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Erschienen in: Internal and Emergency Medicine 3/2022

28.07.2021 | COVID-19 | EM - ORIGINAL Zur Zeit gratis

A rapid and feasible tool for clinical decision making in community-dwelling patients with COVID-19 and those admitted to emergency departments: the Braden-LDH-HorowITZ Assessment—BLITZ

verfasst von: Erik Lagolio, Jacopo Demurtas, Roberto Buzzetti, Giorgio Cortassa, Stefania Bottone, Laura Spadafora, Cristina Cocino, Lee Smith, Thomas Benzing, Maria Cristina Polidori

Erschienen in: Internal and Emergency Medicine | Ausgabe 3/2022

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Abstract

There is no univocal standardized strategy to predict outcomes and stratify risk of SARS-CoV-2 infected patients, notably in emergency departments. Our aim is to develop an accurate indicator of adverse outcomes based on a retrospective analysis of a COVID-19 database established at the Emergency Department (ED) of a North-Italian hospital during the first wave of SARS-CoV-2 infection. Laboratory, clinical, psychosocial and functional characteristics including those obtained from the Braden Scale—a standardized scale to quantify the risk of pressure sores which takes into account aspects of sensory perception, activity, mobility and nutrition—from the records of 117 consecutive patients with swab-positive COVID-19 disease admitted to the Emergency Medicine ward between March 1, 2020 and April 15, 2020 were included in the analysis. Adverse outcomes included admission to the Intensive Care Unit (ICU) and in-hospital death. Among the parameters collected, the highest cutoff sensitivity and specificity scores to best predict adverse outcomes were displayed by lactate dehydrogenase (LDH) blood value at admission > 439 U/L, Horowitz Index (P/F Ratio) < 257 and Braden score < 18. The estimation power reached 93.6%. We named the assessment BLITZ (Braden-LDH-HorowITZ). Despite the retrospective and preliminary nature of the data, a multidimensional tool to assess overall functions, not chronological age, produced the highest prediction power for poor outcomes in relation to SARS-CoV-2 infection. Further analyses are now needed to establish meaningful correlations between ventilation therapies and multidimensional frailty as assessed by ad-hoc validated and standardized tools.
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Metadaten
Titel
A rapid and feasible tool for clinical decision making in community-dwelling patients with COVID-19 and those admitted to emergency departments: the Braden-LDH-HorowITZ Assessment—BLITZ
verfasst von
Erik Lagolio
Jacopo Demurtas
Roberto Buzzetti
Giorgio Cortassa
Stefania Bottone
Laura Spadafora
Cristina Cocino
Lee Smith
Thomas Benzing
Maria Cristina Polidori
Publikationsdatum
28.07.2021
Verlag
Springer International Publishing
Schlagwort
COVID-19
Erschienen in
Internal and Emergency Medicine / Ausgabe 3/2022
Print ISSN: 1828-0447
Elektronische ISSN: 1970-9366
DOI
https://doi.org/10.1007/s11739-021-02805-w

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