Skip to main content
Erschienen in: Journal of Cancer Survivorship 4/2011

01.12.2011

Cost-related medication nonadherence and cost-saving strategies used by elderly Medicare cancer survivors

verfasst von: Larissa Nekhlyudov, Jeanne Madden, Amy Johnson Graves, Fang Zhang, Stephen B. Soumerai, Dennis Ross-Degnan

Erschienen in: Journal of Cancer Survivorship | Ausgabe 4/2011

Einloggen, um Zugang zu erhalten

Abstract

Objectives

This study was conducted to compare cost-related medication nonadherence among elderly Medicare enrollees with and without cancer and to describe the strategies cancer survivors used to offset the costs of medications.

Methods

Using the 2005 Medicare Current Beneficiary Survey and Medicare claims, we compared self-reported cost-related medication nonadherence (CRN), spending less on basic needs to afford medicines, and cost reduction strategies among elderly beneficiaries with and without cancer. Descriptive statistics and logistic regression models were used to characterize and compare these populations.

Results

In a nationally representative sample of 9,818 non-institutionalized elderly Medicare enrollees, 1,392 (14%) were classified as cancer survivors based on Medicare claims. Cancer survivors were older, more highly educated, more likely to be male and non-Hispanic, and more likely to have multiple comorbidities, poorer health status, and employer-paid medication coverage. While 10% of cancer survivors and 11% without cancer reported CRN, about 6% and 9% (p = 0.004) of those with and without cancer, respectively, reported spending less on basic needs to offset the costs of medications. Cancer survivors who reported CRN (n = 143) had lower income (62.2% versus 48.6%, p = 0.11) and were more likely to be African-American (13.0% versus 6.4%, p = 0.033) and have non-employer-based medication insurance (p = 0.002) compared to those who did not report CRN. In adjusted analyses, CRN among the two groups was similar, but with some subgroup differences noted by gender and cancer type. Use of cost reduction strategies was mostly similar among cancer survivors and those without cancer.

