Skip to main content
Erschienen in: European Radiology 9/2016

18.12.2015 | Contrast Media

Contrast-induced nephropathy in CT: incidence, risk factors and strategies for prevention

verfasst von: Shu Min Tao, Julian L. Wichmann, U. Joseph Schoepf, Stephen R. Fuller, Guang Ming Lu, Long Jiang Zhang

Erschienen in: European Radiology | Ausgabe 9/2016

Einloggen, um Zugang zu erhalten

Abstract

In the past, a high percentage of hospital-acquired renal failure was attributed to contrast media. That position is now very controversial. Recently, doubts have been raised regarding the real relationship between acute kidney injury and intravenous contrast media administration. Similarly, statements about specific methods of preventing contrast-inducing nephropathy have been challenged. This review article addresses the controversies of incidence, causation, and prevention in an attempt to help the practicing radiologist adopt methods for their own department.

Key Points

The reported CIN incidence ranges from 2–12 % following contrast-enhanced CT.
Studies without a non-contrast CT control group may overestimate CIN incidence.
Development and application of a comprehensive CIN prevention strategy is recommended.
Literatur
1.
Zurück zum Zitat Bartels ED, Brun GC, Gammeltoft A et al (1954) Acute anuria following intravenous pyelography in a patient with myelomatosis. Acta Med Scand 150:297–302CrossRefPubMed Bartels ED, Brun GC, Gammeltoft A et al (1954) Acute anuria following intravenous pyelography in a patient with myelomatosis. Acta Med Scand 150:297–302CrossRefPubMed
2.
Zurück zum Zitat Haveman JW, Gansevoort RT, Bongaerts AH et al (2006) Low incidence of nephropathy in surgical ICU patients receiving intravenous contrast: a retrospective analysis. Intensive Care Med 32:1199–1205CrossRefPubMed Haveman JW, Gansevoort RT, Bongaerts AH et al (2006) Low incidence of nephropathy in surgical ICU patients receiving intravenous contrast: a retrospective analysis. Intensive Care Med 32:1199–1205CrossRefPubMed
3.
Zurück zum Zitat Deek H, Newton P, Sheerin N et al (2014) Contrast media induced nephropathy: a literature review of the available evidence and recommendations for practice. Aust Crit Care 27:166–171CrossRefPubMed Deek H, Newton P, Sheerin N et al (2014) Contrast media induced nephropathy: a literature review of the available evidence and recommendations for practice. Aust Crit Care 27:166–171CrossRefPubMed
4.
Zurück zum Zitat Chertow GM, Burdick E, Honour M et al (2005) Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol 16:3365–3370CrossRefPubMed Chertow GM, Burdick E, Honour M et al (2005) Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol 16:3365–3370CrossRefPubMed
5.
Zurück zum Zitat Kooiman J, Pasha SM, Zondag W et al (2012) Meta-analysis: serum creatinine changes following contrast enhanced CT imaging. Eur J Radiol 81:2554–2561CrossRefPubMed Kooiman J, Pasha SM, Zondag W et al (2012) Meta-analysis: serum creatinine changes following contrast enhanced CT imaging. Eur J Radiol 81:2554–2561CrossRefPubMed
6.
Zurück zum Zitat Mitchell AM, Jones AE, Tumlin JA et al (2012) Incidence of contrast-induced nephropathy after contrast-enhanced computed tomography in the outpatient setting. Clin J Am Soc Nephrol 5:4–9CrossRef Mitchell AM, Jones AE, Tumlin JA et al (2012) Incidence of contrast-induced nephropathy after contrast-enhanced computed tomography in the outpatient setting. Clin J Am Soc Nephrol 5:4–9CrossRef
7.
