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Erschienen in:
14.11.2018 | Correction
Correction to: Chronic Aichi Virus Infection in a Patient with X-Linked Agammaglobulinemia
Erschienen in: Journal of Clinical Immunology | Ausgabe 8/2018
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Correction to: Journal of Clinical Immunology
Fig. 1
CD8+ T cells in the proband XLA patient are skewed towards a memory phenotype with evidence of exhaustion and/or senescence. PBMCs from healthy controls, an XLA control and our XLA patient were labeled with mAbs against CD4, CD8, CD45RA, CCR7, CD38, HLA-DR, HLA-ABC, CD95, CD57, and CX3CR1. Proportions of (A) CD4+ and CD8+ T cell populations, as well as subsets of naïve (CD45RA+CCR7+), central memory (CM, CD45RA−CCR7+), effector memory (EM, CD45RA−CCR7−), and terminally differentiated effector memory cells expressing CD45RA (EMRA, CD45RA+CCR7−), (B) CD4+, and (C) CD8+ T cells were delineated. Differential expression of the activation markers CD38 (D), HLA-DR (E), and HLA-ABC (F), as well as the exhaustion/senescence markers CD95 (G), CD57 (H) and CX3CR1 (I) on naïve, TCM, TEM and TEMRA CD8+ T cells were determined. Values represent the geometric MFI
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