Conclusion

Cost-related medication nonadherence medication is common among elderly Medicare beneficiaries, but appears to be similar among those with and without cancer.
Literatur
1.
Zurück zum Zitat Madden JM, Graves AJ, Zhang F, Adams AS, Briesacher BA, Ross-Degnan D, et al. Cost-related medication nonadherence and spending on basic needs following implementation of Medicare Part D. JAMA. 2008;299:1922–8.PubMedCrossRef Madden JM, Graves AJ, Zhang F, Adams AS, Briesacher BA, Ross-Degnan D, et al. Cost-related medication nonadherence and spending on basic needs following implementation of Medicare Part D. JAMA. 2008;299:1922–8.PubMedCrossRef
2.
Zurück zum Zitat Piette JD, Heisler M, Wagner TH. Problems paying out-of-pocket medication costs among older adults with diabetes. Diabetes Care. 2004;27:384–91.PubMedCrossRef Piette JD, Heisler M, Wagner TH. Problems paying out-of-pocket medication costs among older adults with diabetes. Diabetes Care. 2004;27:384–91.PubMedCrossRef
3.
Zurück zum Zitat Piette JD, Wagner TH, Potter MB, Schillinger D. Health insurance status, cost-related medication underuse, and outcomes among diabetes patients in three systems of care. Med Care. 2004;42:102–9.PubMedCrossRef Piette JD, Wagner TH, Potter MB, Schillinger D. Health insurance status, cost-related medication underuse, and outcomes among diabetes patients in three systems of care. Med Care. 2004;42:102–9.PubMedCrossRef
4.
Zurück zum Zitat Tamblyn R, Laprise R, Hanley JA, Abrahamowicz M, Scott S, Mayo N, et al. Adverse events associated with prescription drug cost-sharing among poor and elderly persons. JAMA. 2001;285:421–9.PubMedCrossRef Tamblyn R, Laprise R, Hanley JA, Abrahamowicz M, Scott S, Mayo N, et al. Adverse events associated with prescription drug cost-sharing among poor and elderly persons. JAMA. 2001;285:421–9.PubMedCrossRef
5.
Zurück zum Zitat Brown ML, Riley GF, Schussler N, Elzioni R. Estimating health care costs related to cancer treatment from SEER-Medicare data. Med Care. 2002;40(Supplemental IV):104–17. Brown ML, Riley GF, Schussler N, Elzioni R. Estimating health care costs related to cancer treatment from SEER-Medicare data. Med Care. 2002;40(Supplemental IV):104–17.
6.
Zurück zum Zitat Chang S, Long SR, Kutikova L, Bowman L, Finley D, Crown WH, et al. Estimating the cost of cancer: results on the basis of claims data analyses for cancer patients diagnosed with seven types of cancer during 1999 to 2000. J Clin Oncol. 2004;22:3524–30.PubMedCrossRef Chang S, Long SR, Kutikova L, Bowman L, Finley D, Crown WH, et al. Estimating the cost of cancer: results on the basis of claims data analyses for cancer patients diagnosed with seven types of cancer during 1999 to 2000. J Clin Oncol. 2004;22:3524–30.PubMedCrossRef
7.
Zurück zum Zitat Meropol NJ, Schulman KA. Cost of cancer care: issues and implications. J Clin Oncol. 2007;25:180–6.PubMedCrossRef Meropol NJ, Schulman KA. Cost of cancer care: issues and implications. J Clin Oncol. 2007;25:180–6.PubMedCrossRef
8.
Zurück zum Zitat Langa KM, Fendrick AM, Chernew ME, Kabeto M, Paisley KL, Hayman JA. Out-of-pocket health-care expenditures among older Americans with cancer. Value Health. 2004;7:186–94.PubMedCrossRef Langa KM, Fendrick AM, Chernew ME, Kabeto M, Paisley KL, Hayman JA. Out-of-pocket health-care expenditures among older Americans with cancer. Value Health. 2004;7:186–94.PubMedCrossRef
9.
Zurück zum Zitat The USA Today/Kaiser Family Foundation/Harvard School of Public Health. National survey of households affected by cancer. Menlo Park: The Henry J. Kaiser Family Foundation; 2006. The USA Today/Kaiser Family Foundation/Harvard School of Public Health. National survey of households affected by cancer. Menlo Park: The Henry J. Kaiser Family Foundation; 2006.
10.
Zurück zum Zitat Himmelstein DU, Warren E, Thorne D, Woolhandler S. Illness and injury as contributors to bankruptcy. Health Affairs 2005;Suppl W5:63–73. Himmelstein DU, Warren E, Thorne D, Woolhandler S. Illness and injury as contributors to bankruptcy. Health Affairs 2005;Suppl W5:63–73.
11.
Zurück zum Zitat Institute of Medicine and National Research Council of the National Academies. From cancer patient to cancer survivor: lost in transition. Washington: The National Academies; 2006. Institute of Medicine and National Research Council of the National Academies. From cancer patient to cancer survivor: lost in transition. Washington: The National Academies; 2006.
12.
Zurück zum Zitat Weaver KE, Rowland JH, Bellizzi KM, Aziz NM. Forgoing medical care because of cost. Assessing disparities in healthcare access among cancer survivors living in the United States. Cancer. 2010;116:3493–504.PubMedCrossRef Weaver KE, Rowland JH, Bellizzi KM, Aziz NM. Forgoing medical care because of cost. Assessing disparities in healthcare access among cancer survivors living in the United States. Cancer. 2010;116:3493–504.PubMedCrossRef
13.
Zurück zum Zitat Pierre-Jacques M, Safran DG, Zhang F, Ross-Degnan D, Adams AS, Gurwitz J, et al. Reliability of new measures of cost related medication nonadherence. Med Care. 2008;46:444–8.PubMedCrossRef Pierre-Jacques M, Safran DG, Zhang F, Ross-Degnan D, Adams AS, Gurwitz J, et al. Reliability of new measures of cost related medication nonadherence. Med Care. 2008;46:444–8.PubMedCrossRef
14.