Zurück zum Zitat Lee J, Cho JY, Lee HJ et al (2014) Contrast-induced nephropathy in patients undergoing intravenous contrast-enhanced computed tomography in Korea: a multi-institutional study in 101487 patients. Korean J Radiol 15:456–463CrossRefPubMedPubMedCentral Lee J, Cho JY, Lee HJ et al (2014) Contrast-induced nephropathy in patients undergoing intravenous contrast-enhanced computed tomography in Korea: a multi-institutional study in 101487 patients. Korean J Radiol 15:456–463CrossRefPubMedPubMedCentral
8.
Zurück zum Zitat Davenport MS, Khalatbari S, Cohan RH et al (2013) Contrast material-induced nephrotoxicity and intravenous low-osmolality iodinated contrast material: risk stratification by using estimated glomerular filtration rate. Radiology 268:719–728CrossRefPubMed Davenport MS, Khalatbari S, Cohan RH et al (2013) Contrast material-induced nephrotoxicity and intravenous low-osmolality iodinated contrast material: risk stratification by using estimated glomerular filtration rate. Radiology 268:719–728CrossRefPubMed
9.
Zurück zum Zitat Kooiman J, Sijpkens YW, van Buren M et al (2014) Randomised trial of no hydration vs. sodium bicarbonate hydration in patients with chronic kidney disease undergoing acute computed tomography-pulmonary angiography. J Thromb Haemost 12:1658–1666CrossRefPubMed Kooiman J, Sijpkens YW, van Buren M et al (2014) Randomised trial of no hydration vs. sodium bicarbonate hydration in patients with chronic kidney disease undergoing acute computed tomography-pulmonary angiography. J Thromb Haemost 12:1658–1666CrossRefPubMed
10.
Zurück zum Zitat Andreucci M, Solomon R, Tasanarong A (2014) Side effects of radiographic contrast media: pathogenesis, risk factors, and prevention. Biomed Res Int. 741018 Andreucci M, Solomon R, Tasanarong A (2014) Side effects of radiographic contrast media: pathogenesis, risk factors, and prevention. Biomed Res Int. 741018
11.
Zurück zum Zitat Lima FO, Lev MH, Levy RA et al (2010) Functional contrast-enhanced CT for evaluation of acute ischemic stroke does not increase the risk of contrast-induced nephropathy. AJNR Am J Neuroradiol 31:817–821CrossRefPubMed Lima FO, Lev MH, Levy RA et al (2010) Functional contrast-enhanced CT for evaluation of acute ischemic stroke does not increase the risk of contrast-induced nephropathy. AJNR Am J Neuroradiol 31:817–821CrossRefPubMed
12.
Zurück zum Zitat McGillicuddy EA, Schuster KM, Kaplan LJ et al (2010) Contrast-induced nephropathy in elderly trauma patients. J Trauma 68:294–297CrossRefPubMed McGillicuddy EA, Schuster KM, Kaplan LJ et al (2010) Contrast-induced nephropathy in elderly trauma patients. J Trauma 68:294–297CrossRefPubMed
13.
Zurück zum Zitat Kuhn MJ, Chen N, Sahani DV et al (2008) The PREDICT study: a randomized double-blind comparison of contrast-induced nephropathy after low- or isoosmolar contrast agent exposure. AJR Am J Roentgenol 191:151–157CrossRefPubMed Kuhn MJ, Chen N, Sahani DV et al (2008) The PREDICT study: a randomized double-blind comparison of contrast-induced nephropathy after low- or isoosmolar contrast agent exposure. AJR Am J Roentgenol 191:151–157CrossRefPubMed
14.
Zurück zum Zitat Stacul F, van der Molen AJ, Reimer P et al (2011) Contrast induced nephropathy: updated ESUR Contrast Media Safety Committee guidelines. Eur Radiol 21:2527–2541CrossRefPubMed Stacul F, van der Molen AJ, Reimer P et al (2011) Contrast induced nephropathy: updated ESUR Contrast Media Safety Committee guidelines. Eur Radiol 21:2527–2541CrossRefPubMed
15.
