ohta Nishinouchi Hospital |
Oita Red Cross Hospital |
Oita University Hospital |
Okayama Saiseikai General Hospital |
Okayama University Hospital |
Onomichi Municipal Hospital |
Osaka City General Hospital |
Osaka City University Hospital |
Osaka Hospital of Japan Seafarers relief Association |
Osaka Medical Center for Cancer and Cardiovascular Diseases |
Osaka Medical College Hospital |
Osaka Police Hospital |
Osaka Prefectural Hospital Organization Osaka General Medical Center |
Osaka Red Cross Hospital |
Osaka University Hospital |
Otsu Municipal Hospital |
Otsu Red Cross Hospital |
Rakusei Hospital |
Ryukyu University Hospital |
Saga University Hospital |
Saga-ken Medical Center Koseikan |
Saiseikai Fukushima General Hospital |
Saiseikai Hiroshima Hospital |
Saiseikai Kyoto Hospital |
Saiseikai Utsunomiya Hospital |
Saitama City Hospital |
Saitama Medical Center Jichi Medical University |
Saitama Medical University Hospital |
Saitama Medical University Saitama International Medical Center |
Saitama Medical University Saitama Medical Center |
Saitama Medical Center |
Sakai City Medical Center |
Saku Central Hospital |
Sanin Rosai Hospital |
Sano Kousei General Hospital |
Sendai City Hospital |
Shiga Medical Center for Adults |
Shiga University of Medical Science Hospital |
Shikoku Cancer Center |
Shimada Hospital |
Shimane University Hospital |
Shimizu Welfare Hospital |
Shinshu University Hospital |
Shizuoka Cancer Center |
Shizuoka City Shizuoka Hospital |
Shizuoka General Hospital |
Showa University Hospital |
Showa University Northern Yokohama Hospital |
Showa University Koto-Toyosu Hospital |
Social Insurance Omuta Tenryo Hospital |
Social Insurance Tagawa Hospital |
Yokohama Chuo Hospital |
Sonoda Daiichi Hospital |
St. Marianna University School of Medical Hospital |
St. Luke’s International Hospital |
Sugita Genpaku Memorial Obama Municipal Hospital |
Suita Municipal Hospital |
Takasago Municipal Hospital |
Takatsuki Red Cross Hospital |
Teikyo University Hospital |
Tenri Hospital |
The Cancer Institute Hospital of JFCR |
The Jikei University Hospital |
The Research Center Hospital for Charged Particle Therapy of NIRS |
Toho University Omori Medical Center |
Toho University Sakura Medical Center |
Tohoku Kosai Hospital |
Tohoku University Hospital |
Tokai University Hachioji Hospital |
Tokai University Hospital |
Tokai University Tokyo Hospital |
Tokushima Municipal Hospital |
Tokushima Red Cross Hospital |
Tokushima University Hospital |
Tokyo Dental College Ichikawa General Hospital |
Tokyo Medical and Dental University Hospital |
Tokyo Medical University Hospital |
Tokyo Medical University Ibaraki Medical Center |
Tokyo Metropolitan Cancer and Infectious Center Komagome Hospital |
Tokyo Metropolitan Health and Medical Corporation Toshima Hospital |
