Background
Objective
Methods
Direct costs
Healthcare costs covered by health insurance
Outpatient cost
Inpatient cost
Medication cost
Involuntary admission cost
Costs of provision under the Medical Care and Supervision Act in Japan
Social service cost
Indirect costs
Morbidity cost
Absenteeism and presenteeism
Male | Female | ||||||
---|---|---|---|---|---|---|---|
Age | Prevalence | SE | Distribution | Prevalence | SE | Distribution | |
Agoraphobia | 20-34 | 0.012 | 0.006 | beta | 0.017 | 0.007 | beta |
35-44 | 0.005 | 0.004 | beta | 0.007 | 0.005 | beta | |
45-54 | 0.003 | 0.003 | beta | 0.004 | 0.003 | beta | |
55-64 | 0.002 | 0.002 | beta | 0.003 | 0.002 | beta | |
65- | 0.001 | 0.002 | beta | 0.002 | 0.002 | beta | |
SAD | 20-34 | 0.018 | 0.008 | beta | 0.014 | 0.006 | beta |
35-44 | 0.013 | 0.007 | beta | 0.010 | 0.005 | beta | |
45-54 | 0.009 | 0.005 | beta | 0.007 | 0.004 | beta | |
55-64 | 0.004 | 0.003 | beta | 0.003 | 0.003 | beta | |
65- | 0.004 | 0.003 | beta | 0.003 | 0.002 | beta | |
Specifc Phobia | 20-34 | 0.032 | 0.010 | beta | 0.045 | 0.011 | beta |
35-44 | 0.034 | 0.011 | beta | 0.048 | 0.012 | beta | |
45-54 | 0.028 | 0.009 | beta | 0.040 | 0.009 | beta | |
55-64 | 0.021 | 0.007 | beta | 0.030 | 0.008 | beta | |
65- | 0.017 | 0.006 | beta | 0.024 | 0.006 | beta | |
Panic Disorder | 20-34 | 0.005 | 0.004 | beta | 0.009 | 0.005 | beta |
35-44 | 0.005 | 0.004 | beta | 0.008 | 0.005 | beta | |
45-54 | 0.007 | 0.004 | beta | 0.013 | 0.005 | beta | |
55-64 | 0.001 | 0.001 | beta | 0.001 | 0.002 | beta | |
65- | 0.017 | 0.006 | beta | 0.024 | 0.006 | beta | |
GAD | 20-34 | 0.010 | 0.006 | beta | 0.016 | 0.006 | beta |
35-44 | 0.010 | 0.006 | beta | 0.016 | 0.007 | beta | |
45-54 | 0.009 | 0.005 | beta | 0.014 | 0.006 | beta | |
55-64 | 0.006 | 0.004 | beta | 0.010 | 0.005 | beta | |
65- | 0.003 | 0.002 | beta | 0.005 | 0.003 | beta |
Diagnosis | Lost work days because of absenteeism | Relative ratio of day-equivalents for presenteeism versus absenteeism | ||
---|---|---|---|---|
days (SE) | distribution | ratio | distribution | |
Agoraphobia | 7.3(6.14) | gamma | 3.26 | deterministic |
SAD | 7.3(6.14) | gamma | 3.26 | deterministic |
Specifc Phobia | 1.3(0.84) | gamma | 3.26 | deterministic |
Panic | 7.3(6.14) | gamma | 3.26 | deterministic |
GAD | 8.7(2.88) | gamma | 3.26 | deterministic |
male | female | |||
---|---|---|---|---|
Age | JPY | distribution | JPY | distribution |
20-24 | 12,788 | deterministic | 11,515 | deterministic |
25-29 | 16,180 | deterministic | 13,872 | deterministic |
30-34 | 19,411 | deterministic | 14,796 | deterministic |
35-39 | 22,777 | deterministic | 15,752 | deterministic |
40-44 | 25,992 | deterministic | 16,251 | deterministic |
45-49 | 27,686 | deterministic | 15,625 | deterministic |
50-54 | 27,731 | deterministic | 15,265 | deterministic |
55-59 | 25,631 | deterministic | 14,310 | deterministic |
60-64 | 17,484 | deterministic | 11,746 | deterministic |
65-69 | 14,586 | deterministic | 11,097 | deterministic |
70- | 16,178 | deterministic | 12,444 | deterministic |
-
an observational study performed in a large, representative, community sample taken from the general population, and
-
the rates of absenteeism and presenteeism were measured directly from the samples, and anxiety disorders was defined using a recent psychiatric diagnostic classification system, such as the ICD, or DSM, to distinguish anxiety from ill-defined psychological distress or stress as an outcome.