Zurück zum Zitat McDonald JS, McDonald RJ, Carter RE et al (2014) Risk of intravenous contrast material-mediated acute kidney injury: a propensity score-matched study stratified by baseline-estimated glomerular filtration rate. Radiology 271:65–73CrossRefPubMed McDonald JS, McDonald RJ, Carter RE et al (2014) Risk of intravenous contrast material-mediated acute kidney injury: a propensity score-matched study stratified by baseline-estimated glomerular filtration rate. Radiology 271:65–73CrossRefPubMed
16.
Zurück zum Zitat McDonald RJ, McDonald JS, Carter RE et al (2014) Intravenous contrast material exposure is not an independent risk factor for dialysis or mortality. Radiology 273:714–725CrossRefPubMed McDonald RJ, McDonald JS, Carter RE et al (2014) Intravenous contrast material exposure is not an independent risk factor for dialysis or mortality. Radiology 273:714–725CrossRefPubMed
17.
Zurück zum Zitat Morcos SK, Thomsen HS, Webb JA (1999) Contrast-media-induced nephrotoxicity: a consensus report. Contrast Media Safety Committee, European Society of Urogenital Radiology (ESUR). Eur Radiol 8:1602–1613CrossRef Morcos SK, Thomsen HS, Webb JA (1999) Contrast-media-induced nephrotoxicity: a consensus report. Contrast Media Safety Committee, European Society of Urogenital Radiology (ESUR). Eur Radiol 8:1602–1613CrossRef
19.
Zurück zum Zitat Mehta RL, Kellum JA, Shah SV et al (2007) Acute Kidney Injury Network. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 2:R31CrossRef Mehta RL, Kellum JA, Shah SV et al (2007) Acute Kidney Injury Network. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 2:R31CrossRef
20.
Zurück zum Zitat Ohno I, Hayashi H, Aonuma K et al (2013) Guidelines on the use of iodinated contrast media in patients with kidney disease 2012: digest version: JSN, JRS, and JCS Joint Working Group. Clin Exp Nephrol 17:441–479CrossRefPubMed Ohno I, Hayashi H, Aonuma K et al (2013) Guidelines on the use of iodinated contrast media in patients with kidney disease 2012: digest version: JSN, JRS, and JCS Joint Working Group. Clin Exp Nephrol 17:441–479CrossRefPubMed
21.
Zurück zum Zitat Sendeski MM (2011) Pathophysiology of renal tissue damage by iodinated contrast media. Clin Exp Pharmacol Physiol 38:292–299CrossRefPubMed Sendeski MM (2011) Pathophysiology of renal tissue damage by iodinated contrast media. Clin Exp Pharmacol Physiol 38:292–299CrossRefPubMed
22.
Zurück zum Zitat Nazıroğlu M, Yoldaş N, Uzgur EN et al (2013) Role of contrast media on oxidative stress, Ca(2+) signaling and apoptosis in kidney. J Membr Biol 246:91–100CrossRefPubMed Nazıroğlu M, Yoldaş N, Uzgur EN et al (2013) Role of contrast media on oxidative stress, Ca(2+) signaling and apoptosis in kidney. J Membr Biol 246:91–100CrossRefPubMed
23.
Zurück zum Zitat Sadat U (2013) Radiographic contrast-media-induced acute kidney injury: pathophysiology and prophylactic strategies. ISRN Radiol 496438 Sadat U (2013) Radiographic contrast-media-induced acute kidney injury: pathophysiology and prophylactic strategies. ISRN Radiol 496438
24.
Zurück zum Zitat Chang CF, Lin CC (2013) Current concepts of contrast-induced nephropathy: a brief review. J Chin Med Assoc 76:673–681CrossRefPubMed Chang CF, Lin CC (2013) Current concepts of contrast-induced nephropathy: a brief review. J Chin Med Assoc 76:673–681CrossRefPubMed
25.