Tokyo University Hospital |
Tokyo Women’s Medical University Hospital |
Tokyo Women’s Medical University Medical Center East |
Tonan Hospital |
Tone Chuou Hospital |
Tottori Prefectural Central Hospital |
Tottori University Hospital |
Toyama Prefectural Central Hospital |
Toyama University Hospital |
Tsuchiura Kyodo Hospital |
Tsukuba University Hospital |
Tsuruoka Municipal Shonai Hospital |
“University Hospital, Kyoto Prefectural University of Medicine” |
University of Miyazaki Hospital |
Wakayama Medical University Hospital |
Yamagata Prefectural and Sakata Municipal Hospital Organization |
Yamagata Prefectural Central Hospital |
Yamagata Prefectural Shinjo Hospital |
Yamagata University Hospital |
Yamaguchi University Hospital |
Yamaguchi-ken Saiseikai Shimonoseki General Hospital |
Yamanashi Prefectural Central Hospital |
Yamanashi University Hospital |
Yao Municipal Hospital |
Yokohama City Municipal Hospital |
Yokohama City University Hospital |
Yokohama City University Medical Center |
Yuri General Hospital |
Patient Background
Age | Male | Female | Unknown | Cases (%) |
---|---|---|---|---|
~29 | 6 | 1 | 0 | 7 (0.1 %) |
30–39 | 12 | 6 | 0 | 18 (0.3 %) |
40–49 | 121 | 34 | 0 | 155 (2.5 %) |
50–59 | 946 | 173 | 1 | 1120 (17.9 %) |
60–69 | 2332 | 354 | 0 | 2686 (42.9 %) |
70–79 | 1575 | 270 | 1 | 1846 (29.5 %) |
80–89 | 303 | 75 | 0 | 378 (6.0 %) |
90~ | 16 | 3 | 0 | 19 (0.3 %) |
Unknown | 27 | 4 | 0 | 31 (0.5 %) |
Total | 5338 | 920 | 2 | 6260 (100 %) |
Treatments | Cases (%) |
---|---|
Surgery | 3943 (63.0 %) |
Esophagectomy | 3844 (61.8 %) |
Palliative | 99 (1.2 %) |
Chemotherapy/radiotherapy | 1383 (22.1 %) |
Endoscopic treatment | 932 (14.9 %) |
Others | 2 (0.0 %) |
Total | 6260 (100 %) |
Location of tumor | Endoscopic treatment (%) | Chemotherapy and/or radiotherapy (%) | Palliative surgery (%) | Esophagectomy (%) | Other (%) | Total (%) |
---|---|---|---|---|---|---|
Cervical | 18 (1.9 %) | 112 (8.1 %) | 9 (9.1 %) | 137 (3.6 %) | 0 | 276 (4.4 %) |
Upper thoracic | 105 (11.3 %) | 184 (13.3 %) | 19 (19.2 %) | 437 (11.4 %) | 0 | 745 (11.9 %) |
Middle thoracic | 511 (54.8 %) | 665 (48.1 %) | 50 (50.5 %) | 1778 (46.3 %) | 1 (50.0 %) | 3005 (48.0 %) |
Lower thoracic | 243 (26.1 %) | 325 (23.5 %) | 18 (18.2 %) | 1147 (29.8 %) | 0 | 1733 (27.7 %) |
E > G | 40 (4.3 %) | 38 (2.7 %) | 2 (2.0 %) | 245 (6.4 %) | 0 | 325 (5.2 %) |
E = G | 5 (0.5 %) | 6 (0.4 %) | 0 | 41 (1.1 %) | 0 | 52 (0.8 %) |
G > E | 0 | 2 (0.1 %) | 0 | 34 (0.9 %) | 0 | 36 (0.6 %) |
Unknown | 10 (1.1 %) | 51 (3.7 %) | 1 (1.0 %) | 25 (0.7 %) | 1 (50.0 %) | 88 (1.4 %) |
Total | 932 (100 %) | 1383 (100 %) | 99 (100 %) | 3844 (100 %) | 2 (100 %) | 6260 (100 %) |
Histologic types | Cases (%) |
---|---|
Squamous cell carcinoma | 5665 (90.5 %) |
