14.12.2021 | COVID-19 | Correction
Correction to: Role of total lung stress on the progression of early COVID‑19 pneumonia
Erschienen in: Intensive Care Medicine | Ausgabe 3/2022
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The original version of this article unfortunately contained mistakes in Table 2 (wrong confidence interval data of “PEEP” and groups' size). Please find the corrected table below.
Overall (n = 140)
|
No ARDS (n = 17)
|
Mild ARDS (n = 45)
|
Mild-moderate ARDS (n = 33)
|
Moderate-severe ARDS (n = 36)
|
Severe ARDS (n = 9)
|
p value
|
|
---|---|---|---|---|---|---|---|
Gas exchange
|
|||||||
PaO2 (mmHg)
|
104 [79–140]
|
226 [187–259]
|
143 [102–151]
|
112 [100–123]
|
83.2 [75.9–93.6]
|
65.1 [59.3–69]
|
< 0.001*
|
FiO2
|
0.6 [0.6–0.7]
|
0.6 [0.6–0.7]
|
0.6 [0.5–0.7]
|
0.7 [0.5–0.7]
|
0.7 [0.6–0.7]
|
0.8 [0.7–0.8]
|
< 0.001*
|
PaCO2 (mmHg)
|
37 [33.9–40.7]
|
38.3 [32.6–42.0]
|
35.9 [32.6–39]
|
38.8 [35–41]
|
36.5 [34.8–40.8]
|
39 [34.2–39.9]
|
0.37
|
pH
|
7.44 [7.42–7.47]
|
7.44 [7.42–7.46]
|
7.45 [7.43–7.48]
|
7.44 [7.43–7.47]
|
7.44 [7.42–7.46]
|
7.43 [7.42–7.45]
|
0.52
|
Respiratory rate (bpm)
|
20 [18–24]
|
16 [15–20]
|
21 [18–23]
|
21 [18–24]
|
21 [18–25]
|
20 [18–20]
|
0.039*
|
PEEP (cmH2O)
|
7.5 [7.5–10]
|
10 [7.5–10]
|
8 [7.5–10]
|
8 [7.5–10]
|
9 [7.5–10]
|
10 [10–10]
|
0.24
|
Esophageal pressure swing (cmH2O)
|
7 [5–10]
|
6 [5–7]
|
7 [5–9]
|
7 [4–9]
|
9 [7–12]
|
7 [5–7]
|
0.06
|
Total stress (cmH2O)
|
14 [11.5–16.3]
|
13 [11.8–15]
|
13.2 [11.3–16]
|
13.8 [11–16]
|
15.2 [12.9–18.6]
|
14 [13.3–16.8]
|
0.12
|
Borg dyspnea scale
|
0 [0–1]
|
0 [0–1]
|
0 [0–0]
|
0 [0–0]
|
0 [0–1]
|
0 [0–1]
|
0.34
|
PEEP-test
|
|||||||
SpO2 at 0 cmH2O (%)
|
97 [93–99]
|
98 [94–100]
|
98 [96–99]
|
98 [95–99]
|
95 [93–98]
|
91 [88–94]
|
0.003*
|
SpO2 at 10 cmH2O (%)
|
98 [96–99]
|
99 [98–100]
|
99 [97–100]
|
98 [97–99]
|
97 [96–98]
|
94 [94–98]
|
0.006*
|
Respiratory rate at 0 cmH2O (bpm)
|
22 [18–28]
|
18 [15–20]
|
22 [18–28]
|
23 [20–28]
|
22 [19–27]
|
24.5 [22–27]
|
0.010*
|
Respiratory rate at 10 cmH2O (bpm)
|
20 [16–24]
|
16 [15–18]
|
20 [17–22]
|
22 [18–25]
|
20 [17–28]
|
19.5 [18–21]
|
0.007*
|
Esophageal pressure swing at 0 cmH2O (cmH2O)
|
8 [6–12]
|
7 [5–7]
|
8 [5–10]
|
8 [5–12]
|
8 [7–15]
|
8.8 [6–11]
|
0.36
|
Esophageal pressure swing at 10 cmH2O (cmH2O)
|
7 [5–10]
|
7.5 [6–9]
|
7 [5–9]
|
7 [4–9]
|
9 [7–12]
|
7 [6–9]
|
0.07
|
Total stress at 0 cmH2O (cmH2O)
|
8 [6–12]
|
7 [5–10]
|
8 [5–10]
|
8 [5–12]
|
8 [7–15]
|
9 [6–11]
|
0.36
|
Total stress at 10 cmH2O (cmH2O)
|
14 [12–17]
|
14.5 [13–16.3]
|
14 [12–16]
|
14 [11.3–16.3]
|
16 [14–18.5]
|
14 [13.4–15.6]
|
0.07
|