Zurück zum Zitat Zhang Y, Wang J, Yang X et al (2012) The serial effect of iodinated contrast media on renal hemodynamics and oxygenation as evaluated by ASL and BOLD MRI. Contrast Media Mol Imaging 7:418–425CrossRefPubMed Zhang Y, Wang J, Yang X et al (2012) The serial effect of iodinated contrast media on renal hemodynamics and oxygenation as evaluated by ASL and BOLD MRI. Contrast Media Mol Imaging 7:418–425CrossRefPubMed
26.
Zurück zum Zitat Cronin RE (2010) Contrast-induced nephropathy: pathogenesis and prevention. Pediatr Nephrol 25:191–204CrossRefPubMed Cronin RE (2010) Contrast-induced nephropathy: pathogenesis and prevention. Pediatr Nephrol 25:191–204CrossRefPubMed
27.
28.
Zurück zum Zitat Solomon R, Solomon R, Dauerman HL (2011) Contrast–induced acute kidney injury. Circulation 122:2451–2455CrossRef Solomon R, Solomon R, Dauerman HL (2011) Contrast–induced acute kidney injury. Circulation 122:2451–2455CrossRef
29.
Zurück zum Zitat Meinel FG, De Cecco CN, Schoepf UJ et al (2014) Contrast–induced acute kidney injury: definition, epidemiology, and outcome. Biomed Res Int 859328 Meinel FG, De Cecco CN, Schoepf UJ et al (2014) Contrast–induced acute kidney injury: definition, epidemiology, and outcome. Biomed Res Int 859328
30.
Zurück zum Zitat Murakami R, Hayashi H, Sugizaki K et al (2012) Contrast–induced nephropathy in patients with renal insufficiency undergoing contrast–enhanced MDCT. Eur Radiol 22:2147–2152CrossRefPubMed Murakami R, Hayashi H, Sugizaki K et al (2012) Contrast–induced nephropathy in patients with renal insufficiency undergoing contrast–enhanced MDCT. Eur Radiol 22:2147–2152CrossRefPubMed
31.
Zurück zum Zitat Bruce RJ, Djamali A, Shinki K et al (2009) Background fluctuation of kidney function versus contrast–induced nephrotoxicity. AJR Am J Roentgenol 92:711–718CrossRef Bruce RJ, Djamali A, Shinki K et al (2009) Background fluctuation of kidney function versus contrast–induced nephrotoxicity. AJR Am J Roentgenol 92:711–718CrossRef
32.
Zurück zum Zitat McDonald JS, McDonald RJ, Comin J et al (2013) Frequency of acute kidney injury following intravenous contrast medium administration: a systematic review and meta-analysis. Radiology 267:119–128CrossRefPubMed McDonald JS, McDonald RJ, Comin J et al (2013) Frequency of acute kidney injury following intravenous contrast medium administration: a systematic review and meta-analysis. Radiology 267:119–128CrossRefPubMed
33.
Zurück zum Zitat Newhouse JH, Kho D, Rao QA et al (2008) Frequency of serum creatinine changes in the absence of iodinated contrast material: implications for studies of contrast nephrotoxicity. AJR Am J Roentgenol 191:376–382CrossRefPubMed Newhouse JH, Kho D, Rao QA et al (2008) Frequency of serum creatinine changes in the absence of iodinated contrast material: implications for studies of contrast nephrotoxicity. AJR Am J Roentgenol 191:376–382CrossRefPubMed
34.
Zurück zum Zitat Moos SI, van Vemde DN, Stoker J et al (2013) Contrast induced nephropathy in patients undergoing intravenous (IV) contrast enhanced computed tomography (CECT) and the relationship with risk factors: a meta-analysis. Eur J Radiol 82:e387–e399CrossRefPubMed Moos SI, van Vemde DN, Stoker J et al (2013) Contrast induced nephropathy in patients undergoing intravenous (IV) contrast enhanced computed tomography (CECT) and the relationship with risk factors: a meta-analysis. Eur J Radiol 82:e387–e399CrossRefPubMed
35.