Squamous cell carcinoma | 3827 (61.1 %) |
Well differentiated | 354 (5.7 %) |
Moderately differentiated | 1140 (18.2 %) |
Poorly differentiated | 344 (5.5 %) |
Adenocarcinoma | 296 (4.7 %) |
Adenosquamous carcinoma | 13 (0.2 %) |
Mucoepidermoid carcinoma | 1 (0.0 %) |
Basaloid carcinoma | 22 (0.4 %) |
Neuroendocrine cell carcinoma | 14 (0.2 %) |
Undifferentiated carcinoma | 10 (0.2 %) |
Malignant melanoma | 7 (0.1 %) |
Carcinosarcoma | 17 (0.3 %) |
Other tumors | 28 (0.4 %) |
Unknown | 187 (3.0 %) |
Total | 6260 (100 %) |
cT | Cases (%) |
---|---|
cTX | 29 (0.5 %) |
cT0 | 11 (0.2 %) |
cTis | 157 (2.5 %) |
cT1 | 359 (5.7 %) |
cT1a | 650 (10.4 %) |
cT1b | 1134 (18.1 %) |
cT2 | 868 (13.9 %) |
cT3 | 2252 (36.0 %) |
cT4 | 701 (11.2 %) |
Unknown | 99 (1.6 %) |
Total | 6260 (100 %) |
cN | Cases (%) |
---|---|
cNX | 72 (1.2 %) |
cN0 | 2920 (46.6 %) |
cN1 | 3157 (50.4 %) |
Unknown | 111 (1.8 %) |
Total | 6260 (100 %) |
cM | Cases (%) |
---|---|
cMX | 57 (0.9 %) |
cM0 | 5295 (84.6 %) |
cM1 | 223 (3.6 %) |
cM1a | 141 (2.3 %) |
cM1b | 466 (7.4 %) |
Total | 6260 (100 %) |
Location of tumor | Endoscopic treatment (%) | Chemotherapy and/or radiotherapy (%) | Palliative surgery (%) | Esophagectomy (%) | Other (%) | Total (%) |
---|---|---|---|---|---|---|
0 | 131 (14.1 %) | 6 (0.4 %) | 1 (1.0 %) | 13 (0.3 %) | 0 | 151 (2.4 %) |
I | 658 (70.6 %) | 152 (11.0 %) | 2 (2.0 %) | 964 (25.1 %) | 0 | 1776 (28.4 %) |
IIA | 6 (0.6 %) | 125 (9.0 %) | 7 (7.1 %) | 717 (18.7 %) | 0 | 855 (13.7 %) |
IIB | 7 (0.8 %) | 98 (7.1 %) | 2 (2.0 %) | 555 (14.4 %) | 0 | 662 (10.6 %) |
III | 29 (3.1 %) | 452 (32.7 %) | 62 (62.6 %) | 1243 (32.3 %) | 1 (50.0 %) | 1787 (28.5 %) |
IV | 10 (1.1 %) | 139 (10.1 %) | 7 (7.1 %) | 44 (1.1 %) | 0 | 200 (3.2 %) |
IVA | 5 (0.5 %) | 53 (3.8 %) | 1 (1.0 %) | 81 (2.1 %) | 0 | 140 (2.2 %) |
IVB | 18 (1.9 %) | 265 (19.2 %) | 12 (12.1 %) | 156 (4.1 %) | 0 | 451 (7.2 %) |
Unknown | 68 (7.3 %) | 93 (6.7 %) | 5 (5.1 %) | 71 (1.8 %) | 1 (50.0 %) | 238 (3.8 %) |
Total | 932 (100 %) | 1383 (100 %) | 99 (100 %) | 3844 (100 %) | 2 (100 %) | 6260 (100 %) |
II. Results of endoscopically treated patients in 2009
Treatment details | Cases (%) |
---|---|
EMR | 201 (21.6 %) |
EMR + ESD | 11 (1.2 %) |
EMR + YAG laser | 7 (0.8 %) |
ESD | 607 (65.1 %) |
ESD + other treatment | 7 (0.8 %) |
PDT | 2 (0.2 %) |
PDT + YAG laser | 2 (0.2 %) |
YAG laser | 10 (1.1 %) |
Esophageal stenting | 70 (7.5 %) |
Esophageal stenting + tracheal stenting | 2 (0.2 %) |
Tracheal stenting | 4 (0.4 %) |
Others | 5 (0.5 %) |
Unknown | 4 (0.4 %) |
Total | 753 (100 %) |
Complications of EMR/ESD | Cases (%) |
---|---|
None | 766 (91.8 %) |
Perforation | 16 (1.9 %) |
Bleeding | 2 (0.2 %) |
Mediastinitis | 0 |
Stenosis | 42 (5.0 %) |
Others | 7 (0.8 %) |
Unknown | 1 (0.1 %) |
Total | 834 (100 %) |
