Costs of patient management over 18 months following a hip, clinical vertebral, distal forearm, or proximal humerus fragility fracture in France—results from the ICUROS study
- 12.10.2021
- Original Article
- Verfasst von
- Astrid Coassy
- Axel Svedbom
- Hervé Locrelle
- Roland Chapurlat
- Bernard Cortet
- Patrice Fardellone
- Philippe Orcel
- Christian Roux
- Fredrik Borgström
- John A. Kanis
- Thierry Thomas
- Erschienen in
- Osteoporosis International | Ausgabe 3/2022
Abstract
Summary
This observational study prospectively assessed direct and indirect costs related to patient management over 18 months following hip, clinical vertebral, humeral, or distal forearm fracture events in France. It appears that their levels were much higher than the previous estimates, raising the burden of osteoporosis-related fractures on public health expenditures.
Introduction
This prospective observational study assessed the costs related to patient management over the 18-month period following the event of a hip, clinical vertebral, humeral, or distal forearm fracture in France.
Methods
Individuals aged ≥ 50 years old with the diagnosis of a fragility fracture in six French University Hospitals were enrolled in the International Costs and Utilities Related to Osteoporotic Fractures Study (ICUROS). All resources used over the defined period and related to fracture and the underlying osteoporosis management were collected by questionnaires at baseline, 4 months, 12 months, and 18 months. Information was collected by direct or phone contact completed by patients’ records and interviews of partner, family, and general practitioners. Costs were estimated from a societal perspective, including direct and indirect costs. We implemented recursive partitioning analysis (RPA), a statistical learning algorithm to identify predictors of costs.
Results
Four hundred thirty-one patients (mean age 72.5 years; 84.6% women) were evaluated. Among them, 17.6% had a prior fracture in the last 5 years. Approximately half of the whole group lived alone in the community, and 56.8% were from a low- or middle-income category. Over the 18-month period of evaluation, total costs (including initial fracture-related and follow-up ones) were 23 926 €, 14 561 €, and 6 905 € for the hip, clinical vertebral, and distal forearm fracture, respectively. Over a year, costs related to a humeral fracture were 10 319 €. The RPA identified mobility impairment prior to fracture as a predictor of increase in costs related to fracture.
Conclusions
Our study for the first time prospectively assessed total costs related to the four main osteoporotic fractures in France. It appears that their levels were much higher than previous estimates, raising the burden of osteoporosis-related fractures on public health expenditures.
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- Titel
- Costs of patient management over 18 months following a hip, clinical vertebral, distal forearm, or proximal humerus fragility fracture in France—results from the ICUROS study
- Verfasst von
-
Astrid Coassy
Axel Svedbom
Hervé Locrelle
Roland Chapurlat
Bernard Cortet
Patrice Fardellone
Philippe Orcel
Christian Roux
Fredrik Borgström
John A. Kanis
Thierry Thomas
- Publikationsdatum
- 12.10.2021
- Verlag
- Springer London
- Erschienen in
-
Osteoporosis International / Ausgabe 3/2022
Print ISSN: 0937-941X
Elektronische ISSN: 1433-2965 - DOI
- https://doi.org/10.1007/s00198-021-06189-7
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