Correction to: Sepsis increases perioperative metastases in a murine model
verfasst von:
Lee-Hwa Tai, Abhirami A. Ananth, Rashmi Seth, Almohanad Alkayyal, Jiqing Zhang, Christiano Tanese de Souza, Phillip Staibano, Michael A. Kennedy, Rebecca C. Auer
It has been highlighted that the original manuscript [1] contains a typesetting error in Fig. 1 and the Fig. 1c panel has been inadvertently duplicated in panel Fig. 1d. This does not affect the results and conclusions of the article. The correct version of Fig. 1 is included with this Correction. The original article has been updated.
Fig. 1
Hemorrhagic shock does not increase metastatic disease. aExperimental overview. BALB/c mice were bled through the saphenous vein (indicated by the white arrow) and subsequently injected intravenously (IV) through the tail vein with 3 × 105 CT26LacZ cells. Approximately 1 h later, surgical stress (sx) was generated by laparotomy (Lap) (5 cm incision). Mice were sacrificed at 72 h to quantify lung metastases. bBlood pressure is reduced following surgical stress and blood loss. Blood pressure (mmHg) was measured following a 5-day training period (Day 1–5), prior to bleeding (Pre), immediately following bleeding (Post-BL), and immediately following surgical stress (Post-Sx and BL, n = 3). cBlood loss increases metastatic burden. Lung metastases were measured on Day 3 following no blood loss (no BL, n = 3) or 20% (20% BL, n = 3) or 30% blood loss (30% BL, n = 4). dBlood loss does not increase metastatic disease in conjunction with surgical stress. Lung metastases were measure on Day 3 in mice that did not undergo surgical stress (No Sx, n = 5) and animals undergoing a laparotomy (Lap, n = 4) alone or in combination with 30% blood loss (Lap + 30% BL, n = 5). Error bars represent ± SEM
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Correction to: Sepsis increases perioperative metastases in a murine model
verfasst von
Lee-Hwa Tai Abhirami A. Ananth Rashmi Seth Almohanad Alkayyal Jiqing Zhang Christiano Tanese de Souza Phillip Staibano Michael A. Kennedy Rebecca C. Auer