Zurück zum Zitat Moos SI, Stoker J, Nagan G et al (2014) Prediction of presence of kidney disease in a general patient population undergoing intravenous iodinated contrast enhanced computed tomography. Eur Radiol 24:1266–1275PubMed Moos SI, Stoker J, Nagan G et al (2014) Prediction of presence of kidney disease in a general patient population undergoing intravenous iodinated contrast enhanced computed tomography. Eur Radiol 24:1266–1275PubMed
36.
Zurück zum Zitat Herts BR, Schneider E, Poggio ED et al (2008) Identifying outpatients with renal insufficiency before contrast-enhanced CT by using estimated glomerular filtration rates versus serum creatinine levels. Radiology 248:106–113CrossRefPubMed Herts BR, Schneider E, Poggio ED et al (2008) Identifying outpatients with renal insufficiency before contrast-enhanced CT by using estimated glomerular filtration rates versus serum creatinine levels. Radiology 248:106–113CrossRefPubMed
37.
Zurück zum Zitat Cicin I, Erdogan B, Gulsen E et al (2014) Incidence of contrast-induced nephropathy in hospitalised patients with cancer. Eur Radiol 24:184–190CrossRefPubMed Cicin I, Erdogan B, Gulsen E et al (2014) Incidence of contrast-induced nephropathy in hospitalised patients with cancer. Eur Radiol 24:184–190CrossRefPubMed
38.
Zurück zum Zitat Shin DH, Choi DJ, Youn TJ et al (2011) Comparison of contrast-induced nephrotoxicity of iodixanol and iopromide in patients with renal insufficiency undergoing coronary angiography. Am J Cardiol 108:189–194CrossRefPubMed Shin DH, Choi DJ, Youn TJ et al (2011) Comparison of contrast-induced nephrotoxicity of iodixanol and iopromide in patients with renal insufficiency undergoing coronary angiography. Am J Cardiol 108:189–194CrossRefPubMed
39.
Zurück zum Zitat Prasad V, Gandhi D, Stokum C et al (2014) Incidence of contrast material–induced nephropathy after neuroendovascular procedures. Radiology 273:853–858CrossRefPubMed Prasad V, Gandhi D, Stokum C et al (2014) Incidence of contrast material–induced nephropathy after neuroendovascular procedures. Radiology 273:853–858CrossRefPubMed
40.
Zurück zum Zitat Weisbord SD, Mor MK, Resnick A et al (2008) Incidence and outcomes of contrast-induced AKI following computed tomography. Clin J Am Soc Nephrol 3:1274–1281CrossRefPubMedPubMedCentral Weisbord SD, Mor MK, Resnick A et al (2008) Incidence and outcomes of contrast-induced AKI following computed tomography. Clin J Am Soc Nephrol 3:1274–1281CrossRefPubMedPubMedCentral
41.
Zurück zum Zitat Rudnick M, Feldman H (2008) Contrast-induced nephropathy: what are the true clinical consequences? Clin J Am Soc Nephrol 3:263–272CrossRefPubMed Rudnick M, Feldman H (2008) Contrast-induced nephropathy: what are the true clinical consequences? Clin J Am Soc Nephrol 3:263–272CrossRefPubMed
42.
Zurück zum Zitat Seabra VF, Balk EM, Liangos O et al (2008) Timing of renal replacement therapy initiation in acute renal failure: a meta-analysis. Am J Kidney Dis 52:272–284CrossRefPubMed Seabra VF, Balk EM, Liangos O et al (2008) Timing of renal replacement therapy initiation in acute renal failure: a meta-analysis. Am J Kidney Dis 52:272–284CrossRefPubMed
43.
Zurück zum Zitat Iyem H, Tavli M, Akcicek F et al (2009) Importance of early dialysis for acute renal failure after an open-heart surgery. Hemodial Int 13:55–61CrossRefPubMed Iyem H, Tavli M, Akcicek F et al (2009) Importance of early dialysis for acute renal failure after an open-heart surgery. Hemodial Int 13:55–61CrossRefPubMed
44.