Pathological depth of tumor invasion | Cases (%) |
---|---|
pTX | 1 (0.1 %) |
pT0 | 5 (0.6 %) |
pTis | 166 (19.9 %) |
pT1a | 507 (60.9 %) |
pT1b | 86 (10.3 %) |
pT2 | 0 |
Unknown | 68 (8.2 %) |
Total | 833 (100 %) |
III. Results in patients treated with chemotherapy and/or radiotherapy in 2009
Dose of radiation (Gy) | Definitive | Palliative (%) | Recurrence (%) | Others (%) | Unknown (%) | Total (%) | |
---|---|---|---|---|---|---|---|
Radiation alone (%) | With chemotherapy (%) | ||||||
–29 | 5 (4.1 %) | 18 (2.3 %) | 23 (11.0 %) | 2 (6.1 %) | 0 | 1 (5.6 %) | 49 (4.1 %) |
30–39 | 1 (0.8 %) | 15 (1.9 %) | 25 (11.9 %) | 3 (9.1 %) | 1 (7.1 %) | 0 | 45 (3.8 %) |
40–49 | 11 (8.9 %) | 40 (5.1 %) | 31 (14.8 %) | 9 (27.3 %) | 8 (57.1 %) | 1 (5.6 %) | 100 (8.4 %) |
50–59 | 24 (19.5 %) | 199 (25.3 %) | 47 (22.4 %) | 8 (24.2 %) | 2 (14.3 %) | 1 (5.6 %) | 281 (23.7 %) |
60–69 | 74 (60.2 %) | 493 (62.6 %) | 81 (38.6 %) | 9 (27.3 %) | 2 (14.3 %) | 15 (83.3 %) | 674 (56.8 %) |
70- | 6 (7.2 %) | 8 (2.1 %) | 2 (0.0 %) | 0 | 0 | 0 | 16 (2.2 %) |
Unknown | 2 (1.6 %) | 15 (1.9 %) | 1 (0.5 %) | 2 (6.1 %) | 1 (7.1 %) | 0 | 21 (1.8 %) |
Total | 123 (100 %) | 788 (100 %) | 210 (100 %) | 33 (100 %) | 14 (100 %) | 18 (100 %) | 1186 (100 %) |
Median (min–max) | 60.0 (6.0–120.0) | 60.0 (2.0–124.0) | 54.0 (2.0–95.4) | 50.0 (20.0–66.0) | 40.0 (36.0–60.0) | 60.0 (2.0–61.2) | 60.0 (2.0–124.0) |
Dose of radiation (Gy) | Preoperative radiation (%) | Postoperative radiation (%) |
---|---|---|
–29 | 3 (1.4 %) | 1 (1.4 %) |
30–39 | 54 (24.4 %) | 2 (2.7 %) |
40–49 | 132 (59.7 %) | 21 (28.4 %) |
50–59 | 9 (4.1 %) | 18 (24.3 %) |
60–69 | 15 (6.8 %) | 27 (36.5 %) |
70- | 0 | 0 (1.1 %) |
Unknown | 8 (3.6 %) | 5 (6.8 %) |
Total | 221 (100 %) | 74 (100 %) |
Median (min–max) | 40.0 (15.0–66.0) | 50.4 (4.0–64.0) |
IV. Results in patients who underwent esophagectomy in 2009
Treatments | Cases (%) |
---|---|
Esophagectomy | 1630 (42.4 %) |
Esophagectomy + radiotherapy | 65 (1.7 %) |
Esophagectomy + chemoradiotherapy | 655 (17.0 %) |
Esophagectomy + chemoradiotherapy + endoscopic treatment | 16 (0.4 %) |
Esophagectomy + chemoradiotherapy + other treatment | 2 (0.1 %) |
Esophagectomy + radiotherapy + endoscopic treatment | 3 (0.1 %) |
Esophagectomy + radiotherapy + other treatment | 1 (0.0 %) |
Esophagectomy + chemotherapy | 1385 (36.0 %) |
Esophagectomy + chemotherapy + endoscopic treatment | 8 (0.2 %) |
Esophagectomy + chemotherapy + other treatment | 2 (0.1 %) |
Esophagectomy + endoscopic treatment | 77 (2.0 %) |
Total | 3844 (100 %) |
Locations | Cases (%) |
---|---|
Cervical | 137 (3.6 %) |
Upper thoracic | 437 (11.4 %) |
Middle thoracic | 1778 (46.3 %) |
Lower thoracic | 1147 (29.8 %) |
E > G | 245 (6.4 %) |
E = G | 41 (1.1 %) |
G > E | 34 (0.9 %) |
Unknown | 25 (0.7 %) |
Total lesions | 3844 (100 %) |
