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21.01.2022 | COVID-19 | COVID-19 Zur Zeit gratis

Chronic fatigue syndrome and cognitive deficit are associated with acute-phase neuropsychiatric manifestations of COVID-19: A 9-month follow-up study

verfasst von: Fatemeh Sadat Mirfazeli, Atiye Sarabi-Jamab, Victor Pereira-Sanchez, Alireza Kordi, Behnam Shariati, Seyed Vahid Shariat, Salar Bahrami, Shabnam Nohesara, Mostafa Almasi-Dooghaee, Seyed Hamid Reza Faiz

Erschienen in: Neurological Sciences | Ausgabe 4/2022

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Abstract

The preva lence of long-COVID symptoms is rising but it is not still possible to predict which patients will present them, and which types of symptoms they will present. We followed up 95 patients with confirmed COVID-19 for 9 months to identify and characterize long-COVID symptoms. Easy fatigability was the most common symptom (51.04%), followed by anxiety (38.54%), dyspnea (38.54%), and new-onset headache (38.54%). There was no association between COVID-19 severity in the acute phase and the number of long-COVID symptoms (F(1,93) = 0.75, p = 0.45), and cognitive function (MoCA) scores (F(1,90) = 0.073, p = 0.787) at follow-up. Being female (F(1,92) =  − 2.27, p = 0.02), having a higher number of symptoms (F(1,93) = 2.76, p = 0.0068), and experiencing constitutional neuropsychiatric symptoms (F(1,93) = 2.529, p = 0.01) in the acute phase were associated with having chronic fatigue syndrome at follow-up. Moreover, constitutional neuropsychiatric symptoms in the acute phase were associated with a lower MoCA score (F(1,93) = 10.84, p = 0.001) at follow-up. Specific clinical presentations such as constitutional neuropsychiatric symptoms in the acute phase might be predictors of debilitating long-COVID symptoms such as chronic fatigue syndrome and cognitive deficits.
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Metadaten
Titel
Chronic fatigue syndrome and cognitive deficit are associated with acute-phase neuropsychiatric manifestations of COVID-19: A 9-month follow-up study
verfasst von
Fatemeh Sadat Mirfazeli
Atiye Sarabi-Jamab
Victor Pereira-Sanchez
Alireza Kordi
Behnam Shariati
Seyed Vahid Shariat
Salar Bahrami
Shabnam Nohesara
Mostafa Almasi-Dooghaee
Seyed Hamid Reza Faiz
Publikationsdatum
21.01.2022
Verlag
Springer International Publishing
Schlagwort
COVID-19
Erschienen in
Neurological Sciences / Ausgabe 4/2022
Print ISSN: 1590-1874
Elektronische ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-021-05786-y

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