Zurück zum Zitat Schefold JC, von Haehling S, Pschowski R et al (2014) A The effect of continuous versus intermittent renal replacement therapy on the outcome of critically ill patients with acute renal failure (CONVINT): a prospective randomized controlled trial. Crit Care 18:R11CrossRefPubMedPubMedCentral Schefold JC, von Haehling S, Pschowski R et al (2014) A The effect of continuous versus intermittent renal replacement therapy on the outcome of critically ill patients with acute renal failure (CONVINT): a prospective randomized controlled trial. Crit Care 18:R11CrossRefPubMedPubMedCentral
45.
Zurück zum Zitat Liu YH, Liu Y, Tan N et al (2015) Contrast-induced nephropathy following chronic total occlusion percutaneous coronary intervention in patients with chronic kidney disease. Eur Radiol 25:2274–2281CrossRefPubMed Liu YH, Liu Y, Tan N et al (2015) Contrast-induced nephropathy following chronic total occlusion percutaneous coronary intervention in patients with chronic kidney disease. Eur Radiol 25:2274–2281CrossRefPubMed
46.
Zurück zum Zitat Kooiman J, Sijpkens YW, de Vries JP et al (2014) A randomized comparison of 1-h sodium bicarbonate hydration versus standard peri-procedural saline hydration in patients with chronic kidney disease undergoing intravenous contrast-enhanced computerized tomography. Nephrol Dial Transplant 29:1029–1036CrossRefPubMed Kooiman J, Sijpkens YW, de Vries JP et al (2014) A randomized comparison of 1-h sodium bicarbonate hydration versus standard peri-procedural saline hydration in patients with chronic kidney disease undergoing intravenous contrast-enhanced computerized tomography. Nephrol Dial Transplant 29:1029–1036CrossRefPubMed
47.
Zurück zum Zitat Weisbord SD, Palevsky PM (2008) Prevention of contrast-induced nephropathy with volume expansion. Clin J Am Soc Nephrol 3:273–280CrossRefPubMed Weisbord SD, Palevsky PM (2008) Prevention of contrast-induced nephropathy with volume expansion. Clin J Am Soc Nephrol 3:273–280CrossRefPubMed
48.
Zurück zum Zitat Jang JS, Jin HY, Seo JS et al (2012) Sodium bicarbonate therapy for the prevention of contrast-induced acute kidney injury – a systematic review and meta-analysis. Circ J 76:2255–2265CrossRefPubMed Jang JS, Jin HY, Seo JS et al (2012) Sodium bicarbonate therapy for the prevention of contrast-induced acute kidney injury – a systematic review and meta-analysis. Circ J 76:2255–2265CrossRefPubMed
49.
Zurück zum Zitat Balemans CE, Reichert LJ, van Schelven BI et al (2012) Epidemiology of contrast material-induced nephropathy in the era of hydration. Radiology 263:706–713CrossRefPubMed Balemans CE, Reichert LJ, van Schelven BI et al (2012) Epidemiology of contrast material-induced nephropathy in the era of hydration. Radiology 263:706–713CrossRefPubMed
50.
Zurück zum Zitat Nijssen EC, Vermeeren MA, Janssen MM et al (2012) Contrast material-induced nephropathy in the era of hydration. Radiology 265:978–979CrossRefPubMed Nijssen EC, Vermeeren MA, Janssen MM et al (2012) Contrast material-induced nephropathy in the era of hydration. Radiology 265:978–979CrossRefPubMed
51.