Unemployment cost
Male | ||||||
---|---|---|---|---|---|---|
Age | Employment rate (general population)*1 | Distribution | Employment rate (patients with anxiety disorders)(S.E.)*2 | Distribution*3 | Expected yearly earinings (general population) (JPY:thousand)*4 | Distribution |
20-24 | 0.639 | deterministic | 0.435 (0.101) | beta | 3,184 | deterministic |
25-29 | 0.885 | deterministic | 0.630 (0.070) | beta | 4,029 | deterministic |
30-34 | 0.924 | deterministic | 0.717 (0.058) | beta | 4,833 | deterministic |
35-39 | 0.934 | deterministic | 0.667 (0.059) | beta | 5,672 | deterministic |
40-44 | 0.941 | deterministic | 0.733 (0.051) | beta | 6,472 | deterministic |
45-49 | 0.941 | deterministic | 0.746 (0.056) | beta | 6,894 | deterministic |
50-54 | 0.929 | deterministic | 0.759 (0.078) | beta | 6,905 | deterministic |
55-59 | 0.892 | deterministic | 0.714 (0.075) | beta | 6,382 | deterministic |
60-64 | 0.725 | deterministic | 0.379 (0.089) | beta | 4,353 | deterministic |
65-69 | 0.478 | deterministic | 0.400 (0.096) | beta | 3,632 | deterministic |
70- | 0.202 | deterministic | 0.400 (0.096) | beta | 4,028 | deterministic |
Female
| ||||||
Age | Employment rate (general population)*1 | Distribution | Employment rate (patients with anxiety disorders)(S.E.)*2 | Distribution*3 | Expected yearly earinings (general population) (JPY:thousand)*4 | Distribution |
20-24 | 0.648 | deterministic | 0.380 (0.068) | beta | 2,815 | deterministic |
25-29 | 0.718 | deterministic | 0.548 (0.058) | beta | 3,392 | deterministic |
30-34 | 0.617 | deterministic | 0.469 (0.062) | beta | 3,618 | deterministic |
35-39 | 0.622 | deterministic | 0.435 (0.051) | beta | 3,851 | deterministic |
40-44 | 0.687 | deterministic | 0.394 (0.060) | beta | 3,973 | deterministic |
45-49 | 0.729 | deterministic | 0.333 (0.056) | beta | 3,820 | deterministic |
50-54 | 0.698 | deterministic | 0.451 (0.069) | beta | 3,732 | deterministic |
55-59 | 0.600 | deterministic | 0.311 (0.059) | beta | 3,499 | deterministic |
60-64 | 0.425 | deterministic | 0.135 (0.047) | beta | 2,872 | deterministic |
65-69 | 0.255 | deterministic | 0.075 (0.036) | beta | 2,713 | deterministic |
70- | 0.085 | deterministic | 0.075 (0.036) | beta | 3,043 | deterministic |
Mortality cost
Male | ||||||
---|---|---|---|---|---|---|
age | the number of suicides *1 | distribution | expected lifetime earning(JPY: thousand)* 2 | distribution | the rate of suicides caused by anxiety disorders (S.E.) *3 | distribution |
20-29 | 2,373 | deterministic | 121,766 | deterministic | 0.149 (0.041) | beta |
30-39 | 3,396 | deterministic | 119,104 | deterministic | 0.149 (0.041) | beta |
40-49 | 3,852 | deterministic | 94,737 | deterministic | 0.149 (0.041) | beta |
50-59 | 4,986 | deterministic | 52,633 | deterministic | 0.149 (0.041) | beta |
60- | 7,639 | deterministic | 11,489 | deterministic | 0.149 (0.041) | beta |
unkown | 204 | deterministic | 63,317 | deterministic | 0.149 (0.041) | beta |
Female
| ||||||
age | the number of suicides *1 | distribution | expected lifetime earning(JPY: thousand)* 2 | distribution | the rate of suicides caused by anxiety disorders (S.E.) *3 | distribution |
20-29 | 1,065 | deterministic | 57,818 | deterministic | 0.149 (0.041) | beta |
30-39 | 1,454 | deterministic | 50,972 | deterministic | 0.149 (0.041) | beta |
40-49 | 1,118 | deterministic | 38,805 | deterministic | 0.149 (0.041) | beta |
50-59 | 1,377 | deterministic | 20,822 | deterministic | 0.149 (0.041) | beta |
60- | 4,154 | deterministic | 4,704 | deterministic | 0.149 (0.041) | beta |
unkown | 20 | deterministic | 24,791 | deterministic | 0.149 (0.041) | beta |
Sensitivity analysis
Results
Direct costs
(JPY: million) | |||
---|---|---|---|
Inpatient | Outpatient | Total | |
Health care cost |
-
|
-
| 49,442 |
Health care cost under health insurance schema | 8,064 | 41,332 | 49,396 |
Treatment cost | 7,657 | 26,114 | 33,771 |
Medication cost | 407 | 15,218 | 15,625 |
Involantary admission cost The medical care and | 19 | 0 | 19 |
supervision act cost |
-
|
-
| 27 |
Social service cost |
-
|
-
| 244 |
Total | 49,686 |
Indirect costs
Morbidity cost
Absenteeism and presenteeism
(JPY: million) | ||
---|---|---|
mean | S.E. | |
Morbidity cost | 2,099,089 | 6,950 |
Absenteeism and presenteeism | 1,381,347 | 6,465 |
Unemployment cost | 717,743 | 2,070 |
Mortality cost | 244,395 | 944 |
Total indirect cost | 2,343,484 | 7,008 |
Unemployment cost
Mortality cost
Discussion and conclusions
Point estimate or Mean | S.E. | |||
---|---|---|---|---|
(JPY: million) | (USD: million) | (JPY: million) | (USD: million) | |
Direct cost
|
49,686
|
425
|
-
|
-
|
Health care cost | 49,442 | 423 | - | - |
Health care cost under health insurance schema | 49,396 | 423 | - | - |
Involuntary admission cost | 19 | 0.16 | - | - |
The medical care and supervision act cost | 27 | 0.23 | - | - |
Social service cost | 244 | 2.09 | - | - |
Indirect cost
|
2,343,484
|
20,064
|
7,008
|
60.00
|
Morbidity cost | 2,099,089 | 17,972 | 6,950 | 60 |
Absenteeism and Presenteeism | 1,381,347 | 11,827 | 6,465 | 55 |
Unemployment cost | 717,743 | 6,145 | 2,070 | 18 |
Mortality cost | 244,395 | 2,092 | 944 | 8.08 |
Total cost
|
2,393,170
|
20,489
|
7,008
|
60.00
|