Anzeige
Erschienen in:
01.07.2007 | Original Article
Coronary magnetic resonance angiography and vessel wall imaging in children with Kawasaki disease
Erschienen in: Pediatric Radiology | Ausgabe 7/2007
Einloggen, um Zugang zu erhaltenAbstract
Background
In patients with Kawasaki disease (KD) serial evaluation of the distribution and size of coronary artery aneurysms (CAA) is necessary for risk stratification and therapeutic management.
Objective
To apply whole-heart coronary MR angiography (CMRA) and black-blood coronary vessel wall imaging in children with KD.
Materials and methods
Six children (mean age 4.6 years, range 2.5–7.8 years) with KD underwent CMRA using a free-breathing, T2-prepared, three-dimensional steady-state free-precession (3D-SSFP), whole-heart approach with navigator gating and tracking. Vessel walls were imaged with an ECG-triggered and navigator-gated double inversion recovery (DIR) black-blood segmented turbo spin-echo sequence.
Results
There was complete agreement between CMRA and conventional angiography (n=6) in the detection of CAA (n=15). Excellent agreement was found between the two techniques in determining the maximal diameter (mean difference 0.2±0.7 mm), length (mean difference 0.1±0.8 mm) and distance from the ostium (mean difference −0.8±2.1 mm) of the CAAs. In all subjects with a CAA, abnormally thickened vessel walls were found (2.5±0.5 mm).
Conclusions
CMRA accurately defines CAA in free-breathing sedated children with KD using the whole-heart approach and detects abnormally thickened vessel walls. This technique may reduce the need for serial X-ray coronary angiography, and improve risk stratification and monitoring of therapy.