Zurück zum Zitat Kama A, Yılmaz S, Yaka E et al (2014) Comparison of short-term infusion regimens of N-acetylcysteine plus intravenous fluids, sodium bicarbonate plus intravenous fluids, and intravenous fluids alone for prevention of contrast-induced nephropathy in the emergency department. Acad Emerg Med 21:615–622CrossRefPubMed Kama A, Yılmaz S, Yaka E et al (2014) Comparison of short-term infusion regimens of N-acetylcysteine plus intravenous fluids, sodium bicarbonate plus intravenous fluids, and intravenous fluids alone for prevention of contrast-induced nephropathy in the emergency department. Acad Emerg Med 21:615–622CrossRefPubMed
52.
Zurück zum Zitat Hiremath S, Akbari A, Shabana W et al (2013) Prevention of contrast-induced acute kidney injury: is simple oral hydration similar to intravenous? A systematic review of the evidence. PLoS One 8:e60009CrossRefPubMedPubMedCentral Hiremath S, Akbari A, Shabana W et al (2013) Prevention of contrast-induced acute kidney injury: is simple oral hydration similar to intravenous? A systematic review of the evidence. PLoS One 8:e60009CrossRefPubMedPubMedCentral
53.
Zurück zum Zitat Traub SJ, Mitchell AM, Jones AE et al (2013) N-acetylcysteine plus intravenous fluids versus intravenous fluids alone to prevent contrast-induced nephropathy in emergency computed tomography. Ann Emerg Med 62:511–520CrossRefPubMed Traub SJ, Mitchell AM, Jones AE et al (2013) N-acetylcysteine plus intravenous fluids versus intravenous fluids alone to prevent contrast-induced nephropathy in emergency computed tomography. Ann Emerg Med 62:511–520CrossRefPubMed
54.
Zurück zum Zitat Sadat U, Usman A, Gillard JH et al (2013) Does ascorbic acid protect against contrast-induced acute kidney injury in patients undergoing coronary angiography: a systematic review with meta-analysis of randomized, controlled trials. J Am Coll Cardiol 62:2167–2175CrossRefPubMed Sadat U, Usman A, Gillard JH et al (2013) Does ascorbic acid protect against contrast-induced acute kidney injury in patients undergoing coronary angiography: a systematic review with meta-analysis of randomized, controlled trials. J Am Coll Cardiol 62:2167–2175CrossRefPubMed
55.
Zurück zum Zitat Spatz C, Saadulla L, Lapsiwala A et al (2012) Effect of renin-angiotensin-aldosterone system blockade therapy on incidence of contrast-induced nephropathy in patients with chronic kidney disease. Iran J Kidney Dis 6:432–436PubMedPubMedCentral Spatz C, Saadulla L, Lapsiwala A et al (2012) Effect of renin-angiotensin-aldosterone system blockade therapy on incidence of contrast-induced nephropathy in patients with chronic kidney disease. Iran J Kidney Dis 6:432–436PubMedPubMedCentral
56.
Zurück zum Zitat Marenzi G, Ferrari C, Marana I et al (2012) Prevention of contrast nephropathy by furosemide with matched hydration: the MYTHOS (Induced Diuresis With Matched Hydration Compared to Standard Hydration for Contrast Induced Nephropathy Prevention) trial. JACC Cardiovasc Interv 5:90–97CrossRefPubMed Marenzi G, Ferrari C, Marana I et al (2012) Prevention of contrast nephropathy by furosemide with matched hydration: the MYTHOS (Induced Diuresis With Matched Hydration Compared to Standard Hydration for Contrast Induced Nephropathy Prevention) trial. JACC Cardiovasc Interv 5:90–97CrossRefPubMed
57.
Zurück zum Zitat Wu MY, Hsiang HF, Wong CS et al (2013) The effectiveness of N-Acetylcysteine in preventing contrast-induced nephropathy in patients undergoing contrast-enhanced computed tomography: a meta-analysis of randomized controlled trials. Int Urol Nephrol 45:1309–1318CrossRefPubMed Wu MY, Hsiang HF, Wong CS et al (2013) The effectiveness of N-Acetylcysteine in preventing contrast-induced nephropathy in patients undergoing contrast-enhanced computed tomography: a meta-analysis of randomized controlled trials. Int Urol Nephrol 45:1309–1318CrossRefPubMed
58.
