Correlation between inguinal and ventral hernia repair outcomes and pre-existing comorbidity clusters: ACS-NSQIP study
- 01.12.2026
- Original Article
Erschienen in:
- Verfasst von
- Wendy Wang
- Javairia Haq
- Em Long-Mills
- Dmitry Tumin
- Maryna Chumakova-Orin
- Erschienen in
- Hernia | Ausgabe 1/2026
Abstract
Purpose
Pre-existing comorbidities may negatively impact surgical outcomes, yet risk profiles based on combinations of comorbidities are underutilized. We aimed to identify comorbidity clusters associated with adverse surgical outcomes after inguinal or ventral hernia repair.
Methods
We performed a retrospective cohort study using the ACS-NSQIP database (2016–2023). Adults undergoing elective inguinal or ventral hernia repair were identified using CPT and ICD-10 codes. Latent class analysis (LCA) identified subgroups of patients who shared similar patterns of comorbidities. Outcomes included postoperative complications, hospital length of stay, and 30-day mortality.
Results
Among 224,522 patients, LCA identified six profiles: no comorbidities, smoking, bleeding disorder or congestive heart failure (CHF), obesity with diabetes or smoking, obesity without diabetes or smoking, and hypertension. Compared with no comorbidities, risk of complications was higher in the smoking (OR 1.32, 95% CI 1.18–1.49), bleeding disorder or CHF (OR 1.68, 95% CI 1.23–2.29), obesity with diabetes or smoking (OR 1.41, 95% CI 1.25–1.58), obesity without diabetes or smoking (OR 1.17, 95% CI 1.06–1.29), and hypertension (OR 1.16, 95% CI 1.05–1.28) clusters. These clusters also had longer hospital stays compared to patients with no comorbidities. 30-day mortality was significantly increased in the “bleeding disorder or CHF” (OR 3.22, 95% CI 1.52–6.84) and hypertension (OR 1.66, 95% CI 1.09–2.54) clusters.
Conclusion
Distinct comorbidity clusters predict complications, prolonged hospitalization, and mortality following hernia repair. Incorporating comorbidity profiles into preoperative risk stratification may enhance surgical decision-making, allow targeted interventions, and improve outcomes in high-risk patients.
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- Titel
- Correlation between inguinal and ventral hernia repair outcomes and pre-existing comorbidity clusters: ACS-NSQIP study
- Verfasst von
-
Wendy Wang
Javairia Haq
Em Long-Mills
Dmitry Tumin
Maryna Chumakova-Orin
- Publikationsdatum
- 01.12.2026
- Verlag
- Springer Paris
- Erschienen in
-
Hernia / Ausgabe 1/2026
Print ISSN: 1265-4906
Elektronische ISSN: 1248-9204 - DOI
- https://doi.org/10.1007/s10029-025-03539-w
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