This is one of the few studies of Gartner’s cysts with a series of consecutive cases followed over a long period of time who were exclusively subject to clinical observation. Most of the case series presented in the literature typically present patients who were treated surgically [
8]. The follow-up of these patients ranged from 2 to 17 years. In these four cases the location of the cysts was the right wall of the vagina. Gartner’s cysts are typically small with an average diameter of 2 cm. However, these cysts can increase in size and be confused with other structures, such as cystocele and uterine prolapse [
6]. In fact, in this series, the size ranged from 1.5 to 4.2 cm. In all cases, the diagnosis was made incidentally during routine pelvic examination and most lesions were asymptomatic. Only one of the four women had urethral stricture with a history of recurrent UTI, but this condition did not have any relation with the presence of the cyst (
Case 3). Transvaginal ultrasound was the test of choice for diagnostic confirmation (Fig.
3b). The investigation of the characteristics of these lesions can be made with urinary tract imaging tests, such as ultrasound and MRI. Intravenous pyelography and computed tomography are additional examinations that may be requested [
1]. Treatment depends on the symptoms and desire of the patient. In the cases presented in this study, the women were asymptomatic and chose to be observed clinically. In this situation, surgery is not typically performed because this type of surgery can be complex and is not recommended unless the patient has severe symptoms [
9]. When a patient is symptomatic, the initial procedure can involve cyst drainage, injection, or aspiration, and intra-cystic tetracycline [
10]. In large and symptomatic or recurrent cysts, excision or marsupialization is indicated [
4]. Cyst marsupialization is a simple minimally invasive procedure, which creates minimal surgical scarring and results in the pathological diagnosis of a Gartner duct cyst. Long-term follow-up after such a procedure has proven its efficacy with no demonstrated side effects or recurrence [
11]. The management strategies for multiloculated recurrences include periodic surveillance, sclerotherapy, and marsupialization [
12]. In older patients, a mass wall biopsy is recommended to exclude neoplasia; however, malignant transformation of Gartner’s cysts is exceedingly rare [
13].