Approaches | Cases (%) |
---|---|
Cervical approach | 132 (3.4 %) |
Right thoracotomy | 3239 (84.3 %) |
Left thoracotomy | 66 (1.7 %) |
Left thoracoabdominal approach | 49 (1.3 %) |
Laparotomy | 148 (3.9 %) |
Transhiatal thoracic esophagectomy | 52 (1.4 %) |
Transhiatal lower esophagectomy | 92 (2.4 %) |
Sternotomy | 2 (0.1 %) |
Others | 32 (0.8 %) |
Unknown | 32 (0.8 %) |
Total | 3844 (100 %) |
Video-assisted surgery | Cases (%) |
---|---|
None | 2549 (66.3 %) |
Thoracoscopy | 554 (14.4 %) |
Laparoscopy | 124 (3.2 %) |
Thoracoscopy + laparoscopy | 388 (10.1 %) |
Mediastinoscopy | 26 (0.7 %) |
Thoracoscopy + laparoscopy + mediastinoscopy | 4 (0.1 %) |
Thoracoscopy + other | 11 (0.3 %) |
Laparoscopy + mediastinoscopy | 5 (0.1 %) |
Others | 17 (0.4 %) |
Unknown | 166 (4.3 %) |
Total | 3844 (100 %) |
Field of lymphadenectomy | Cervical | Upper thoracic | Middle thoracic | Lower thoracic | E > G | E = G | G > E | Unknown | Total |
---|---|---|---|---|---|---|---|---|---|
None | 9 (6.6 %) | 21 (4.8 %) | 76 (4.3 %) | 39 (3.4 %) | 5 (2.0 %) | 4 (9.8 %) | 1 (2.9 %) | 6 (75.0 %) | 161 (4.2 %) |
C | 51 (37.2 %) | 5 (1.1 %) | 13 (0.7 %) | 3 (0.3 %) | 0 (0.0 %) | 0 | 0 | 1 (12.5 %) | 73 (1.9 %) |
C + UM | 20 (14.6 %) | 5 (1.1 %) | 0 | 0 | 0 | 0 | 0 | 0 | 25 (0.7 %) |
C + UM + MLM | 7 (5.1 %) | 9 (2.1 %) | 45 (2.5 %) | 18 (1.6 %) | 2 (0.8 %) | 0 | 0 | 0 (0.0 %) | 81 (2.1 %) |
C + UM + MLM + A | 35 (25.5 %) | 286 (65.4 %) | 935 (52.6 %) | 435 (37.9 %) | 29 (11.8 %) | 3 (7.3 %) | 1 (2.9 %) | 8 (100.0 %) | 1732 (45.1 %) |
C + UM + MLM + A + other | 2 (1.5 %) | 4 (0.9 %) | 0 | 1 (0.1 %) | 0 | 0 | 0 | 0 | 7 (0.2 %) |
C + UM + A | 0 (0.0 %) | 1 (0.2 %) | 1 (0.1 %) | 0 | 0 | 0 | 0 | 0 | 2 (0.1 %) |
C + MLM + A | 0 | 2 (0.5 %) | 4 (0.2 %) | 4 (0.3 %) | 0 | 0 | 0 | 0 | 10 (0.3 %) |
C + A | 5 (3.6 %) | 1 (0.2 %) | 3 (0.2 %) | 3 (0.3 %) | 0 | 0 | 0 | 1 (12.5 %) | 13 (0.3 %) |
UM | 0 | 5 (1.1 %) | 4 (0.2 %) | 5 (0.4 %) | 0 | 0 | 0 | 0 | 14 (0.4 %) |
UM + MLM | 2 (1.5 %) | 10 (2.3 %) | 17 (1.0 %) | 13 (1.1 %) | 2 (0.8 %) | 0 | 0 | 1 (12.5 %) | 45 (1.2 %) |
UM + MLM + A | 0 | 64 (14.6 %) | 584 (32.8 %) | 485 (42.3 %) | 81 (33.1 %) | 9 (22.0 %) | 5 (14.7 %) | 2 (25.0 %) | 1230 (32.0 %) |
UM + MLM + A + other | 0 | 0 (0.0 %) | 1 (0.1 %) | 0 | 0 | 0 | 0 | 0 | 1 (0.0 %) |
UM + A | 0 | 1 (0.2 %) | 3 (0.2 %) | 3 (0.3 %) | 0 | 0 | 0 | 0 | 7 (0.2 %) |
MLM | 0 | 3 (0.7 %) | 13 (0.7 %) | 5 (0.4 %) | 3 (1.2 %) | 0 | 0 | 0 (0.0 %) | 24 (0.6 %) |
MLM + A | 1 (0.7 %) | 12 (2.7 %) | 50 (2.8 %) | 104 (9.1 %) | 91 (37.1 %) | 16 (39.0 %) | 9 (26.5 %) | 3 (37.5 %) | 286 (7.4 %) |
A | 1 (0.7 %) | 5 (1.1 %) | 20 (1.1 %) | 24 (2.1 %) | 30 (12.2 %) | 9 (22.0 %) | 18 (52.9 %) | 0 | 107 (2.8 %) |
Unknown | 4 (2.9 %) | 3 (0.7 %) | 9 (0.5 %) | 5 (0.4 %) | 2 (0.8 %) | 0 | 0 | 3 (37.5 %) | 26 (0.7 %) |