Zurück zum Zitat Bambauer KZ, Safran DG, Ross-Degnan D, Zhang F, Adams AS, Gurwitz J, et al. Depression and cost-related medication nonadherence in Medicare beneficiaries. Arch Gen Psych. 2007;64:602–8.CrossRef Bambauer KZ, Safran DG, Ross-Degnan D, Zhang F, Adams AS, Gurwitz J, et al. Depression and cost-related medication nonadherence in Medicare beneficiaries. Arch Gen Psych. 2007;64:602–8.CrossRef
15.
Zurück zum Zitat Soumerai SB, Pierre-Jacques M, Ross-Degnan D, Adams AS, Gurwitz JH. Cost-related medication non-adherence among the elderly and the disabled: a national survey one year before the Medicare drug benefit. Arch Intern Med. 2006;166:1829–35.PubMedCrossRef Soumerai SB, Pierre-Jacques M, Ross-Degnan D, Adams AS, Gurwitz JH. Cost-related medication non-adherence among the elderly and the disabled: a national survey one year before the Medicare drug benefit. Arch Intern Med. 2006;166:1829–35.PubMedCrossRef
16.
Zurück zum Zitat Tjia J, Briesacher BA, Soumerai SB, Pierre-Jacques M, Zhang F, Ross-Degnan D, et al. Medicare beneficiaries and free prescription drug samples: a national survey. J Gen Intern Med. 2008;23:709–14.PubMedCrossRef Tjia J, Briesacher BA, Soumerai SB, Pierre-Jacques M, Zhang F, Ross-Degnan D, et al. Medicare beneficiaries and free prescription drug samples: a national survey. J Gen Intern Med. 2008;23:709–14.PubMedCrossRef
17.
Zurück zum Zitat Yabroff KR, Warren JL, Banthin J, Schrag D, Mariotto A, Lawrence W, et al. Comparison of approaches for estimating prevalence costs of care for cancer patients: what is the impact of data source? Med Care. 2009;47(Suppl):S64–9.PubMedCrossRef Yabroff KR, Warren JL, Banthin J, Schrag D, Mariotto A, Lawrence W, et al. Comparison of approaches for estimating prevalence costs of care for cancer patients: what is the impact of data source? Med Care. 2009;47(Suppl):S64–9.PubMedCrossRef
18.
Zurück zum Zitat Mohile SG, Xian Y, Dale W, Fisher SG, Rodin M, Morrow GR, et al. Association of a cancer diagnosis with vulnerability and frailty in older Medicare beneficiaries. J Natl Cancer Inst. 2009;101:1206–15.PubMedCrossRef Mohile SG, Xian Y, Dale W, Fisher SG, Rodin M, Morrow GR, et al. Association of a cancer diagnosis with vulnerability and frailty in older Medicare beneficiaries. J Natl Cancer Inst. 2009;101:1206–15.PubMedCrossRef
19.
Zurück zum Zitat Lash TL, Fox MP, Westrup JL, Fink AK, Silliman RA. Adherence to tamoxifen over the five-year course. Breast Cancer Res Treat. 2006;99:215–20.PubMedCrossRef Lash TL, Fox MP, Westrup JL, Fink AK, Silliman RA. Adherence to tamoxifen over the five-year course. Breast Cancer Res Treat. 2006;99:215–20.PubMedCrossRef
20.
Zurück zum Zitat Owusu C, Buist DSM, Field TS, Lash TL, Thwin SS, Geiger AM, et al. Predictors of tamoxifen discontinuation among older women with estrogen receptor-breast cancer. J Clin Oncol. 2008;26:549–55.PubMedCrossRef Owusu C, Buist DSM, Field TS, Lash TL, Thwin SS, Geiger AM, et al. Predictors of tamoxifen discontinuation among older women with estrogen receptor-breast cancer. J Clin Oncol. 2008;26:549–55.PubMedCrossRef
21.
Zurück zum Zitat Partridge AH, Wang PS, Winer EP, Avorn J. Nonadherence to adjuvant tamoxifen therapy in women with primary breast cancer. J Clin Oncol. 2003;21:602–6.PubMedCrossRef Partridge AH, Wang PS, Winer EP, Avorn J. Nonadherence to adjuvant tamoxifen therapy in women with primary breast cancer. J Clin Oncol. 2003;21:602–6.PubMedCrossRef
22.
Zurück zum Zitat Ruddy K, Mayer E, Partridge A. Patient adherence and persistence with oral anticancer treatment. CA Cancer J Clin. 2009;59:56–66.PubMedCrossRef Ruddy K, Mayer E, Partridge A. Patient adherence and persistence with oral anticancer treatment. CA Cancer J Clin. 2009;59:56–66.PubMedCrossRef
23.
Zurück zum Zitat Chlebowski RT, Geller ML. Adherence to endocrine therapy for breast cancer. Oncology. 2006;71:1–9.PubMed Chlebowski RT, Geller ML. Adherence to endocrine therapy for breast cancer. Oncology. 2006;71:1–9.PubMed
24.
Zurück zum Zitat Pezzin LE, O’Niel MB, Nattinger AB. The economic consequences of breast cancer adjuvant hormonal treatments. J Gen Intern Med. 2009;24 Suppl 2:S446–50.PubMedCrossRef Pezzin LE, O’Niel MB, Nattinger AB. The economic consequences of breast cancer adjuvant hormonal treatments. J Gen Intern Med. 2009;24 Suppl 2:S446–50.PubMedCrossRef
25.
26.
Zurück zum Zitat Krouse RS, Herrinton LJ, Grant M, Wendel CS, Green SB, Mohler MJ, et al. Health-related quality of life among long-term rectal cancer survivors with an ostomy: manifestations by sex. J Clin Oncol. 2009;27:4664–70.PubMedCrossRef Krouse RS, Herrinton LJ, Grant M, Wendel CS, Green SB, Mohler MJ, et al. Health-related quality of life among long-term rectal cancer survivors with an ostomy: manifestations by sex. J Clin Oncol. 2009;27:4664–70.PubMedCrossRef
Metadaten
Titel
Cost-related medication nonadherence and cost-saving strategies used by elderly Medicare cancer survivors
verfasst von
Larissa Nekhlyudov
Jeanne Madden
Amy Johnson Graves
Fang Zhang
Stephen B. Soumerai
Dennis Ross-Degnan
Publikationsdatum
01.12.2011
Verlag
Springer US
Erschienen in
Journal of Cancer Survivorship / Ausgabe 4/2011
Print ISSN: 1932-2259
Elektronische ISSN: 1932-2267
DOI
https://doi.org/10.1007/s11764-011-0188-4

Weitere Artikel der Ausgabe 4/2011

Journal of Cancer Survivorship 4/2011 Zur Ausgabe

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.