Zurück zum Zitat Hsu TF, Huang MK, Yu SH et al (2012) N-acetylcysteine for the prevention of contrast-induced nephropathy in the emergency department. Intern Med 51:2709–2714CrossRefPubMed Hsu TF, Huang MK, Yu SH et al (2012) N-acetylcysteine for the prevention of contrast-induced nephropathy in the emergency department. Intern Med 51:2709–2714CrossRefPubMed
59.
Zurück zum Zitat Poletti PA, Platon A, De Seigneux S et al (2013) N-acetylcysteine does not prevent contrast nephropathy in patients with renal impairment undergoing emergency CT: a randomized study. BMC Nephrol 14:119CrossRefPubMedPubMedCentral Poletti PA, Platon A, De Seigneux S et al (2013) N-acetylcysteine does not prevent contrast nephropathy in patients with renal impairment undergoing emergency CT: a randomized study. BMC Nephrol 14:119CrossRefPubMedPubMedCentral
60.
Zurück zum Zitat Richenberg J (2012) How to reduce nephropathy following contrast-enhanced CT: a lesson in policy implementation. Clin Radiol 67:1136–1145CrossRefPubMed Richenberg J (2012) How to reduce nephropathy following contrast-enhanced CT: a lesson in policy implementation. Clin Radiol 67:1136–1145CrossRefPubMed
61.
Zurück zum Zitat Lu GM, Luo S, Meinel FG et al (2014) High-pitch computed tomography pulmonary angiography with iterative reconstruction at 80 kVp and 20 mL contrast agent volume. Eur Radiol 24:3260–3268CrossRefPubMed Lu GM, Luo S, Meinel FG et al (2014) High-pitch computed tomography pulmonary angiography with iterative reconstruction at 80 kVp and 20 mL contrast agent volume. Eur Radiol 24:3260–3268CrossRefPubMed
62.
Zurück zum Zitat Luo S, Zhang LJ, Meinel FG et al (2014) Low tube voltage and low contrast material volume cerebral CT angiography. Eur Radiol 24:1677–1685CrossRefPubMed Luo S, Zhang LJ, Meinel FG et al (2014) Low tube voltage and low contrast material volume cerebral CT angiography. Eur Radiol 24:1677–1685CrossRefPubMed
63.
Zurück zum Zitat Zhang LJ, Qi L, Wang J, Tang CX et al (2014) Feasibility of prospectively ECG-triggered high-pitch coronary CT angiography with 30 mL iodinated contrast agent at 70 kVp: initial experience. Eur Radiol 24:1537–1546CrossRefPubMed Zhang LJ, Qi L, Wang J, Tang CX et al (2014) Feasibility of prospectively ECG-triggered high-pitch coronary CT angiography with 30 mL iodinated contrast agent at 70 kVp: initial experience. Eur Radiol 24:1537–1546CrossRefPubMed
64.
Zurück zum Zitat Geyer LL, Schoepf UJ, Meinel FG et al (2015) State of the Art: Iterative CT reconstruction techniques. Radiology 276:339–357CrossRefPubMed Geyer LL, Schoepf UJ, Meinel FG et al (2015) State of the Art: Iterative CT reconstruction techniques. Radiology 276:339–357CrossRefPubMed
Metadaten
Titel
Contrast-induced nephropathy in CT: incidence, risk factors and strategies for prevention
verfasst von
Shu Min Tao
Julian L. Wichmann
U. Joseph Schoepf
Stephen R. Fuller
Guang Ming Lu
Long Jiang Zhang
Publikationsdatum
18.12.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
European Radiology / Ausgabe 9/2016
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-015-4155-8

Weitere Artikel der Ausgabe 9/2016

European Radiology 9/2016 Zur Ausgabe

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.