Total | 137 (100 %) | 437 (100 %) | 1778 (100 %) | 1147 (100 %) | 245 (100 %) | 41 (100 %) | 34 (100 %) | 25 (100 %) | 3844 (100 %) |
Reconstruction route | Cases (%) |
---|---|
None | 48 (1.2 %) |
Subcutaneous | 323 (8.4 %) |
Retrosternal | 1422 (37.0 %) |
Intrathoracic | 446 (11.6 %) |
Posterior mediastinal | 1491 (38.8 %) |
Cervical | 49 (1.3 %) |
Others | 36 (0.9 %) |
Unknown | 29 (0.8 %) |
Total | 3844 (100 %) |
Organs used for reconstruction | Cases (%) |
---|---|
None | 51 (1.3 %) |
Whole stomach | 102 (2.6 %) |
Gastric tube | 3234 (81.6 %) |
Jejunum | 213 (5.4 %) |
Free jejunum | 88 (2.2 %) |
Colon | 153 (3.9 %) |
Free colon | 12 (0.3 %) |
Skin graft | 0 (0.0 %) |
Others | 93 (2.3 %) |
Unknown | 18 (0.5 %) |
Total organs | 3964 (100 %) |
Total cases | 3844 |
Histological classification | Cases (%) |
---|---|
Squamous cell carcinoma | 3300 (86.7 %) |
Squamous cell carcinoma | 685 (18.0 %) |
Well differentiated | 653 (17.2 %) |
Moderately differentiated | 1521 (40.0 %) |
Poorly differentiated | 441 (11.6 %) |
Adenocarcinoma | 222 (5.8 %) |
Adenosquamous cell carcinoma | 35 (0.9 %) |
Adenoid cystic carcinoma | 1 (0.0 %) |
Basaloid carcinoma | 56 (1.5 %) |
Neuroendocrine cell carcinoma | 17 (0.4 %) |
Undifferentiated carcinoma | 10 (0.3 %) |
Other carcinoma | 9 (0.2 %) |
Carcinosarcoma | 21 (0.6 %) |
Malignant melanoma | 11 (0.3 %) |
GIST | 1 (0.0 %) |
Other | 46 (1.2 %) |
Unknown | 78 (2.0 %) |
Total | 3807 (100 %) |
pT category | Cases (%) |
---|---|
pTX | 24 (0.6 %) |
pT0 | 94 (2.4 %) |
pTis | 29 (0.8 %) |
pT1a | 422 (11.0 %) |
pT1b | 1065 (27.7 %) |
pT2 | 454 (11.8 %) |
pT3 | 1518 (39.5 %) |
pT4 | 127 (3.3 %) |
pT4a | 27 (0.7 %) |
pT4b | 30 (0.8 %) |
Unknown | 54 (1.4 %) |
Total | 3844 (100 %) |
Lymph node metastasis | Cases (%) |
---|---|
pN0 | 2270 (59.1 %) |
pN1 | 492 (12.8 %) |
pN2 | 584 (15.2 %) |
pN3 | 225 (5.9 %) |
pN4 | 185 (4.8 %) |
Unknown | 88 (2.3 %) |
Total | 3844 (100 %) |
Numbers of lymph node metastasis | Cases (%) |
---|---|
0 | 1779 (46.3 %) |
1-2 | 985 (25.6 %) |
3-6 | 640 (16.6 %) |
7- | 376 (9.8 %) |
Unknown | 64 (1.7 %) |
Total | 3844 (100 %) |
Distant metastasis | Cases (%) |
---|---|
pMX | 53 (1.4 %) |
pM0 | 3733 (97.1 %) |
pM1 | 58 (1.5 %) |
Total | 3844 (100 %) |
Residual tumor | Cases (%) |
---|---|
RX | 156 (4.1 %) |
R0 | 3345 (87.0 %) |
R1 | 187 (4.9 %) |
R2 | 156 (4.1 %) |
Total | 3844 (100 %) |
Cause of death | Cases (%) |
---|---|
Death due to recurrence | 1139 (72.8 %) |
Death due to other cancer | 65 (4.2 %) |
Death due to other disease (rec +) | 44 (2.8 %) |
Death due to other disease (rec-) | 179 (11.4 %) |
Death due to other disease (rec?) | 7 (0.4 %) |
Operative death* | 39 (2.5 %) |
Postoperative hospital death** | 40 (2.6 %) |
Unknown | 52 (3.3 %) |
Total of death cases | 1565 (100 %) |