Open Access 29.07.2017 | Original Article

# Cortical morphology of the pars opercularis and its relationship to motor-inhibitory performance in a longitudinal, developing cohort

Erschienen in: Brain Structure and Function | Ausgabe 1/2018

## Abstract

## Introduction

## Methods

### Participants

Demographics | Total | Male | Female |
---|---|---|---|

Number of participants | 110 | 59 | 51 |

Age [mean (SD) in years] | |||

Baseline (N = 110) | 6.9 (1.57) | 6.92 (1.41) | 6.87 (1.76) |

Time point 2 (N = 82) | 7.90 (1.45) | 7.95 (1.29) | 7.85 (1.63) |

Time point 3 (N = 32) | 9.07 (1.31) | 9.26 (1.27) | 8.90 (1.37) |

Time point 4 (N = 8) | 9.71 (1.30) | 9.83 (0.00) | 9.69 (1.41) |

Stop-signal reaction time [mean (SD) in ms] | |||

Baseline (N = 110) | 298.62 (114.33) | 316.06 (129.68) | 278.45 (90.64) |

Time point 2 (N = 82) | 258.50 (95.04) | 267.00 (99.84) | 248.65 (89.46) |

Time point 3 (N = 32) | 232.77 (98.38) | 241.52 (121.76) | 225.05 (75.13) |

Time point 4 (N = 8) | 232.47 (112.52) | 238.80 (0.00) | 231.56 (121.51) |

Handedness (R/L/Amb/NA) ^{a}
| 83/14/9/4 | ||

Race/ethnicity ^{b}
| |||

Caucasian | 54 | ||

African American | 5 | ||

Hispanic/Latino | 36 | ||

Asian | 13 | ||

Pacific Islander | 1 | ||

American Indian | 1 | ||

Mixed race | 22 | ||

Other | 3 |

### Stop-signal reaction time (SSRT)

### Neuroimaging

### Analysis

## Results

Fixed effects |
B value |
t value |
p value |
---|---|---|---|

Age ^{a}
| 0.10 | 7.62 | 0.0000*** |

Gender ^{a}
| −0.11 | −2.09 | 0.0389* |

Bilateral pars opercularis thickness ^{a}
| −0.27 | −1.33 | 0.1853 |

Scanner | 0.12 | 1.37 | 0.1682 |

Fixed effects |
B value |
t value |
p value |
---|---|---|---|

Age ^{a}
| 0.10 | 7.76 | 0.0000*** |

Gender ^{a}
| −0.11 | −1.94 | 0.0553 |

Bilateral pars opercularis surface area ^{a}
| 0.00 | 2.53 | 0.0127* |

Total cortical surface area ^{a}
| −0.00 | −0.84 | 0.4049 |

Scanner | 0.10 | 1.15 | 0.2535 |

Fixed effects |
B value |
t value |
p value |
---|---|---|---|

Age ^{a}
| 0.10 | 7.20 | 0.0000*** |

Gender ^{a}
| −0.11 | −1.97 | 0.0516 |

Bilateral pars opercularis surface area ^{a}
| 0.00 | 2.27 | 0.0250* |

Total cortical surface area ^{a}
| −0.00 | −0.91 | 0.3664 |

Age ^{a} × gender^{a}
| 0.04 | 1.53 | 0.1289 |

Age ^{a} × bilateral pars operc^{a}
| −0.00 | −0.56 | 0.5780 |

Gender ^{a} × bilateral pars operc^{a}
| 0.00 | 0.81 | 0.4191 |

Age ^{a} × gender^{a} × bilateral pars operc^{a}
| 0.00 | 1.49 | 0.1384 |

Scanner | 0.10 | 1.14 | 0.2574 |

B value |
t value |
p value | |
---|---|---|---|

(a) Left pars opercularis model | |||

Age ^{a}
| 0.11 | 7.92 | 0.0000*** |

Gender ^{a}
| −0.12 | −1.98 | 0.0505 |

Left pars opercularis surface area ^{a}
| 0.00 | 1.21 | 0.2295 |

Total cortical surface area ^{a}
| 0.00 | 0.10 | 0.9196 |

Scanner | 0.11 | 1.18 | 0.2399 |

(b) Right pars opercularis model | |||

Age ^{a}
| 0.10 | 7.75 | 0.0000*** |

Gender ^{a}
| −0.10 | −1.62 | 0.1084 |

Right pars opercularis surface area ^{a}
| 0.00 | 2.60 | 0.0106* |

Total cortical surface area ^{a}
| −0.00 | −0.73 | 0.4659 |

Scanner | 0.11 | 1.23 | 0.2214 |